Lactams
Medchemexpress LLC CD3 epsilon Human 100ug
Recombinant human CD3 epsilon protein supplied as a lyophilized powder, expressed in HEK293 cells and carrying a C-terminal 6xHis tag. The protein is intended for T-cell signaling research, assay development, and biochemical characterization; it offers high purity and low endotoxin to support sensitive in vitro and cell-based assays.
- Lyophilized powder for convenient storage and transport.
- Expressed in HEK293 cells for human-like post-translational modifications.
- C-terminal 6xHis tag facilitates purification and detection.
- Purity greater than 95% as determined by reducing SDS-PAGE.
- Endotoxin level below 1 EU/μg, suitable for sensitive assays.
- Available in 10 μg, 50 μg, 100 μg, and 500 μg sizes.
- Recommended reconstitution at ≥100 μg/mL; refer to lot-specific COA for buffer details.
Medchemexpress LLC Fc epsilon RIA/FCER1A protein, mouse (HEK293, C-hFc) | >85.0% | 5 UG
Recombinant mouse Fc epsilon RI alpha (FCER1A) extracellular domain fused to a C-terminal human Fc, expressed in HEK293 cells and supplied lyophilized. Intended for immunoassays, binding studies, and functional assays involving IgE-FcεRI interactions; documentation including datasheet and COA is available.
Medchemexpress LLC Aztreonam (Standard) | 78110-38-0 | 99.6% | 5 MG
Aztreonam (Standard) is the analytical standard of Aztreonam, intended for research and analytical applications. This synthetic monocyclic beta-lactam antibiotic has a very high affinity for penicillin-binding protein 3 (PBP-3).
- Reference standard supplied assay
- Used in qualitative research experiments
- Used in quantitative research experiments
- Used in methodological research experiments
- Suitable for HPLC
- Suitable for GC
- Suitable for MS
Medchemexpress LLC Aztreonam | 78110-38-0 | MFCD00072145 | 99.6% | 435.43 | C13H17N5O8S2 | 10 MG
Aztreonam (standard) is an analytical reference material containing the monobactam antibiotic aztreonam. Provided at high purity, it is intended for analytical testing, assay calibration, method validation, and quality control in pharmaceutical and biochemical laboratories.
- Analytical reference standard for aztreonam.
- High purity suitable for assay and quality control work.
- Available in small precision pack sizes for analytical use.
- Reported molecular weight 435.43 and formula C13H17N5O8S2.
- Includes CAS number 78110-38-0 for unambiguous identification.
Medchemexpress LLC Acy-957 | 1609389-52-7 | 99.6% | 429.54 g/mol | C24H23N5OS | 50 MG
ACY-957 is an orally active, selective small-molecule inhibitor of histone deacetylase isoforms HDAC1 and HDAC2, used for research into epigenetic regulation. It shows potent activity against HDAC1 and HDAC2, reduced activity against HDAC3, and no measurable inhibition of several class II HDACs. The compound is supplied as a high-purity solid and is available in solution formats for assay use.
- Potent inhibition of HDAC1 and HDAC2.
- High selectivity over HDAC3 and class II HDACs.
- Suitable for in vitro and in vivo formulation protocols.
- High reported purity for reliable experimental results.
- Provided as a solid and as ready-to-use DMSO solutions.
- Documented storage and stability conditions for sample handling.
Selleck Chemical LLC Sulbactam sodium S2551-50mg
Sulbactam sodium (Unasyn CP-45899-2) is an irreversible -lactamase inhibitor
Selleck Chemical LLC Tazobactam S3077-100mg
Tazobactam (Tazobactam acid Tazobactamum) is a -lactamases Inhibitor with antibacterial activity It also inhibits the class D oxacillinase OXA-2 It is used in combination with piperacillin and other -lactam antibiotics to broaden their spectrum and enhance their effect
Medchemexpress LLC Tazobactam | 89786-04-9 | 99.9% | 1 ML
Tazobactam is a potent β-lactamases inhibitor and penicillin antibiotic. It exhibits antibacterial activity and can be used for pneumonia research.
- Potent β-lactamases inhibitor
- Penicillin antibiotic
- Antibacterial activity
- Can be used for pneumonia research
Medchemexpress LLC Sulbactam | 68373-14-8 | 100.0% | 100 MG
Sulbactam is a competitive, irreversible beta-lactamase inhibitor. It exhibits antimicrobial activity against multidrug-resistant (MDR) Acinetobacter calcoaceticus-Acinetobacter baumannii (Acb) complex and possesses a broad spectrum of antibacterial activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria. It is suitable for use as a laboratory chemical and in the manufacture of substances.
