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Benzoxazolines

Organic heterocyclic compounds that consist of benzene fused with an oxazolines; oxazolines are a five-membered ring with three carbon atoms, one oxygen atom, and one nitrogen atom.

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1

Medchemexpress LLC Iny-03-041 | 2503017-97-6 | 99.7% | C44H56ClN7O5 | 10MG
SDP

INY-03-041 is a PROTAC pan-AKT degrader that links an ATP-competitive AKT inhibitor to a cereblon ligand to induce targeted degradation of AKT isoforms in biochemical and cellular studies. The compound is supplied as a high-purity solid for research use.

  • Potent degradation of AKT1, AKT2, and AKT3 with low-nanomolar activity.
  • Enables investigation of AKT signaling through targeted protein degradation.
  • High purity solid suitable for biochemical and cellular assays.
  • Recommended sealed storage at -20°C; in solvent, store at -80°C for extended stability.
  • Available in small research pack sizes for screening and mechanistic experiments.

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2

Medchemexpress LLC Protac pan-AKT degrader (ipatasertib-lenalidomide conjugate) | 2503017-97-6 | 99.7% | 798.41 g·mol⁻¹ | C44H56ClN7O5 | 5 MG
SDP

A potent, selective PROTAC-based pan-AKT degrader that links an ATP-competitive AKT inhibitor to a cereblon ligand to induce degradation of AKT1, AKT2, and AKT3. It is supplied as a white to off-white solid for research use in biochemical and cellular studies of AKT signaling and degradation mechanisms.

  • Potent degradation of AKT isoforms with low-nanomolar activity.
  • High chemical purity (≈99.7%).
  • Molecular weight 798.41 g·mol⁻¹ and formula C44H56ClN7O5.
  • White to off-white solid form.
  • Storage: sealed, away from moisture; in solvent -80°C up to 6 months, -20°C up to 1 month.
  • Suitable for biochemical and cellular AKT pathway studies.

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3

Medchemexpress LLC 2-(4-oxo-1,2,3-benzotriazin-3-yl)-N-[(1S)-1-[4-(trifluoromethoxy)phenyl]ethyl]acetamide | 1929519-13-0 | MFCD32858822 | 99.9% | 392.33 g·mol^-1 | C18H15F3N4O3 | 5 MG
SDP

Zelatriazin is a selective GPR139 agonist provided for research use to study GPR139-mediated signaling and potential treatments for negative symptoms of schizophrenia. Supplied as a high-purity solid, it includes validated activity and stability information suitable for in vitro and in vivo laboratory workflows.

  • Selective GPR139 agonist with EC50 ≈ 22 nM.
  • High purity (≈99.9%) suitable for research assays.
  • Molecular formula C18H15F3N4O3; molecular weight 392.33 g·mol^-1.
  • Available in small research sizes (for example, 5 mg).
  • Powder stability: -20°C up to 3 years; 4°C up to 2 years.
  • Solvent solution stability: -80°C up to 6 months; -20°C up to 1 month.
  • For research use only; not for human or clinical use.

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