FTIDC is an orally active, noncompetitive, selective allosteric antagonist of the metabotropic glutamate receptor 1 (mGluR1). It shows potent antagonistic activity and similar pharmacology across human, mouse, and rat recombinant receptors. Supplied for research use only, it is intended for in vitro and in vivo pharmacology and signaling studies.
- Selective allosteric mGluR1 antagonist
- Potent activity (IC50 5.8 nM for human mGluR1a)
- Cross-species activity (human, mouse, and rat)
- High purity (99.3%)
- Supplied as small solid quantities or 10 mM solution in DMSO
- Suitable for in vitro and in vivo pharmacology studies