Benzoxazines
TARGETMOL CHEMICALS INC FORETINIB 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Foretinib (GSK1363089) is a broad-spectrum tyrosine kinase inhibitor with IC50s of 0.4 nM and 0.9 nM for Met and KDR. purity: 99%
TARGETMOL CHEMICALS INC RSL3 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1000 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. RSL3 (RSL3 1S) is a VDAC-independent ferroptosis activator with selectivity for tumor cells bearing oncogenic RAS. RSL3 is the inhibitor of the glutathione peroxidase 4 which can inhibit the cysteine/glutamate amino acid transporter system xc- that blocks GSH synthesis (IC50 100 nM). purity: 99%
TARGETMOL CHEMICALS INC CZ415 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CZ415 is a potent and highly selective mTOR inhibitor. purity: 98%
TARGETMOL CHEMICALS INC PF-02413873 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. PF-02413873 is a competitive antagonist of nonsteroidal progesterone receptor with a Ki of 2.6 nM. PF-02413873 can be used in studies about the treatment of gynecological conditions such as endometriosis. purity: 99%
TARGETMOL CHEMICALS INC EF24 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. EF24 (35-Bis[(2-fluorophenyl)Methylene]-4-piperidinone) treatment increases the levels of activated caspase 3 and 9 and decreases the phosphorylated forms of MEK1 and ERK. EF24 shows potent anti-tumor activity in oral squamous cell carcinoma (OSCC) via deactivation of the MAPK/ERK signaling pathway. purity: 98%
TARGETMOL CHEMICALS INC CP 866087 5MG
Also available in 1mg 10mg 25mg 50mg and bulk. Please contact Fisher for quotes. CP 866087 is an opioid receptor antagonist for the study of female sexual dysfunction. purity: 99%
TARGETMOL CHEMICALS INC ASTAXANTHIN 50MG
Also available in 2 mg 5 mg 10 mg 25 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Astaxanthin (trans-Astaxanthin) is a keto-carotenoid in the terpenes class of chemical compounds. It is classified as a xanthophyll but it is a carotenoid with no vitamin A activity. It is present in most red-colored aquatic organisms. Astaxanthin has shown to mediate anti-oxidant and anti-inflammatory actions. It may be found in fish feed or some animal food as a color additive. purity: 99%
TARGETMOL CHEMICALS INC GERMACRONE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Germacrone a major active component found in Curcuma zedoaria oil product shows anti-inflammatory antiandrogenic and antivirus activities. It also inhibits the proliferation of glioma cells by promoting apoptosis. purity: 99%
TARGETMOL CHEMICALS INC DEHYDROANDROGRAPHOLIDE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Dehydroandrographolide is a natural compound extracted from herbal medicine Andrographis paniculata (Burm f) Nees. purity: 99%
TARGETMOL CHEMICALS INC HMN-214 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. HMN-214 (IVX-214) is a potent PLK1 inhibitor with an average IC50 of 0.12 uM. purity: 99%
TARGETMOL CHEMICALS INC ABEMACICLIB 100MG
Also available in 5 mg 25 mg 50 mg 200 mg 500 mg 1000 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Abemaciclib (CDK4/6 dual inhibitor) is an effective and specific CDK4/6 inhibitor (IC50 2/10 nM). purity: 99%
TARGETMOL CHEMICALS INC BLU9931 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. BLU9931 is the first selective small molecule inhibitor of FGFR4. purity: 99%
TARGETMOL CHEMICALS INC GANETESPIB 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Ganetespib (STA-9090) is a synthetic small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. purity: 99%
TARGETMOL CHEMICALS INC TRANILAST 100MG
Also available in 5 mg 10 mg 25 mg 50 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Tranilast (SB 252218) an antiallergic drug suppresses lipid mediator and cytokine release from inflammatory cells therefore utilized in the treatment of allergic disorders. purity: 99%
TARGETMOL CHEMICALS INC SANT-1 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SANT-1 directly binds to Smoothened (Smo) receptor (Kd 1.2 nM) and inhibits Smo agonist effects (IC50 20 nM). purity: 99%