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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Lecozotan HCl (SRA-333) is a potent and selective 5-HT antagonist that significantly enhances KCl-stimulated glutamate and acetylcholine release from the hippocampal dentate gyrus and has cognitive enhancing properties. Chronic administration of Lecozotan HCl did not induce 5-HT(1A) receptor tolerance or desensitization in a behavioral model demonstrating 5-HT(1A) receptor function. purity: 99%
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Trontinemab (RG6102) is a brain-penetrant anti-amyloid bispecific and humanizedized IgG1- antibody targeting to A plaques and transferrin receptor 1 (TFR1) Trontinemab binds to fibrillar A as well as A plaques triggering plaque clearance by engaging immune cells on Alzheimer disease (AD) brain sections Trontinemab also shows specific affinity to cynomolgus and human TFR1[1][2][3][4]
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