Furofurans
Medchemexpress LLC Jujuboside A | 55466-04-1 | 1207.35 | 50 MG
Jujuboside A is a glycoside extracted from Semen Ziziphi Spinosae, a Chinese herbal medicine traditionally used to address insomnia and anxiety. It appears as a white to off-white solid and its structure is classified under Terpenoids and Triterpenes. It is initially sourced from plants like Actaea dahurica Turcz. ex Fisch. & C. A. Mey. and plants from the Rhamnaceae family.
- Acts as an agonist for the GABA receptor.
- Targets mTOR, PI3K, and Akt pathways.
- Increases total sleep and REM sleep during daytime.
- Increases total sleep and NREM sleep during nighttime.
- Neuroprotective agent against behavioral disorders in dementia mouse models.
- Mitigates learning and memory impairment.
- Reduces Aβ1-42 levels in the hippocampus.
- Protects H9C2 cells from isoproterenol-induced injury.
Medchemexpress LLC Astragaloside II | 84676-89-1 | 827.01 | 50 MG
Astragaloside II is an orally active Cycloartane-type triterpene glycoside extracted from Astragalus membranaceus. It inhibits Autophagy, decreases pro-inflammatory cytokines (IL-6, IL-1β), HIF-α, p-p65, p-IκB, and increases SOD. It regulates immunity and reduces inflammatory responses. This compound can be used in research for diseases like liver cancer, osteoporosis, immunosuppressive diseases, and ulcerative colitis.
- Purity: 99.45%
- Molecular weight: 827.01
- Formula: C43H70O15
- Appearance: Solid
- Color: White to off-white
- Structure classification: Terpenoids, Triterpenes
- Initial source: Plants, Leguminosae, Astragalus membranaceus var. mongholicus (Bunge)P.K.Hsiao
Medchemexpress LLC Astragaloside I | 84680-75-1 | 869.04 | 50 MG
Astragaloside I, one of the main active ingredients in Astragalus membranaceus, possesses osteogenic properties. It stimulates osteoblast differentiation through activating the Wnt/β-catenin signaling pathway.
- Main active ingredient in Astragalus membranaceus.
- Has osteogenic properties.
- Stimulates osteoblast differentiation by activating the Wnt/β-catenin signaling pathway.
- Upregulates expression of β-catenin, Runx2, BGP, and OPG, RANKL (osteogenesis marker genes) in MC3T3-E1 cells at concentrations of 10-40 μM.
- No obvious cytotoxic effect observed in MC3T3-E1 cells at 10-40 μM.
- Purity: 99.81%.
- Appearance: Solid.
- Color: White to off-white.
Medchemexpress LLC HY-N1374 5mg Medchemexpress, Magnolin CAS:31008-18-1 Purity:>98%
Medchemexpress, HY-N1374 5mg Magnolin CAS:31008-18-1 Magnolin, a major component of Magnolia flos (Shin-Yi), inhibits the Ras/ERKs/RSK2 signaling axis by targeting the active pocket of ERK1 and ERK2 with IC 50 s of 87 nM and 16.5 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Isosorbide dinitrate | 87-33-2 | MFCD00868238 | 99.9% | 236.14 | C6H8N2O8 | 10 MG
Isosorbide dinitrate is a nitric oxide (NO) donor used as a research reagent and analytical standard for studies of vasodilation, myocardial infarction, and cardiac remodeling. It is supplied as a high-purity solid suitable for in vitro and analytical applications.
- High purity (99.9%).
- Chemical formula C6H8N2O8; molecular weight 236.14.
- CAS number 87-33-2.
- Soluble in DMSO (100 mg/mL); ultrasonic agitation recommended.
- Store protected from light at 4°C; in solvent, -80°C up to 6 months or -20°C up to 1 month.
- Available as solid packs (5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg) and as 10 mM solutions in DMSO.