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Imidazopyridines

Organic heterocyclic compounds that contain an imidazole ring fused to a pyridine ring. Imidazole is five-membered ring with three carbon atoms and two nitrogen atoms; pyridine is a six-membered ring with five carbon atoms and one nitrogen atom.

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Medchemexpress LLC Estrogen receptor modulator 1 | 63676-22-2 | 99.91% | 242.29 | 500 MG
SDP

Estrogen receptor modulator 1 (compound 18) is an orally active and selective estrogen receptor modulator (SERM), with a pIC50 of 0.46. It induces regression of Tamoxifen-resistant, hormone independent xenograft tumors.

  • Orally active and selective estrogen receptor modulator (SERM).
  • Induces regression of Tamoxifen-resistant, hormone independent xenograft tumors.
  • Inhibits T47D:A18/PKCα and T47D:A18-TAM1 colony formation at 100 nM for 10 days.
  • Significantly inhibits the growth of MCF-7:5C cells and induces apoptosis at 100 nM for 9 days.
  • Appearance: Solid, White to off-white.
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Storage: Powder at -20°C for 3 years; In solvent at -80°C for 6 months, or -20°C for 1 month.

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