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RMC-6236 is a First-in-Class, non-covalent, oral, potent, and RAS-Selective Tri-Complex RASMULTI(ON) Inhibitor with activity across a diverse spectrum of RAS mutants, including KRASG12V and KRASG12D (
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Ertugliflozin (MK-8835 PF-04971729) is a potent and selective sodium-dependent glucose cotransporter 2 inhibitor with IC50 values of 0 877 nM for h-SGLT2 and 1000-fold higher for h-SGLT1
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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. GKI-1 HCl is a Greatwall (GWL) kinase inhibitor that inhibits hGWLFL and hGWL-KinDom.The inhibitory effect of GKI-1 HCl on ROCK1 is more significant.
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Also available in 1 mL, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associated with hepatic injury and largely when used in combination with other anticonvulsant medications. Purity 98%
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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SRI-37330 HCl(EX-A5854) an anti-diabetic drug is an orally bioavailable inhibitor of thioredoxin-interacting protein (TXNIP) with an IC50 of 0 64 M for TXNIP expression in INS-1 cells Its treatment inhibits glucagon secretion and function decreases hepatic glucose production and reverses hepatic steatosis
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Also available in 1 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Lintopride HCl is a 5HT-4 antagonist. Purity 98.42%
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Topiramate (CAS 97240-79-4) is an anticonvulsant compound widely investigated for its interactions with multiple neuronal ion channels and neurotransmitter receptors including AMPA kainate and NMDA glutamate receptors as well as GABA A receptors and voltage-gated Na channels In vitro studies demonstrate that at submicromolar concentrations (IC 0 5 M) topiramate selectively inhibits GluR5-containing kainate receptor-mediated excitatory synaptic currents in rat basolateral amygdala neurons and partially attenuates AMPA receptor-mediated responses Electrophysiological assays in cortical slices reveal that topiramate modulates persistent Na currents and shifts steady-state inactivation In animal models topiramate confers dose-dependent neuroprotection in ischemic stroke and elevates seizure thresholds supporting its utility for mechanistic studies of epilepsy and neuroprotection
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Davercin (erythromycin cyclocarbonate) is a semi-synthetic macrolide derivative of erythromycin used as a research reagent. It is reported to inhibit bacterial protein synthesis by binding the 50S ribosomal subunit and shows activity against Gram-positive and some Gram-negative organisms, making it useful for microbiology and antibiotic studies.
Macrolide antibiotic derivative active against Gram-positive and some Gram-negative bacteria.
Inhibits protein synthesis through 50S ribosomal binding.
Suitable as a reference standard or reagent in microbiology and antibiotic research.
Provided in small quantities for preparing concentrated stock solutions (for example, 1 mg, 5 mg).
Characterized by CAS 55224-05-0 and molecular formula C38H65NO14.
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Davercin (erythromycin cyclocarbonate) is a macrolide antibiotic derivative of erythromycin used as a research compound. It inhibits bacterial protein synthesis and is active against Gram-positive and some Gram-negative microorganisms. Supplied as a powder, it is intended for in vitro antibacterial studies and medicinal chemistry research.
Macrolide antibiotic derivative suitable for research use.
Inhibits bacterial protein synthesis by targeting the 50S ribosomal subunit.
Active against Gram-positive and some Gram-negative microorganisms.
Supplied as a powder for flexible formulation and dosing.
Defined storage conditions to maintain stability.
Available in small quantities tailored for laboratory studies.
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Davercin (erythromycin cyclocarbonate) is a semi-synthetic macrolide antibiotic derivative used in research to study antibacterial activity and mechanisms of protein synthesis inhibition. It is active primarily against Gram-positive organisms and some Gram-negative strains, and is provided as a characterized reagent for microbiology and pharmacology assays.
Derivative of erythromycin with macrolide activity.
Active against Gram-positive and some Gram-negative microorganisms.
Useful for research on bacterial protein synthesis inhibition.
Characterized chemically: formula C38H65NO14, molecular weight 759.92 g/mol.
Supplied in small research quantities suitable for assay development and characterization.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Davercin (erythromycin cyclocarbonate) is a semi-synthetic derivative of erythromycin used as an antibacterial research reagent. It inhibits bacterial protein synthesis and is active against Gram-positive and some Gram-negative organisms. Supplied as a solid for laboratory studies and analytical reference.
Derivative of erythromycin with antibacterial activity.
Active against Gram-positive and some Gram-negative organisms.
High purity (98.0%).
Molecular weight 759.92 g/mol and formula C38H65NO14.
White to off-white solid suitable for laboratory use.
Available in small research quantities such as 25 MG.
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