Imidazopyridines
![Medchemexpress LLC 4-Oxazolecarboxamide, N-[6-[(2-methoxyethyl)methylamino]-3-pyridinyl]-2-phenyl-5-(trifluorom | 939375-07-2 | 99.9% | 420.39 | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000393984.png-250.jpg)
Medchemexpress LLC 4-Oxazolecarboxamide, N-[6-[(2-methoxyethyl)methylamino]-3-pyridinyl]-2-phenyl-5-(trifluorom | 939375-07-2 | 99.9% | 420.39 | 100 MG
DGAT1-IN-3 is a potent, selective, and orally bioavailable inhibitor of DGAT-1. It can be used for research on obesity, dyslipidemia, and metabolic syndrome.
- Potent, selective, and orally bioavailable inhibitor of DGAT-1.
- Inhibits human DGAT-1 with an IC50 of 38 nM.
- Inhibits rat DGAT-1 with an IC50 of 120 nM.
- Supports research into obesity.
- Supports research into dyslipidemia.
- Supports research into metabolic syndrome.
- Reduces cumulative body weight gain in DIO rats.
- Reduces weight gain and plasma triglycerides.
- Improves lipid profiles.
![eMolecules 2-BROMOIMIDAZO[1,2-A]PYRIDINE-7-CARBOXYLIC ACID | 1784089-67-3 | MFCD28404701 | 0.25g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502182184.JPG-250.jpg)
eMolecules 2-BROMOIMIDAZO[1,2-A]PYRIDINE-7-CARBOXYLIC ACID | 1784089-67-3 | MFCD28404701 | 0.25g
AstaTech | 2-BROMOIMIDAZO[1,2-A]PYRIDINE-7-CARBOXYLIC ACID | 0.25g | 273167239 | 73516 | 95.000 | 1784089-67-3 | MFCD28404701 | 241.044 | C8H5BrN2O2
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Medchemexpress LLC 3-Cl-Pyridine-amide-acrylaldehyde-piperazine | 99.3% | 294.74 | 50 MG
3-Cl-Pyridine-amide-acrylaldehyde-piperazine is a synthetic intermediate of LO-4-25. LO-4-25 is an androgen receptor (AR) DNA binding domain ligand linked via a linker to the truncated fumaramide handle. This product shows robust degradation of both AR and AR-V7 in 22Rv1 cells.
- Synthetic intermediate.
- Degrades androgen receptor (AR) and AR-V7 in 22Rv1 cells.
- For research use only.
- Relevant to cancer research.
Chem-Impex International, Inc. Imidazo[1,2-a]pyridine-6-boronic acid | 913835-63-9 | MFCD06739225 | 1G
Imidazo[1,2-a]pyridine-6-boronic acid, 913835-63-9, MFCD06739225, 1G
![eMolecules (6-Chloro-imidazo[1,2-a]pyridin-2-ylmethyl)-methyl-amine | 554407-29-3 | MFCD03970805 | 5g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502156169.JPG-250.jpg)
eMolecules (6-Chloro-imidazo[1,2-a]pyridin-2-ylmethyl)-methyl-amine | 554407-29-3 | MFCD03970805 | 5g
J & W PharmLab LLC | (6-Chloro-imidazo[1,2-a]pyridin-2-ylmethyl)-methyl-amine | 5g | 289354608 | 68R0212 | 96.000 | 554407-29-3 | MFCD03970805 | 195.650 | C9H10ClN3
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Medchemexpress LLC CXCR7 antagonist-1 | 2990472-61-0 | 99.4% | C21H20ClFN6O | 10MG
CXCR7 antagonist-1 hydrochloride is a small-molecule antagonist of the chemokine receptor CXCR7 that inhibits binding of the chemokines SDF-1 (CXCL12) and I-TAC (CXCL11). It is supplied as the hydrochloride salt for research use in studies of tumor cell proliferation, tumor formation, and inflammatory disease pathways.
- Antagonist of the CXCR7 chemokine receptor.
- Inhibits SDF-1 (CXCL12) and I-TAC (CXCL11) binding to CXCR7.
- Provided as the hydrochloride salt in a solid form.
- High purity (99.4%).
- Supplied in small research-scale quantities suitable for in vitro assays.
Medchemexpress LLC Estrogen receptor modulator 1 | 63676-22-2 | 99.91% | 242.29 | 500 MG
Estrogen receptor modulator 1 (compound 18) is an orally active and selective estrogen receptor modulator (SERM), with a pIC50 of 0.46. It induces regression of Tamoxifen-resistant, hormone independent xenograft tumors.
- Orally active and selective estrogen receptor modulator (SERM).
- Induces regression of Tamoxifen-resistant, hormone independent xenograft tumors.
- Inhibits T47D:A18/PKCα and T47D:A18-TAM1 colony formation at 100 nM for 10 days.
- Significantly inhibits the growth of MCF-7:5C cells and induces apoptosis at 100 nM for 9 days.
- Appearance: Solid, White to off-white.
- Shipping: Room temperature in continental US; may vary elsewhere.
- Storage: Powder at -20°C for 3 years; In solvent at -80°C for 6 months, or -20°C for 1 month.
eMolecules Pharmablock 6-bromo-2-methyl-imidazo[1 2-a]pyrimidine 50mg 788526987 PBT2348 0 000 1111638-05-1 MFCD12024554 212 050 C7H6BrN3
Pharmablock 6-bromo-2-methyl-imidazo[1 2-a]pyrimidine 50mg 788526987 PBT2348 0 000 1111638-05-1 MFCD12024554 212 050 C7H6BrN3
Medchemexpress LLC (E)-5-((8-methoxy-2-methylquinolin-4-yl)amino)-N'-(4-(methylthio)benzylidene)-1H-indole-2-carbohydr | 2469975-55-9 | MFCD34167507 | 98.6% | 495.60 g/mol | C28H25N5O2S | 5 MG
Nur77 modulator 1 is a small-molecule ligand that binds the nuclear receptor Nur77 (KD = 3.58 μM). It up-regulates Nur77 expression, alters subcellular localization, induces Nur77-dependent endoplasmic reticulum stress and autophagy, and can lead to apoptosis; reported anti-hepatoma activity. For research use only.
- Binds Nur77 with a KD of 3.58 μM.
- Up-regulates Nur77 expression and alters subcellular localization.
- Induces ER stress and autophagy, leading to apoptosis.
- Reported anti-hepatoma activity in preclinical studies.
- High purity solid suitable for in vitro assays; soluble in DMSO.
- Available in multiple pack sizes for research workflows.