Oxazinanes
Apexbio Technology LLC Berbamine hydrochloride 6078-17-7 1g
Berbamine hydrochloride (CAS 6078-17-7) is an isoquinoline alkaloid derivative isolated from plants of the Berberidaceae family It exerts its biological effects primarily through modulation of various signaling pathways including inhibition of STAT3 activation and disruption of calcium homeostasis in cells Berbamine hydrochloride has been investigated for its ability to suppress proliferation and induce apoptosis in multiple cancer cell types as well as for its immunomodulatory properties This compound serves as a valuable tool for studies exploring mechanisms of tumorigenesis and evaluating potential therapeutic strategies in cancer and immune-related research
Cayman Chemical PIK75 hydrochloride
A selective inhibitor of p110α with an IC50 value of 5.8 nM; inhibits p110γ and p110β with IC50 values of 0.076 µM and 1.3 µM, respectively
eMolecules 78335-26-9 | 4-(Morpholin-4-yl)-2-(trifluoromethyl)aniline | Combi-Blocks, Inc. | MFCD01436021 | 246.233 | C11H13F3N2O | 96.000 | Nc1ccc(cc1C(F)(F)F)N1CCOCC1 | 1g | 603132120
4-(Morpholin-4-yl)-2-(trifluoromethyl)aniline | Combi-Blocks, Inc. | 78335-26-9 | MFCD01436021 | 246.233 | C11H13F3N2O | 96.000 | Nc1ccc(cc1C(F)(F)F)N1CCOCC1 | 1g | 603132120
Cayman Chemical Fingolimod hydrochloride
An immune modulator and a prodrug form of FTY720 phosphate; decreases the number of circulating lymphocytes in mice at 1 mg/kg; increases skin allograft survival in rats from 0.3-3 mg/kg; prevents disease development in a rat model of EAE; inhibits S1P lyase from 0.3-30 µM
Chemscene ChemScene | Methyl 3-oxo-3,4-dihydro-2H-1,4-benzoxazine-7- carboxylate | 1G | CS-W000707 | 0.98 | 142166-00-5| MFCD07774184 | 207.19
ChemScene | Methyl 3-oxo-3,4-dihydro-2H-1,4-benzoxazine-7- carboxylate | 1G | CS-W000707 | 0.98 | 142166-00-5| MFCD07774184 | 207.19
Selleck Chemical LLC Itopride hydrochloride S4619-100mg
Itopride hydrochloride (Ganaton HSR803) is an AChE inhibitor The IC50 of itopride with AChE is 2 04 /- 0 27 M
eMolecules 109-11-5 | Morpholin-3-one | Synthonix | MFCD00631009 | 101.105 | C4H7NO2 | 97.000 | O=C1COCCN1 | 100g | 649430339
Morpholin-3-one | Synthonix | 109-11-5 | MFCD00631009 | 101.105 | C4H7NO2 | 97.000 | O=C1COCCN1 | 100g | 649430339
Selleck Chemical LLC MPTP hydrochloride S4732-200mg
MPTP hydrochloride is a dopaminergic neurotoxin and cause selective destruction of dopaminergic neurons in animal models of parkinsonism MPTP hydrochloride induces apoptosis MPTP hydrochloride can be used to induce animal models of Parkinson s disease
Cayman Chemical DLthreoPDMP hydrochloride
An inhibitor of sphingolipid biosynthesis; inhibits glucosylceramide synthase by 33 and 48% in MDCK cell homogenates at 5 and 10 µM; reduces the synthesis of glucosylceramide increases cellular ceramide, and induces cell cycle arrest; increases Aβ42 and Aβ39 production independent of ceramide metabolism via modulation of γ-secretase activity
Cayman Chemical SRT 1720 hydrochloride
A selective small molecule activator of SIRT1 that is 1,000-fold more potent than resveratrol; improves insulin sensitivity, lowers plasma, glucose and increases mitochondrial capacity in diet-induced obese and diabetic leptin-deficient ob/ob mice after one week of treatment with an oral dose of 100 mg/kg once daily.
Cayman Chemical H89 hydrochloride
A potent, non-selective inhibitor of PKA with an IC50 value of 0.14 µM (Ki = 48 nM) that is widely used to disrupt PKA signaling; inhibits S6K1, MSK1, ROCK2, PKBa, and MAPKAP-K1b with IC50 values of 0.08, 0.12, 0.27, 2.6, and 2.8 µM, respectively