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Vonoprazan Fumarate (TAK-438) is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H /K ATPase with IC50 of 19 nM (pH 6 5) controls gastric acid secretion Phase 3
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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. KT-362 fumarate is a novel compound that acts as an antagonist of calcium channels potassium channels and sodium channels.KT-362 fumarate causes vasodilation by affecting intracellular calcium mobilization in atrial muscle cells.KT-362 fumarate has a relaxing effect on femoral and basilar artery strips in rabbits. purity: 99%
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Ibutilide Fumarate (CAS 122647-32-9) is a small molecule classified as a Class III antiarrhythmic agent It acts primarily by enhancing slow inward sodium currents and delaying repolarization through inhibition of the rapid component of the cardiac delayed rectifier potassium current (IKr) resulting in prolongation of the cardiac action potential Ibutilide is utilized in research to investigate pharmacological cardioversion of atrial arrhythmias specifically studying the acute conversion of atrial fibrillation and atrial flutter to normal sinus rhythm Its properties make it valuable for exploring the mechanisms of antiarrhythmic therapy and cardiac electrophysiology
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Ibutilide Fumarate (CAS 122647-32-9) is a small molecule classified as a Class III antiarrhythmic agent It acts primarily by enhancing slow inward sodium currents and delaying repolarization through inhibition of the rapid component of the cardiac delayed rectifier potassium current (IKr) resulting in prolongation of the cardiac action potential Ibutilide is utilized in research to investigate pharmacological cardioversion of atrial arrhythmias specifically studying the acute conversion of atrial fibrillation and atrial flutter to normal sinus rhythm Its properties make it valuable for exploring the mechanisms of antiarrhythmic therapy and cardiac electrophysiology
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Also available in 10 mg 25 mg 50 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Ibutilide Fumarate (U70226E) is the fumarate salt form of ibutilide a class III antiarrhythmic agent. Ibutilide exerts its effect by activating a slow inward predominately sodium current rather than by blocking outward potassium currents. This results in prolongation of atrial and ventricular action potential duration and refractory periods. Ibutilide slightly decreases the sinus rate and atrioventricular (AV) conduction and produces a dose-related prolongation of the QT interval. purity: 99%
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More