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Imidazopyridines

Organic heterocyclic compounds that contain an imidazole ring fused to a pyridine ring. Imidazole is five-membered ring with three carbon atoms and two nitrogen atoms; pyridine is a six-membered ring with five carbon atoms and one nitrogen atom.

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Medchemexpress LLC (E)-5-((8-methoxy-2-methylquinolin-4-yl)amino)-N'-(4-(methylthio)benzylidene)-1H-indole-2-carbohydr | 2469975-55-9 | MFCD34167507 | 98.6% | 495.60 g/mol | C28H25N5O2S | 5 MG
SDP

Nur77 modulator 1 is a small-molecule ligand that binds the nuclear receptor Nur77 (KD = 3.58 μM). It up-regulates Nur77 expression, alters subcellular localization, induces Nur77-dependent endoplasmic reticulum stress and autophagy, and can lead to apoptosis; reported anti-hepatoma activity. For research use only.

  • Binds Nur77 with a KD of 3.58 μM.
  • Up-regulates Nur77 expression and alters subcellular localization.
  • Induces ER stress and autophagy, leading to apoptosis.
  • Reported anti-hepatoma activity in preclinical studies.
  • High purity solid suitable for in vitro assays; soluble in DMSO.
  • Available in multiple pack sizes for research workflows.

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