Dithiolanes
![Sigma Aldrich 3-(4-Chloro-3-methylphenoxy)-8-[(dipropylamino)methyl]-7-hydroxy-2-(trifluoromethyl)-4H-chromen-4-one](https://assets.fishersci.com/TFS-Assets/CCG/Sigma-Aldrich/product-images/5f6b3e48-37fb-41f4-b6e8-5b63609bed62.jpg-250.jpg)
Sigma Aldrich 3-(4-Chloro-3-methylphenoxy)-8-[(dipropylamino)methyl]-7-hydroxy-2-(trifluoromethyl)-4H-chromen-4-one
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
ALADDIN SCIENTIFIC CORPORATION DL-Thioctic acid, 100g
a-Lipoic acid (LA) a nutritional component found in vegetables and meat has both antioxidant and oxidant properties LA exerts therapeutic potential to many diseases like liver cirrhosis heavy metal poisoning and diabetic polyneuropathy LA exerts apoptotic potential in cancer cells either by oxidative stress related pathway or by activation of caspases DL-Thioctic acid acid has been used in in vitro lipoylation studies and in the pyruvate dehydrogenase complex (PDC)-pyruvate dehydrogenase kinase (PDHK) functional assay It has also been used to investigate its antioxidative effect on developing cerebellum of rats exposed to arsenic during postnatal periodDL-Thioctic acid can reinstate endothelial activities and alleviate oxidative stress in high-fat fed diabetic rats It has also been used to analyze ROS production in astrocytes
Medchemexpress LLC MRT-2359 | 2803881-11-8 | C22H17F4N3O6 | 25 MG
MRT-2359 is a potent, orally active, and selective GSPT1 depressant (IC50: >30 nM and <300 nM) that specifically induces apoptosis dependent on protein translation. It exhibits significant anti-proliferative activity in various cancer cell lines, particularly MYC-driven cell lines like non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) with high N-Myc or L-Myc expression, making it suitable for cancer research.
- Potent, orally active, and selective GSPT1 depressant
- Specifically induces apoptosis dependent on protein translation
- Significant anti-proliferative activity in MYC-driven cancer cell lines
- Effective against non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC)
- Inhibits the growth of drug-resistant NSCLC and SCLC cells
- Reduces N-Myc protein expression and tumor size
- Active against prostate cancer
Sigma Aldrich Fine Chemicals Biosciences Alpha Lipoic Acid1G
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Sigma Aldrich Fine Chemicals Biosciences Thioctic acid European Pha
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.for further information and support please go to the website of the issuing Pharmacopoeia.
Chem-Impex International, Inc. 5-Carboxyfluorescein | MFCD00036874 | 250MG
5-Carboxyfluorescein, MFCD00036874, 250MG
Medchemexpress LLC Α-Lipoic acid (Standard) | 1077-28-7 | 206.33 | 100 MG
Α-Lipoic acid (Standard) | 1077-28-7 | 206.33 | 100 MG
Medchemexpress LLC Α-Lipoic acid sodium | 2319-84-8 | 228.31 | 5 G
α-Lipoic Acid sodium is an antioxidant that serves as an essential cofactor of mitochondrial enzyme complexes. It inhibits NF-κB-dependent HIV-1 LTR activation and induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells.
- Serves as an antioxidant
- Essential cofactor of mitochondrial enzyme complexes
- Inhibits NF-κB-dependent HIV-1 LTR activation
- Induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells
- Supports formation of self-assembled nanoaggregates for improved antitumor efficacy
Medchemexpress LLC 4-Hydroxyisophthalic acid | 636-46-4 | 99.51% | C8H6O5 | 100 MG
4-Hydroxyisophthalic acid is a compound known for its antioxidant properties. It functions by activating key antioxidant enzymes such as catalase (CAT) and superoxide dismutase (SOD), and by scavenging free radicals. This compound also enhances neuronal function through the activation of AChE and BChE, which can lead to improvements in neurobehavioral defects induced by Tau protein and can ameliorate circadian rhythm disorders.
- Activates antioxidant enzymes (catalase CAT and superoxide dismutase SOD)
- Scavenges free radicals
- Exhibits antioxidant properties
- Activates AChE and BChE
- Enhances neuronal function
- Improves Tau-induced neurobehavioral defects
- Ameliorates circadian rhythm disorders in fruit flies
Chem-Impex International, Inc. 5-Carboxyfluorescein | MFCD00036874 | 1G
5-Carboxyfluorescein, MFCD00036874, 1G