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Organic heterocyclic compounds that contain a cyclic amide; amide groups consist of a carbonyl carbon atom linked by a single bond to a nitrogen atom and either a hydrogen or a carbon atom. These compounds are the nitrogen analogs of lactones.
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Thalidomide-NH-PEG1-NH2 hydrochloride is a thalidomide-based cereblon ligand-linker conjugate provided as the hydrochloride salt for use in PROTAC development. It features a short PEG linker and a terminal primary amine for conjugation, and is supplied as a lyophilized solid with recommended cold storage for stability.
Potent, cell-permeable PROTAC linker.
Contains a PEG1 linker with a terminal primary amine for conjugation.
Functions as a cereblon ligand for E3 ligase recruitment.
Provided as a lyophilized hydrochloride salt for stability.
High purity (>98%) suitable for research applications.
Store powder at -20 °C; store solutions at -80 °C under inert atmosphere.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More