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Lactims

Organic heterocyclic compounds that consist of a cyclic carboximidic acid characterized by a carbon-nitrogen double bond within the ring; they are tautomeric with the lactams.
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Thermo Scientific Chemicals Cycloheximide, 95%

CAS: 66-81-9 Molecular Formula: C15H23NO4 Molecular Weight (g/mol): 281.35 MDL Number: MFCD00082346 InChI Key: YPHMISFOHDHNIV-QTEFRXOUNA-N Synonym: cycloheximide,actidione,cycloheximide,naramycin a,kaken,actidion,actidone,hizarocin,naramycin,neocycloheximide PubChem CID: 6197 ChEBI: CHEBI:27641 IUPAC Name: 4-[(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]piperidine-2,6-dione SMILES: [H][C@]1(C[C@@H](C)C[C@H](C)C1=O)[C@H](O)CC1CC(=O)NC(=O)C1

EDGE
PubChem CID 6197
CAS 66-81-9
Molecular Weight (g/mol) 281.35
ChEBI CHEBI:27641
MDL Number MFCD00082346
SMILES [H][C@]1(C[C@@H](C)C[C@H](C)C1=O)[C@H](O)CC1CC(=O)NC(=O)C1
Synonym cycloheximide,actidione,cycloheximide,naramycin a,kaken,actidion,actidone,hizarocin,naramycin,neocycloheximide
IUPAC Name 4-[(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]piperidine-2,6-dione
InChI Key YPHMISFOHDHNIV-QTEFRXOUNA-N
Molecular Formula C15H23NO4
2
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(S)-(-)-2-Pyrrolidone-5-carboxylic acid, 98%

CAS: 98-79-3 Molecular Formula: C5H7NO3 Molecular Weight (g/mol): 129.12 MDL Number: MFCD00005272 InChI Key: ODHCTXKNWHHXJC-UHFFFAOYNA-N Synonym: l-pyroglutamic acid,pyroglutamic acid,pidolic acid,5-oxo-l-proline,h-pyr-oh,5-oxoproline,s-5-oxopyrrolidine-2-carboxylic acid,2s-5-oxopyrrolidine-2-carboxylic acid,l-5-oxoproline,l-proline, 5-oxo PubChem CID: 7405 ChEBI: CHEBI:18183 IUPAC Name: (2S)-5-oxopyrrolidine-2-carboxylic acid SMILES: OC(=O)C1CCC(=O)N1

PubChem CID 7405
CAS 98-79-3
Molecular Weight (g/mol) 129.12
ChEBI CHEBI:18183
MDL Number MFCD00005272
SMILES OC(=O)C1CCC(=O)N1
Synonym l-pyroglutamic acid,pyroglutamic acid,pidolic acid,5-oxo-l-proline,h-pyr-oh,5-oxoproline,s-5-oxopyrrolidine-2-carboxylic acid,2s-5-oxopyrrolidine-2-carboxylic acid,l-5-oxoproline,l-proline, 5-oxo
IUPAC Name (2S)-5-oxopyrrolidine-2-carboxylic acid
InChI Key ODHCTXKNWHHXJC-UHFFFAOYNA-N
Molecular Formula C5H7NO3
3
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2-Azetidinone, 98%

CAS: 930-21-2 Molecular Formula: C3H5NO Molecular Weight (g/mol): 71.08 MDL Number: MFCD00013328 InChI Key: MNFORVFSTILPAW-UHFFFAOYSA-N Synonym: 2-azetidinone,beta-propiolactam,azetidinone,propiolactam,azetan-2-one,beta-lactam,2-azetdinone,azetidine-2-one,acmc-209xab PubChem CID: 136721 ChEBI: CHEBI:327119 IUPAC Name: azetidin-2-one SMILES: C1CNC1=O

PubChem CID 136721
CAS 930-21-2
Molecular Weight (g/mol) 71.08
ChEBI CHEBI:327119
MDL Number MFCD00013328
SMILES C1CNC1=O
Synonym 2-azetidinone,beta-propiolactam,azetidinone,propiolactam,azetan-2-one,beta-lactam,2-azetdinone,azetidine-2-one,acmc-209xab
IUPAC Name azetidin-2-one
InChI Key MNFORVFSTILPAW-UHFFFAOYSA-N
Molecular Formula C3H5NO
4
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(S)-(-)-2-Pyrrolidinone-5-carboxylic acid, 98+%

