Indoles and derivatives
eMolecules 2,7-Bis(trifluoromethyl)-9H-carbazole | 1657076-40-8 | | 1g
Synthonix - Stock | 2,7-Bis(trifluoromethyl)-9H-carbazole | 1g | 495873139 | B62654 | | 1657076-40-8 | | 303.207 | C14H7F6N
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Apexbio Technology LLC TAK-875 1000413-72-8 10mM (in 1mL DMSO)
TAK-875 (CAS 1000413-72-8) is a selective orally bioavailable agonist targeting G-protein-coupled receptor 40 (GPR40) a receptor primarily expressed in pancreatic -cells Activation of GPR40 enhances glucose-dependent insulin secretion via free fatty acid signaling In vitro assays demonstrate that TAK-875 exhibits potent agonistic activity toward human GPR40 with minimal cross-reactivity against other related receptors in the free fatty acid receptor family (EC50 10 M) Additionally in vivo studies in glucose-intolerant obese Wistar rats have shown that oral administration of TAK-875 improves glucose tolerance and stimulates insulin release Clinically TAK-875 has been explored as a glucose-dependent insulin secretagogue with once-daily oral dosing potential
1,3,6,8-Tetranitrocarbazole (wetted with ca. 40% Water) (unit weight on dry weight basis) 70.0+%, TCI America™
CAS: 4543-33-3 Molecular Formula: C12H5N5O8 Molecular Weight (g/mol): 347.199 MDL Number: MFCD00022211 InChI Key: JUSWGNJYSBSOFM-UHFFFAOYSA-N PubChem CID: 72755 IUPAC Name: 1,3,6,8-tetranitro-9H-carbazole SMILES: C1=C(C=C2C3=CC(=CC(=C3NC2=C1[N+](=O)[O-])[N+](=O)[O-])[N+](=O)[O-])[N+](=O)[O-]