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Biotin and derivatives

Organic heterocyclic compounds and derivatives that consist of a ureido ring and a tetrahydrothiophene ring; ureido contains the radical: NH2CONH−, and tetrahydrothiophene is a five-membered ring consisting of four carbon atoms and a sulfur atom.

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Medchemexpress LLC Acetic acid, 2-(2-cyclooctyn-1-yloxy)-, 2,5-dioxo-1-pyrrolidinyl ester | 1425803-45-7 | MFCD28898688 | >95.0% | 279.29 | C14H17NO5 | 5 MG
SDP

Cyclooctyne-O-NHS ester is an NHS-activated cyclooctyne reagent used as a cleavable linker and click-chemistry reagent for in vitro bioconjugation and antibody-drug conjugate synthesis. The molecule combines a strained alkyne for azide-alkyne cycloaddition with an activated ester to enable efficient amine coupling.

  • Enables azide-alkyne cycloaddition reactions for bioorthogonal conjugation.
  • Activated NHS ester facilitates rapid coupling to primary amines.
  • Designed for use as a cleavable linker in ADC synthesis and related conjugation workflows.
  • Provided in small, laboratory-scale quantities suitable for research use.
  • Accompanied by datasheet, certificate of analysis, and safety data sheet for traceability and safety.

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