Lactams
Medchemexpress LLC 1H-isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-iodo | 2509137-01-1 | MFCD31735039 | 98.0% | 384.13 | C13H9IN2O4 | 500 MG
Thalidomide-iodo is an iodinated derivative of thalidomide used as an E3 ligase (cereblon) activator for research applications. It is intended as a building block and synthetic intermediate for further derivatization by substitution of the iodine atom.
- E3 ligase activator (cereblon ligand) for targeted protein degradation research.
- Suitable as a synthetic intermediate for iodide substitution and further derivatization.
- High purity: 98.0% (NMR).
- Molecular formula C13H9IN2O4; molecular weight 384.13.
- CAS number 2509137-01-1.
- Appearance: gray to dark gray solid.
- Storage: 4°C, protect from light; in solvent: -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC Thalidomide-5-o-c9-nh2 hydrochloride | 99.6% | 451.94 g·mol⁻1 | C22H30ClN3O5 | 10 MG
Thalidomide-5-O-C9-NH2 hydrochloride is a thalidomide-derived cereblon (CRBN) ligand intended for chemical biology research. Supplied as the hydrochloride salt, it is used as an E3 ligase recruiting moiety in PROTACs and related conjugates. The product is reported with molecular formula C22H30ClN3O5 and molecular weight 451.94 g·mol⁻1.
- High purity: 99.6%.
- Hydrochloride salt form for improved handling and solubility.
- Designed for recruitment of cereblon (CRBN) in PROTAC construction.
- Suitable for synthesis, assay development, and linker conjugation.
- Available in small research pack sizes for laboratory use.
Medchemexpress LLC Thalidomide-5-CH2-NH2 hydrochloride | 1010100-22-7 | MFCD32666042 | 98.6% | 323.73 | C14H14ClN3O4 | 50 MG
Thalidomide-5-CH2-NH2 hydrochloride is a thalidomide-derived cereblon (CRBN) ligand used as an E3 ligase recruiting moiety in PROTAC design and targeted protein degradation research. Supplied as a solid with high purity, it serves as a linker-compatible building block for medicinal chemistry and chemical biology applications.
- High purity suitable for research.
- Solid form, easy to handle and store.
- Compatible with linker conjugation for PROTAC synthesis.
- Facilitates CRBN-mediated target recruitment.
- Available in multiple small pack sizes for synthesis workflows.
Medchemexpress LLC Thalidomide-pyrrolidine hydrochloride | 2616553-35-4 | 98.0% | 335.74 | C15H14ClN3O4 | 5 MG
Thalidomide-pyrrolidine hydrochloride is a cereblon-binding E3 ligase ligand supplied as the hydrochloride salt for use as a building block in PROTAC synthesis and targeted protein degradation research. It is intended for research use and is accompanied by quality documentation.
- Cereblon-binding E3 ligase ligand for PROTAC synthesis.
- Hydrochloride salt form for handling and stability.
- High purity: 98.0%.
- Documented quality: data sheet, certificate of analysis, and safety data sheet available.
- Storage recommendations: store dry at room temperature; in solvent, -80°C (2 years) or -20°C (1 year).
Medchemexpress LLC Thalidomide-5-O-C7-NH2 hydrochloride | 98.1% | 423.89 g/mol | C20H26ClN3O5 | 10 MG
Thalidomide-5-O-C7-NH2 hydrochloride is a thalidomide-derived cereblon ligand supplied as the hydrochloride salt for use in chemical biology and targeted protein degradation research. It is designed to be connected to target ligands via a linker to build PROTACs and other CRBN-recruiting constructs, and includes storage recommendations to preserve compound integrity.
- Facilitates cereblon (CRBN) recruitment for targeted degradation studies.
- Hydrochloride salt form for improved handling and stability.
- Compatible with linker conjugation to form PROTAC molecules.
- Provided with documented molecular and storage data to support experimental planning.
- Suitable for research applications requiring characterized E3 ligase ligands.
Medchemexpress LLC Thalidomide-4-O-C14-NH2 hydrochloride | 99.9% | 522.08 | C27H40ClN3O5 | 10 MG
Thalidomide-4-O-C14-NH2 hydrochloride is a carbon-14 radiolabeled thalidomide derivative used as a cereblon (CRBN) ligand in research applications, including PROTAC assembly. The product is supplied as the hydrochloride salt with high purity and characterized molecular properties for use in biochemical and pharmacokinetic studies.
Medchemexpress LLC IFN-epsilon Human 10ug | 10ug
IFN- protein is a type I interferon that is critical for maintaining baseline levels of IFN-regulated genes (such as 2 -5 -oligoadenylate synthetase IRF7 and ISG15) in the female reproductive tract It acts as a direct mediator providing protection against viral and bacterial genital infections IFN-epsilon Protein Human (His) is the recombinant human-derived IFN-epsilon protein expressed by E coli with N-6 His labeled tag
Medchemexpress LLC Thalidomide-4-F,5-Br | 2740657-28-5 | MFCD34180776 | 99.4% | 355.12 g·mol⁻1 | C13H8BrFN2O4 | 25 MG
Thalidomide-4-F,5-Br is a halogenated thalidomide analogue that functions as an E3 ligase recruiting ligand for targeted protein degradation research. Supplied as a powder in small pre-weighed quantities, it is intended for research use in PROTAC development and studies of ubiquitin-mediated proteolysis.
- Halogenated thalidomide derivative (fluoro and bromo substitutions).
- Acts as a cereblon (CRBN) E3 ligase recruiting ligand for PROTAC applications.
- High purity suitable for research (approximately 99.4%).
- Provided as a powder for easy handling and formulation.
- Available in small pre-weighed quantities for screening and synthesis workflows.
TARGETMOL CHEMICALS INC Thalidomide-O-amido-C4-N3 10MG
Also available in 1 mL, 2 mg, 5 mg, 25 mg, 50 mg and bulk. Please contact Fisher for quotes.Thalidomide-O-amido-C4-N3 (Cereblon Ligand-Linker Conjugates 4) is an E3 ligase ligand-linker conjugate incorporating the Thalidomide-based cereblon ligand and a linker. Purity 97.01%