CAS: 98-79-3 Molecular Formula: C5H7NO3 Molecular Weight (g/mol): 129.12 MDL Number: MFCD00005272 InChI Key: ODHCTXKNWHHXJC-UHFFFAOYNA-N Synonym: l-pyroglutamic acid,pyroglutamic acid,pidolic acid,5-oxo-l-proline,h-pyr-oh,5-oxoproline,s-5-oxopyrrolidine-2-carboxylic acid,2s-5-oxopyrrolidine-2-carboxylic acid,l-5-oxoproline,l-proline, 5-oxo PubChem CID: 7405 ChEBI: CHEBI:18183 SMILES: OC(=O)C1CCC(=O)N1

PubChem CID 7405
CAS 98-79-3
Molecular Weight (g/mol) 129.12
ChEBI CHEBI:18183
MDL Number MFCD00005272
SMILES OC(=O)C1CCC(=O)N1
Synonym l-pyroglutamic acid,pyroglutamic acid,pidolic acid,5-oxo-l-proline,h-pyr-oh,5-oxoproline,s-5-oxopyrrolidine-2-carboxylic acid,2s-5-oxopyrrolidine-2-carboxylic acid,l-5-oxoproline,l-proline, 5-oxo
InChI Key ODHCTXKNWHHXJC-UHFFFAOYNA-N
Molecular Formula C5H7NO3
5

DL-Aminoglutethimide, 99%

CAS: 125-84-8 Molecular Formula: C13H16N2O2 Molecular Weight (g/mol): 232.283 MDL Number: MFCD00010122 InChI Key: ROBVIMPUHSLWNV-UHFFFAOYSA-N Synonym: aminoglutethimide,dl-aminoglutethimide,cytadren,orimeten,p-aminoglutethimide,elipten,3-4-aminophenyl-3-ethylpiperidine-2,6-dione,aminoglutetimida,3-4-aminophenyl-3-ethyl-2,6-piperidinedione,aminoglutethimidum PubChem CID: 2145 ChEBI: CHEBI:2654 IUPAC Name: 3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione SMILES: CCC1(CCC(=O)NC1=O)C2=CC=C(C=C2)N

PubChem CID 2145
CAS 125-84-8
Molecular Weight (g/mol) 232.283
ChEBI CHEBI:2654
MDL Number MFCD00010122
SMILES CCC1(CCC(=O)NC1=O)C2=CC=C(C=C2)N
Synonym aminoglutethimide,dl-aminoglutethimide,cytadren,orimeten,p-aminoglutethimide,elipten,3-4-aminophenyl-3-ethylpiperidine-2,6-dione,aminoglutetimida,3-4-aminophenyl-3-ethyl-2,6-piperidinedione,aminoglutethimidum
IUPAC Name 3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione
InChI Key ROBVIMPUHSLWNV-UHFFFAOYSA-N
Molecular Formula C13H16N2O2
6

Medchemexpress LLC Pomalidomide-CO-C5-Br | 2227423-38-1 | 450.28 | 100 MG
SDP

Pomalidomide-CO-C5-Br (Compound 6b) is a conjugated compound of the E3 ligand Pomalidomide and a linker. It can be used to synthesize highly effective PROTAC molecules targeting ADC. It is intended for research use only and not for sale to patients.

  • Conjugated compound of E3 ligand Pomalidomide and linker.
  • Used to synthesize PROTAC molecules.
  • Targets ADCs.
  • For research use only.

ENCOMPASS_PREFERRED
7

Sigma Aldrich 3-Decenoic acid

MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

ENCOMPASS ENCOMPASS_PREFERRED
8

Sigma Aldrich 4-Methoxy-3,5-dimethylbenzenesulfonyl chloride

MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

ENCOMPASS ENCOMPASS_PREFERRED
9

Medchemexpress LLC 2-Pyrimidinamine, 4-[4-(1H-imidazol-1-yl)phenyl]-N-2-propyn-1-yl- | 2234272-10-5 | 98.1% | 25 MG
SDP

AP-C5 is a selective inhibitor of cGMP-dependent protein kinase II (cGKII) with a pIC50 of 7.2. It can be used for research on diarrheal disease and also functions as a click chemistry reagent containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules.

  • Selective inhibitor of cGMP-dependent protein kinase II (cGKII)
  • pIC50 of 7.2 for cGKII
  • Useful for diarrheal disease research
  • Click chemistry reagent with an alkyne group
  • Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc)
  • Potentiates cAMP signaling by PDE inhibition
  • Partially blocks heat-stable toxin (STa)-mediated short-circuit current (Isc) response in mouse ileum

ENCOMPASS_PREFERRED