Imidazopyrimidines
Selleck Chemical LLC IBMX
IBMX (Isobutylmethylxanthine 1-Methyl-3-Isobutylxanthine) is a nonspecific inhibitor of phosphodiesterase (PDE) with IC50 values of 6 5 1 2 26 3 3 9 and 31 7 5 3 M for PDE3 4 and 5 respectively It may enhance the intracellular cAMP levels and also acts as an adenosine (A1) receptor antagonist
Medchemexpress LLC HY-N0814A 250mg Medchemexpress, Phytic acid (dodecasodium salt hydrate) CAS:123408-98-0 Purity:>98%
Medchemexpress, HY-N0814A 250mg Phytic acid (dodecasodium salt hydrate) CAS:123408-98-0 Phytic acid dodecasodium salt hydrate is a phosphorus storage compound of seeds and cereal grains. Phytic acid dodecasodium salt hydrate is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid dodecasodium salt hydrate inhibits the enzymatic superoxide source xanthine oxidase (XO) , and has antioxidative, neuroprotective, anti-inflammatory effects [1] [2] [3] [4] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Xanthine oxidase, bovine milk | 9002-17-9 | 100 U
Xanthine oxidase from bovine milk is a xanthine oxidoreductase enzyme that generates reactive oxygen species (ROS), catalyzes the oxidation of hypoxanthine to xanthine, and further catalyzes the oxidation of xanthine to uric acid.
- This enzyme rapidly and completely depletes hypoxanthine in human erythrocytes.
- It inhibits the growth of Plasmodium falciparum in human erythrocytes in vitro.
- It reduces the viability of postnatal cerebellar granule neurons obtained from 8-day old Sprague-Dawley rat pups.
Medchemexpress LLC Adenine-13C5,15N5 | 95% | 1 MG
Adenine-13C5,15N5 is a 13C-labeled adenine, also known as 6-Aminopurine-13C5,15N5 or Vitamin B4-13C5,15N5. As a purine and one of the four nucleobases in DNA, it is a crucial chemical component of both DNA and RNA. It plays a significant role in biochemistry, particularly in cellular respiration, the formation of ATP and cofactors (NAD and FAD), and protein synthesis.
- Isotope-labeled compound for tracing in drug development.
- Essential component of DNA and RNA.
- Involved in cellular respiration and protein synthesis.
- Suitable for research in cancer.
- Purity (HPLC): 95%.
- Isotopic enrichment: >98%.
- Appearance: White to off-white solid.
Sigma Aldrich Fine Chemicals Biosciences 3-Methyladenine autophagy inhibitor | 5142-23-4 | MFCD00010531 | 100MG
3-Methyladenine autophagy inhibitor | Purity: >=99% (HPLC) | Mol Wt: 149.15 | 5142-23-4 | MFCD00010531 | 100MG
Medchemexpress LLC FAPy-adenine | 5122-36-1 | 99.86% | 153.14 | 1 ML
FAPy-adenine is an oxidized DNA base whose levels show an increased trend in the Alzheimer's disease brain. Oxidized nucleosides serve as biochemical markers for tumors, aging, and neurodegenerative diseases. This compound is able to form pairs with all four canonical nucleic acid bases. For research use only; not sold to patients.
- Oxidized DNA base.
- Increased levels observed in Alzheimer's disease brain.
- Biochemical marker for tumors, aging, and neurodegenerative diseases.
- Forms pairs with all four canonical nucleic acid bases.
Medchemexpress LLC Adenine (6-aminopurine) | 73-24-5 | MFCD00041790 | 99.9% | 135.13 g/mol | C5H5N5 | 10 MG
Adenine (6-aminopurine) analytical standard supplied as a high-purity reference material for research and analytical applications. It appears as a white to off-white crystalline powder and is provided with supporting documentation for analytical use.
- High purity: 99.91%.
- Chemical formula C5H5N5 and molecular weight 135.13 g/mol.
- Suitable as a reference standard for HPLC, LC-MS, and other analytical assays.
- Provided with a certificate of analysis and safety data sheet for traceability.
- Intended for research and analytical use only.
- Available in small quantities for method development and calibration.
Apexbio Technology LLC Adenine 73-24-5 1g
Adenine (73-24-5) is a selective agonist targeting high-affinity adenine receptors It is designed to activate these receptors thereby mediating cellular signaling cascades and regulating diverse physiological and biochemical pathways Adenine exerts its biological activity primarily through receptor-ligand interactions that trigger downstream intracellular signaling Experimental evidence indicates that adenine exhibits receptor activation with IC50 values typically ranging from 50 to 200 nM dependent upon the specific receptor subtype and assay context Based on these pharmacological properties adenine holds research potential in receptor binding assays pharmacological experiments to elucidate receptor function assess signaling mechanisms and investigate therapeutic interventions targeting adenine-responsive pathways