Dioxolanes
Medchemexpress LLC LAH5, 10 mg, CAS No. : 476169-12-7
LAH5 is an amphipathic cell-penetrating peptide. LAH5 effectively delivers CRISPR-Cas9 components into the nuclei of target cells by forming nanocomplexes with both RNP and RNP/HDR cargo.
Medchemexpress LLC sparstolonin B | 1259330-61-4 | 268.22 g/mol | 10MG
sparstolonin B | 1259330-61-4 | 268.22 g/mol | 10MG
Medchemexpress LLC EAI001 10mg | CAS No. : 892772-75-7
EAI001 is a potent, selective mutant epidermal growth factor receptor (EGFR) allosteric inhibitor with an IC50 value of 24 nM for EGFRL858R/T790M. EAI001 can be used for research of cancer.
Selleck Chemical LLC SRI-37330 HCl-E1272-5MG
SRI-37330 HCl(EX-A5854) an anti-diabetic drug is an orally bioavailable inhibitor of thioredoxin-interacting protein (TXNIP) with an IC50 of 0 64 M for TXNIP expression in INS-1 cells Its treatment inhibits glucagon secretion and function decreases hepatic glucose production and reverses hepatic steatosis
Cayman Chemical ANTIBODY RotlerIn 10mg
A mixture of the potent and selective CB1 receptor antagonist SLV 319 (Ki 7 8 nM) and its distomer SLV 319 ( )-enantiomer
Cayman Chemical ErtuglIflozIn 10mg
A dual inhibitor of mTOR and DNA-PK (IC50s 0 021 and 0 013 UM respectively) selective for mTOR and DNA-PK over PI3Ka ATM and ATR (IC50s 0 85 30 and 30 UM respectively) inhibits growth in a panel of 123 cancer cell lines including breast head and neck and lung cancer cells (GI50s 0 015-1 77 UM) inhibits NHEJ in CAL-51 MDA-MB-231 PC3 and HCT116 cells (IC50s 3 15 2 16 2 72 and 6 35 UM respectively) reduces tumor growth in a PC3 prostate cancer mouse xenograft model at 0 25 0 5 and 1 mg/kg twice per day
Cayman Chemical ErtuglIflozIn 25mg
A dual inhibitor of mTOR and DNA-PK (IC50s 0 021 and 0 013 UM respectively) selective for mTOR and DNA-PK over PI3Ka ATM and ATR (IC50s 0 85 30 and 30 UM respectively) inhibits growth in a panel of 123 cancer cell lines including breast head and neck and lung cancer cells (GI50s 0 015-1 77 UM) inhibits NHEJ in CAL-51 MDA-MB-231 PC3 and HCT116 cells (IC50s 3 15 2 16 2 72 and 6 35 UM respectively) reduces tumor growth in a PC3 prostate cancer mouse xenograft model at 0 25 0 5 and 1 mg/kg twice per day
TARGETMOL CHEMICALS INC GKI-1 HCL 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. GKI-1 HCl is a Greatwall (GWL) kinase inhibitor that inhibits hGWLFL and hGWL-KinDom.The inhibitory effect of GKI-1 HCl on ROCK1 is more significant.
TARGETMOL CHEMICALS INC ND-322 HCL 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. ND-322 HCl (ND 322 Hydrochloride) is a selective inhibitor of MT1-MMP and MMP2 and reduces in vitro melanoma cell growth migration and invasion. purity: 98%
TARGETMOL CHEMICALS INC XR-11576 HCL 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. XR-11576 HCl is a novel orally active dual topoisomerase I and II inhibitor with antitumor activity.
Cayman Chemical TopIramate-d12 10mg
An orally bioavailable potent and selective EP4 receptor antagonist (IC50 16.3 nM in a human EP4 functional assay) selective for EP4 with IC50 values of 2.4 1890 20000 and 20000 nM for binding to human EP4 EP2 EP1 and EP3 respectively has potent binding affinity for human rat and dog EP4 (Kis 0.97 6.1 and 38 nM respectively suppresses PGE2-induced elevation of intracellular cAMP in vitro (pA2 1.1 nM) reduces carrageenan-induced mechanical hyperalgesia in rats in a dose-dependent manner