Furofurans
Medchemexpress LLC Astragaloside II | 84676-89-1 | 827.01 | 100 MG
Astragaloside II is an orally active Cycloartane-type triterpene glycoside extracted from *Astragalus membranaceus*. It is used in the research of diseases such as liver cancer, osteoporosis, immunosuppressive diseases, and ulcerative colitis. It functions by inhibiting autophagy, decreasing pro-inflammatory cytokines (IL-6, IL-1β), HIF-α, p-p65, and p-IκB, and increasing superoxide dismutase (SOD). It also regulates immunity and reduces inflammatory responses.
- Promotes cell viability of rat primary osteoblasts.
- Enhances proliferation of primary splenocytes.
- Sensitizes cells to 5-fluorouracil-induced cell death.
- Inhibits levels of HIF-α, p-p65, and p-IκB, demonstrating an anti-inflammatory effect.
- Alleviates symptoms of DSS-induced ulcerative colitis in mice.
- Reduces DAI score and prevents body weight loss in vivo.
- Increases colon length and superoxide dismutase in colon tissues.
Medchemexpress LLC Canrenone (Aldadiene) | 976-71-6 | 99.6% | 100 MG
Canrenone (Aldadiene) is an aldosterone antagonist extensively used as a diuretic agent. It inhibits the production of eortieosterone, 18-hydroxydesoxyeortieosterone, 18-hydroxycorticosterone, and aldosterone in a dose-dependent manner. Canrenone also reduces platelet-derived growth factor-induced cell proliferation and motility, and inhibits the activity of the Na+/H+ exchanger 1 induced by platelet-derived growth factor. It is the principal active metabolite of Spironolactone.
- Aldosterone antagonist
- Endogenous metabolite
- Solid appearance
- White to light yellow color
- Steroid structure classification
- Used as a diuretic agent
- Inhibits the production of several corticosteroids
- Reduces cell proliferation and motility induced by platelet-derived growth factor
- Inhibits Na+/H+ exchanger 1 activity
Sigma Aldrich Fine Chemicals Biosciences Terazosin impurity E European Pharmacopoeia (EP) Reference Standard | 102839-00-9 |
Terazosin impurity E European Pharmacopoeia (EP) Reference Standard | Mol Wt: 492.53 | 102839-00-9 |
Medchemexpress LLC (32-carbonyl)-RMC-5552 | 2382768-55-8 | 95.0% | 1776.11 | C93H134N10O24 | 5 MG
(32-Carbonyl)-RMC-5552 is a small-molecule research inhibitor of the mechanistic target of rapamycin (mTOR) that potently inhibits phosphorylation of mTORC1 and mTORC2 substrates. It is intended for biochemical and cellular studies of PI3K/Akt/mTOR signaling and is supplied with analytical characterization for research use.
- Potent dual inhibition of mTORC1 and mTORC2.
- Useful in biochemical and cellular pharmacology studies.
- Characterized molecular properties and CAS identifier for traceability.
- Available as small-scale dry packs and as a DMSO solution for convenient dosing.
- Includes analytical data to support quality control.
Medchemexpress LLC HY-111643 10mg Medchemexpress, 6-Amino-5-azacytidine CAS:105331-00-8 Purity:>98%
Medchemexpress, HY-111643 10mg 6-Amino-5-azacytidine CAS:105331-00-8 6-Amino-5-azacytidine inhibits the growth of bacteria E. coli [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-B0739 100mg Medchemexpress, Citicoline CAS:987-78-0 Purity:>98%
Medchemexpress, HY-B0739 100mg Citicoline CAS:987-78-0 Citicoline (Cytidine diphosphate-choline) is an intermediate in the synthesis of phosphatidylcholine, a component of cell membranes. Citicoline exerts neuroprotective effects. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-111453 5mg Medchemexpress, AZD7594 CAS:1196509-60-0 Purity:>98%
Medchemexpress, HY-111453 5mg AZD7594 CAS:1196509-60-0 AZD7594 is a potent selective nonsteroidal glucocorticoid receptor modulator, with an IC50 of 0.9 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-N6872 5mg Medchemexpress, Actein CAS:18642-44-9 Purity:>98%
Medchemexpress, HY-N6872 5mg Actein CAS:18642-44-9 Actein is a triterpene glycoside isolated from the rhizomes of Cimicifuga foetida. Actein suppresses cell proliferation, induces autophagy and apoptosis through promoting ROS/JNK activation, and blunting AKT pathway in human bladder cancer. Actein has little toxicity in vivo. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-I0513 1mg Medchemexpress, Sofosbuvir impurity N CAS:1394157-34-6 Purity:>98%
Medchemexpress, HY-I0513 1mg Sofosbuvir impurity N CAS:1394157-34-6 Sofosbuvir impurity N, an diastereoisomer of sofosbuvir, is the impurity of sofosbuvir. Sofosbuvir (PSI-7977) is an inhibitor of HCV RNA replication, demonstrates potent anti-hepatitis C virus activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-15005B 1mg Medchemexpress, Sofosbuvir impurity C CAS:1496552-28-3 Purity:>98%
Medchemexpress, HY-15005B 1mg Sofosbuvir impurity C CAS:1496552-28-3 Sofosbuvir impurity C is the less active impurity of Sofosbuvir, Sofosbuvir is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-N0659 5mg Medchemexpress, Jujuboside A CAS:55466-04-1 Purity:>98%
Medchemexpress, HY-N0659 5mg Jujuboside A CAS:55466-04-1 Jujuboside A is a glycoside extracted from Semen Ziziphi Spinosae, a Chinese herbal medicine used to treat insomnia and anxiety. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-15005 100mg , PSI-7977 GS 7977;sofosbuvir CAS:1190307-88-0 Purity:98%
Medchemexpress, HY-15005 100mg PSI-7977 GS 7977;sofosbuvir CAS:1190307-88-0 Formula:C22H29FN3O9P EC50: 92±5 nM (HCV) Purity:98% PSI-7977 is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus ( HCV ) activity. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Selleck Chemical LLC Mericitabine-E0097-5MG
Mericitabine (RG 7128 R-7128 PSI 6130 diisobutyrate) is a nucleoside inhibitor of the HCV NS5B polymerase that acts as an RNA chain terminator and prevents elongation of RNA transcripts during replication
Apexbio Technology LLC Cantharidin 10mM (in 1mL DMSO)
Cantharidin is a naturally occurring terpenoid compound known to function as a potent and selective inhibitor of serine/threonine protein phosphatases particularly protein phosphatase 2A (PP2A) and protein phosphatase 1 (PP1) By inhibiting these enzymes cantharidin disrupts the regulation of numerous cellular processes including cell cycle progression apoptosis and signal transduction pathways This molecule has been widely utilized in research to investigate phosphatase-mediated signaling mechanisms and to explore its potential role in modulating cancer cell proliferation and death Cantharidin serves as a valuable tool for dissecting the functional roles of PP1 and PP2A in various biological systems
Medchemexpress LLC Timosaponin C | 185432-00-2 | 5 MG
Timosaponin C is isolated from Rhizoma Anemarrhenae. It shows weaker NO inhibition in N9 microglial cells.
- Isolated from Rhizoma Anemarrhenae.
- Shows weaker NO inhibition in N9 microglial cells.
- Appearance: White to off-white solid.