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Organic heterocyclic compounds that contain an imidazole ring fused to a pyrimidine ring. Imidazole is five-membered ring with three carbon atoms and two nitrogen atoms; pyrimidine is a six-membered ring with four carbon atoms and two nitrogen atoms.
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(R)-Lisofylline is the R-enantiomer of lisofylline, a metabolite of pentoxifylline with documented anti-inflammatory activity. It is used as a research compound to probe lipid signaling and immune pathways, including inhibition of lysophosphatidic acid acyltransferase and disruption of IL-12-mediated STAT4 activation.