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Gamma-Mangostin is a novel competitive 5-hydroxytryptamine 2A (5-HT2A) receptor antagonist and a potent epoxidase 2 (COX-2) inhibitor, as well as a transthyroxin protein (TTR) profibrosis inhibitor. It binds to thyroxine (T4)-binding sites and stabilizes the TTR tetramer. This compound exhibits a range of biological activities and is used in the study of metabolic disorders.
Novel competitive 5-HT2A receptor antagonist
Potent COX-2 inhibitor
TTR profibrosis inhibitor
Stabilizes the TTR tetramer
Exhibits anti-inflammatory activity
Exhibits antibacterial activity
Exhibits antioxidant activity
Exhibits anticancer activities
Used in the study of metabolic disorders such as diabetes
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