Benzoxazines
AdipoGen BHHT
Chemical. CAS 200862-69-7. Formula C30H16F14O4. MW 706.42. Synthetic. Chelating label for europium Eu3. Builds luminescent complexes that can be directly bound to proteins and detected.
AdipoGen Bromomethyl-7-methoxycoumarin
Chemical. CAS 35231-44-8. Formula C11H9BrO3. MW 269.09. Synthetic. Blue fluorescent labeling reagent for fatty acids and carboxylates. Used for fluorometric analysis, derivatization, and TLC and HPLC separation of a range of naturally occurring acids. Used as a substrate for measuring histone acetyltransferase HATs, peptidases and sirtuin activity.
AdipoGen 6-Amino-D-luciferin
Chemical. CAS 161055-47-6. Formula C11H9N3O2S2. MW 279.34. Synthetic. Amino analog of the common D-luciferin substrate for use in measuring firefly luciferase activity. This cell permeable reagent can be used when considering design of proluminescent bioconjugates peptidase substrates of luciferin for ultrasensitive luminescent assays. In bioluminescent protease assays peptides or amino acids are conjugated to the luciferin analog 6-amino-D-luciferin. These substrates are useful for ultrasensitive analysis of a variety of protease enzymes including various caspases and cathepsins, chymotrypsin, trypsin, elastase, kallikrein, thrombin, ficin, bromoalain, plasmin, papain, ficin and many others or even for use in vivo tracing of luciferase transfected cells in living tissues. The resulting bioluminescence spectrum of reaction of 6-Amino-D-luciferin is very similar to that observed for the natural substrate D-luciferin.
AdipoGen 6-Aminoseleno-D-luciferin
Chemical. CAS 1375964-28-5. Formula C11H9N3O2SSe. MW 326.23. Synthetic. Firefly luciferase substrate. Selenium analog of firefly L-luciferin with red-shifted bioluminescence emission for use in in vivo bioluminescence imaging. Bioluminescence spectra max. 600nm. This selenium analog exhibits a similar substrate affinity to wild type D-luciferin, though with slightly lower quantum yield.
AdipoGen 4-Azido-7-nitrobenzofurazan
Chemical. CAS 10199-90-3. Formula C6H2N6O3. MW 206.12. Synthetic. Non-fluorescent azido fluorogen which can be photoactivated to the longer wavelength amino version that is fluorescent. Building block and reagent for synthesis of fluorescent probes. Used for the preparation of fluorogenic substrates, chemosensors and probes, which can be concerted to the high fluoresence NBD-amine after release. Fluorescent chemosensor for hydrogen sulfide. Spectral data Ex=384 454nm, Em=550nm.
AdipoGen Azo-Carob Galactomannan
Chemical. CAS n.a. Synthetic Remazol brilliant blue-dyed galactomannan polysaccharide. Soluble substrate for the specific measurement of endo-1,4-beta-D-mannanase/galactomannase. Used for the measurement of enzyme activity, for research, biochemical enzyme assays and in vitro diagnostic analysis.
AdipoGen Amplex Red
Chemical. CAS 119171-73-2. Formula C14H11NO4. MW 257.24. Synthetic. 10-acetyl-3,7-dihydroxyphenoxazin Amplex Red is a non-fluorescent, highly sensitive and stable probe for H2O2. Amplex Red is an applicable as a fluorogenic substrate for peroxidase. In the presence of horseradish peroxidase HRP, the Amplex Red reagent reacts in a 11 stechiometry with H2O2 to produce highly fluorescent resorufin. Because H2O2 is produced in many different enzymatic reactions, the Amplex Red reagent allows researchers to detect the activity of many different enzymes. 10-acetyl-3,7-dihydroxyphenoxazin has absorption and fluorescence emission maxima of approximately 563 nm and 587 nm, respectively, and because its extinction coefficient is high 54,000 cm-1M-1, the assay can be performed either fluorometrically or spectrophotometrically.
AdipoGen AMCA-H
Chemical. CAS 106562-32-7. Formula C12H11NO4. MW 233.22. Synthetic. AMCA is one of the brightest amine-reactive blue fluorescent dyes useful for immunofluorescence and fluorescent labeling Ex/Em 353/455nm. It is quite photostable, and its fluorescence is pH-independent from pH 4 to 10. The properties include a relatively large Stokes shift and resistance to photobleaching. Reactive AMCA derivatives are used as contrasting probes for double and triple labeling in immunofluorescence microscopy, arrays and in situ hybridization. NHS-AMCA and Sulfo-NHS-AMCA are reactive towards primary amine groups on antibodies, proteins, peptides and other biomolecules. AMCA-Hydrazide is used to label glycosylation sites or for conjugation to carboxyl groups using the crosslinker EDC.
AdipoGen Luteoreticulin
Chemical. CAS 22388-89-2. Formula C19H19NO5. MW 341.4. Isolated from Streptomyces thioluteus. Nitrophenyl pyranone derivative related to aureothin Prod. No. BVT-0303 http//www.adipogen.com/bvt-0303/aureothin.html . Insecticidal and nematocidal compound. Metabolites within this product class show pronounced antitumor and immunosuppressive activity.
AdipoGen Chaetoglobosin C
Chemical. CAS 50645-76-6. Formula C32H36N2O5. MW 528.7. Isolated from Chaetomium sp. Cytochalasan mycotoxin, derivative of chaetoglobosin A Prod. No. BVT-0092 http//www.adipogen.com/bvt-0092/chaetoglobosin-a.html . Phytotoxic and antifungal compound. Moderate cytotoxic compound.
AdipoGen Eremofortin B
Chemical. CAS 60048-73-9. Formula C15H20O3. MW 248.3. Isolated from Penicillium roqueforti. Eremophilane sesquiterpene. Nontoxic secondary metabolite from Penicillium roqueforti.
AdipoGen Pikromycin
Chemical. CAS 19721-56-3. Formula C28H47NO8. MW 525.7. Isolated from Streptomyces sp. Antibiotic. 14-Membered macrolide. Active against Gram-positive bacteria including mycobacteria. Prolyl endopeptidase PREP inhibitor.
AdipoGen Aurofusarin
Chemical. CAS 13191-64-5. Formula C30H18O12. MW 570.5. Isolated from Fusarium graminearum. Dimeric naphthoquinone. Antibiotic activity. Mycotoxin. Toxic against mammalians and avian species. Analytical standard in food industry.
AdipoGen Antibiotic PF 1052
Chemical. CAS 147317-15-5. Formula C26H39NO4. MW 429.6. Isolated from Phoma sp. Antibiotic. Antibacterial, antifungal and phytotoxic.
AdipoGen 5-Aminoeosin
Chemical. CAS 75900-75-3. Formula C20H9Br4NO5. MW 662.9. Synthetic. Fluorescent marker used extensively in microscopy studies. Can be used in photoluminometric immunoassays for the formation of conjugates with immunoreactants by fluorescent energy transfer.