Imidazopyridines
Medchemexpress LLC IL-17A modulator-2 | 2748749-47-3 | 98.4% | 577.63 | C33H31N5O5 | 5 MG
IL-17A modulator-2 is a small-molecule research compound that inhibits the biological activity of interleukin-17A. Reported from patent WO2021239743 (example 27), it is intended for use in preclinical studies investigating immune-related, autoimmune, cancer, and neurodegenerative disorders.
- Inhibits interleukin-17A with a reported pIC50 of 8.3.
- High purity suitable for research applications (≈98.4%).
- Molecular weight 577.63; formula C33H31N5O5.
- Available in small quantities appropriate for in vitro assays.
- Reportedly derived from a patent example, supporting reproducible synthesis.
- Intended for research use only; not for human therapeutic use.
Medchemexpress LLC Olprinone Hydrochloride | 119615-63-3 | 99.9% | C14H11ClN4O | 100 MG
Olprinone Hydrochloride is a potent phosphodiesterase (PDE) 3 inhibitor, with IC50s of 0.35 μM for PDE3. It is used for the research of heart failure due to its positive inotropic and vasodilative effects, and also exhibits anti-inflammatory activity.
- Potent phosphodiesterase 3 inhibitor
- Exhibits positive inotropic and vasodilative effects
- Shows anti-inflammatory activity
- Suitable for heart failure research
- Reduces myocardial injury in vivo
Medchemexpress LLC HY-112154 5mg Medchemexpress, CXCR7 modulator 2 CAS: Purity:>98%
Medchemexpress, HY-112154 5mg CXCR7 modulator 2 CAS: CXCR7 modulator 2 is a modulator of C-X-C Chemokine Receptor Type 7 ( CXCR7 ), with a K i of 13 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
![Medchemexpress LLC 4-Oxazolecarboxamide, N-[6-[(2-methoxyethyl)methylamino]-3-pyridinyl]-2-phenyl-5-(trifluoromethyl)- | 939375-07-2 | 99.9% | 420.39 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000394191.png-250.jpg)
Medchemexpress LLC 4-Oxazolecarboxamide, N-[6-[(2-methoxyethyl)methylamino]-3-pyridinyl]-2-phenyl-5-(trifluoromethyl)- | 939375-07-2 | 99.9% | 420.39 | 5 MG
DGAT1-IN-3 is a potent, selective, and orally bioavailable inhibitor of DGAT-1, with IC50s of 38 nM for human DGAT-1 and 120 nM for rat DGAT-1. It can be used for research on obesity, dyslipidemia, and metabolic syndrome.
- Potent, selective, and orally bioavailable inhibitor of DGAT-1.
- IC50s: 38 nM (human DGAT-1); 120 nM (rat DGAT-1).
- Reduces weight gain and plasma triglycerides, and improves lipid profile in animal models.
- Exhibits good oral bioavailability (77%) and a maximum exposure level in plasma (Cmax) of 24 μM (50 mg/kg; p.o).
- Exhibits terminal elimination half-lives (1.95 h) and low clearance (13.5 mL/min/kg) (5 mg/kg; i.v).
- Appearance: solid, light yellow to yellow color.
Medchemexpress LLC HY-100414 1mg Medchemexpress, Soraprazan CAS:261944-46-1 Purity:>98%
Medchemexpress, HY-100414 1mg Soraprazan CAS:261944-46-1 Soraprazan (BYK61359) is a reversible, and fast-acting inhibitor of gastric H + /K + ATPase . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Il-17a modulator-1 | 2748749-29-1 | 98.8% | 561.63 g·mol⁻¹ | C33H31N5O4 | 5 MG
IL-17A modulator-1 is a small-molecule research compound that inhibits interleukin-17A (IL-17A) signaling. Reported in patent WO2021239743 (example 9), the compound exhibits potent IL-17A inhibitory activity (pIC50 ≈ 8.2) and is intended for in vitro and preclinical studies of immune-mediated and autoimmune diseases, oncology, and neurodegenerative disorder models.
- Potent IL-17A inhibitory activity (pIC50 ≈ 8.2).
- Suitable for in vitro and preclinical research applications.
- High reported purity for consistent experimental results.
- Available in multiple small-molecule pack sizes for dose-ranging studies.
- Provided with analytical data (COA, LCMS, 1H NMR) for quality control.
Medchemexpress LLC CXCR7 modulator 1 (compound 25) | 2231812-31-8 | 99.5% | 914.07 | C48H57F2N7O7S | 100 MG
CXCR7 modulator 1 is a potent, orally bioavailable peptoid-hybrid small molecule that modulates the chemokine receptor CXCR7 (reported Ki = 9 nM). It is intended for research use in studies of GPCR signaling and immunology/inflammation.
- Potent CXCR7 modulator with reported Ki of 9 nM.
- Orally bioavailable peptoid-hybrid small molecule.
- Peptoid-hybrid scaffold suitable for medicinal chemistry studies.
- High purity (99.5%) for research applications.
- Molecular weight 914.07, molecular formula C48H57F2N7O7S.
- Suitable for GPCR signaling and immunology or inflammation research.
Medchemexpress LLC CXCR7 antagonist-1 | 2990472-61-0 | 99.4% | C21H20ClFN6O | 10MG
CXCR7 antagonist-1 hydrochloride is a small-molecule antagonist of the chemokine receptor CXCR7 that inhibits binding of the chemokines SDF-1 (CXCL12) and I-TAC (CXCL11). It is supplied as the hydrochloride salt for research use in studies of tumor cell proliferation, tumor formation, and inflammatory disease pathways.
- Antagonist of the CXCR7 chemokine receptor.
- Inhibits SDF-1 (CXCL12) and I-TAC (CXCL11) binding to CXCR7.
- Provided as the hydrochloride salt in a solid form.
- High purity (99.4%).
- Supplied in small research-scale quantities suitable for in vitro assays.
Selleck Chemical LLC IRAK inhibitor 6 S2039-2mg
IRAK inhibitor 6 is a selective Interleukin-1 receptor-associated kinase 4(IRAK4) inhibitor with IC50 of 0 16 M
Medchemexpress LLC HY-12425 5mg Medchemexpress, DGAT1-IN-1 CAS:1449779-49-0 Purity:>98%
Medchemexpress, HY-12425 5mg DGAT1-IN-1 CAS:1449779-49-0 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Elsulfavirine (R-1206) | 868046-19-9 | 99.9% | 629.28 | 100 MG
Elsulfavirine (R-1206) | 868046-19-9 | 99.9% | 629.28 | 100 MG