- Competitive, irreversible beta-lactamase inhibitor
- Antimicrobial activity against multidrug-resistant (MDR) Acinetobacter calcoaceticus-Acinetobacter baumannii (Acb) complex
- Broad spectrum antibacterial activity
- Solid form, light yellow to yellow in color
- Suitable for laboratory chemical applications
- Melting point: 154-157°C
- Boiling point: 356°C at 760 mmHg
- Flash point: 297.1°C
- For research use only
U.S. Pharmacopeia Sulbactam, 68373-14-8, MFCD00867005, 250mg
Molecular formula C8H11NO5S, Molecular weight 233.24, Melting Point 298.4 - 303.8 °F (148 - 151 °C) (also reported as 170 °C), Synonyms: Penicillanic acid 1,1-dioxide. Cold Shipment Required
Apexbio Technology LLC Tazobactam (sodium salt) 89785-84-2 250mg
Tazobactam sodium salt (CAS 89785-84-2) is a small-molecule inhibitor targeting -lactamases It is designed to irreversibly bind to -lactamases thereby preventing the enzyme-mediated hydrolysis of -lactam antibiotics Tazobactam sodium salt exerts its biological activity primarily through -lactamase inhibition In microbiological assays tazobactam demonstrates intrinsic antibacterial activity against several Acinetobacter strains typically with MIC values of 8 mg/L (range 2 32 mg/L) Based on these pharmacological properties tazobactam sodium salt holds research potential in microbiological assessments and efficacy evaluations of -lactam antibiotic combinations
Medchemexpress LLC Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc | 1799711-31-1 | 98.4% | C30H42N4O11 | 10MG
Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc is a thalidomide-derived E3 ligase ligand-linker conjugate supplied as a solid for research use. The compound features a PEG3 linker and a Boc-protected terminal amine, offered with high reported purity and characterized molecular data, suitable as a synthetic intermediate in chemical biology and PROTAC development.
- High reported purity suitable for synthesis and analysis.
- Characterized molecular formula and molecular weight for experimental planning.
- Boc-protected terminal amine enables selective deprotection and conjugation.
- PEG3 linker provides flexibility and improved solubility in conjugates.
- Available in small milligram quantities for research workflows.
Medchemexpress LLC Thalidomide-5-methyl | 40313-92-6 | MFCD30290642 | 99.9% | 272.26 g·mol-1 | C14H12N2O4 | 5 MG
Thalidomide-5-methyl is a thalidomide-derived cereblon (CRBN) ligand used to recruit the CRBN E3 ligase subunit in chemical biology and targeted protein degradation applications. It is provided as a research-grade small molecule suitable for use as a CRBN-binding moiety in PROTAC synthesis.
- Cereblon (CRBN) ligand for recruiting E3 ligase in PROTAC design.
- High purity suitable for research applications (99.87%).
- Molecular formula C14H12N2O4 and molecular weight 272.26 g·mol-1.
- Supplied in milligram-scale quantities for synthesis and assay development.
- Useful as a modular CRBN-binding building block in chemical biology experiments.
Medchemexpress LLC Thalidomide-4-O-C4-NH2 hydrochloride | 2376990-29-1 | MFCD32705123 | 99.4% | 381.81 | C17H20ClN3O5 | 5 MG
Thalidomide-4-O-C4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate supplied as the hydrochloride salt for use in PROTAC research. It couples a thalidomide-derived cereblon ligand to a four-carbon alkyl linker terminating in a primary amine, enabling conjugation to target-binding moieties. The material is intended for laboratory research use only.
- High purity (99.35%).
- Hydrochloride salt form for handling and stability.
- Molecular weight 381.81.
- Molecular formula C17H20ClN3O5.
- Available in small research quantities (5 mg and up).
- Intended for use in PROTAC design and cereblon-based degrader development.
Medchemexpress LLC Thalidomide-pyrrolidine hydrochloride | 2616553-35-4 | 98.0% | 335.74 g/mol | C15H14ClN3O4 | 25 MG
Thalidomide-pyrrolidine hydrochloride is an E3 ligase ligand (compound 18) used as a cereblon (CRBN) ligand in the synthesis of PROTAC degraders and other bifunctional molecules. It is supplied as an off-white to gray solid with high purity for research use.
- High purity: 98.0%.
- Molecular weight: 335.74 g/mol.
- Molecular formula: C15H14ClN3O4.
- CAS number: 2616553-35-4.
- Physical form: off-white to gray solid.
- Storage: store dry and keep cool; in solution store at -80°C (2 years) or -20°C (1 year).
- Applications: used as an E3 ligase ligand for PROTAC synthesis.