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Medchemexpress LLC (E)-5-((8-methoxy-2-methylquinolin-4-yl)amino)-N'-(4-(methylthio)benzylidene)-1H-indole-2-carbohydr | 2469975-55-9 | MFCD34167507 | 98.6% | 495.60 g/mol | C28H25N5O2S | 5 MG

Supplier: Medchemexpress LLC HY1313645MG
Nur77 modulator 1 is a small-molecule ligand that binds the nuclear receptor Nur77 (KD = 3.58 μM). It up-regulates Nur77 expression, alters subcellular localization, induces Nur77-dependent endoplasmic reticulum stress and autophagy, and can lead to apoptosis; reported anti-hepatoma activity. For research use only.
- Binds Nur77 with a KD of 3.58 μM.
- Up-regulates Nur77 expression and alters subcellular localization.
- Induces ER stress and autophagy, leading to apoptosis.
- Reported anti-hepatoma activity in preclinical studies.
- High purity solid suitable for in vitro assays; soluble in DMSO.
- Available in multiple pack sizes for research workflows.
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