Biotin and derivatives
Medchemexpress LLC DBCO-biotin | 1418217-95-4 | MFCD22380751 | 98.5% | 502.63 | C28H30N4O3S | 50MG
DBCO-Biotin is an alkyl chain-based PROTAC linker and click-chemistry reagent that contains a dibenzocyclooctyne (DBCO) moiety conjugated to biotin, enabling copper-free strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. Supplied as a white to off-white solid, it is used for biotinylation, conjugation, and PROTAC synthesis in chemical biology applications.
- High purity of 98.5%.
- Molecular weight 502.63 g/mol.
- Molecular formula C28H30N4O3S.
- Soluble in DMSO at 31.25 mg/mL (62.17 mM).
- Store protected from light under inert gas; solid recommended at -20°C.
- Packaged as 50 mg vial.
- Enables copper-free click conjugation via SPAAC.
Medchemexpress LLC Recombinant human IGF2R protein, biotinylated | 50UG
Biotinylated recombinant human IGF2R protein (E47-M1508) is supplied as a lyophilized HEK293-expressed construct with C-terminal His and Avi tags for affinity purification and site-specific biotinylation. The product is intended for research on receptor-ligand interactions, intracellular trafficking, and related biochemical assays.
- Biotinylated recombinant protein suitable for ligand binding and trafficking studies.
- C-terminal His and Avi tags enable affinity purification and site-specific biotinylation.
- Expressed in mammalian HEK293 cells to preserve native glycosylation.
- Construct spans E47-M1508, covering relevant extracellular domains.
- Glycosylated protein with an apparent molecular weight of approximately 165-200 kDa.
- Lyophilized formulation with protectant; endotoxin level <1 EU/μg and recommended storage at -20°C.
![eMolecules 58-85-5 | Biotin | Ambeed | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 10g | 518521733](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000169626.jpg-250.jpg)
eMolecules 58-85-5 | Biotin | Ambeed | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 10g | 518521733
Biotin | Ambeed | 58-85-5 | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 10g | 518521733
Medchemexpress LLC Biotin-PEG5-NHS ester | 98.0% | 632.72 | 250 MG
Biotin-PEG5-NHS ester is a heterobifunctional crosslinker and a polyethylene glycol-containing bioconjugation reagent. It is utilized in scientific research for developing highly sensitive biosensors, targeted drug delivery systems, immunofluorescence imaging, and protein affinity purification, serving as a tool for precise biomolecule labeling and functionalization.
- Efficiently introduces biotin tags onto primary amine groups.
- Forms stable amide bonds under mild conditions.
- Incorporates a flexible spacer arm for increased molecular freedom.
- Enhances water solubility.
- Reduces non-specific adsorption.
Medchemexpress LLC Dbco-biotin | 1418217-95-4 | MFCD22380751 | 98.5% | 502.63 g/mol | C28H30N4O3S | 25MG
DBCO-Biotin is a copper-free click chemistry reagent that installs a biotin tag on azide-functionalized biomolecules via strain-promoted alkyne-azide cycloaddition (SPAAC). Supplied as a white powder, it is used for bioconjugation, affinity purification and detection, and as a linker component in targeted degrader synthesis. Store at -20 °C, protect from light, and maintain under inert atmosphere when possible.
- Enables copper-free SPAAC bioconjugation to azide-labeled targets.
- Introduces a biotin affinity handle for pull-down and detection assays.
- High purity suitable for analytical and preparative applications.
- Stable solid form when stored at -20 °C and protected from light.
- Compatible with proteins, peptides, and other biomolecules.
Medchemexpress LLC B7-H4 Human Biotin 100ug | 100ug
The B7-H4 protein acts as a negative regulator inhibiting T cell-mediated immune responses including activation proliferation cytokine production and cytotoxicity When expressed on tumor macrophages it cooperates with regulatory T cells to suppress tumor-associated antigen-specific T cell immunity B7-H4 Protein Human (Biotinylated HEK293 His-Avi) is the recombinant human-derived B7-H4 protein expressed by HEK293 with C-Avi C-His labeled tag
Medchemexpress LLC PD-L1 Mouse Biotin 100ug | 100ug
PD-L1 protein serves as a ligand for the inhibitory receptor PDCD1/PD-1 and is critical for maintaining immune tolerance This interaction modulates T cell activation limits effector responses and may stimulate IL10-producing T cell subsets PD-L1 Protein Mouse (Biotinylated HEK293 His) is the recombinant mouse-derived PD-L1 protein expressed by HEK293 with C-His labeled tag