Oxazinanes
TARGETMOL CHEMICALS INC K145 HYDROCHLORIDE 50MG
Also available in 5 mg 10 mg 25 mg and bulk. Please contact Fisher for quotes. K145 hydrochloride is a selective sphk2 inhibitor with substrate competitiveness and oral activity with IC50 of 4.3 µM and Ki of 6.4 µM. K145 hydrochloride can induce apoptosis and has strong antitumor activity. purity: 99%
eMolecules Combi-Blocks Inc 4-Methoxytetrahydro-2h-pyran-4-carboxylic acid 250mg 818529805 JC-0171 98 000 1010836-49-3 MFCD12024537 160 169 C7H12O4
Combi-Blocks Inc 4-Methoxytetrahydro-2h-pyran-4-carboxylic acid 250mg 818529805 JC-0171 98 000 1010836-49-3 MFCD12024537 160 169 C7H12O4
Cayman Chemical Methedrone hydrochloride
A phenethylamine, amphetamine, and cathinone derivative that acts as a triple reuptake/release/reversible MAO inhibitor; intended for use as a standard for the forensic analysis of samples that may contain this compound
Cayman Chemical PropenylLNIO hydrochloride
A potent, selective iNOS inhibitor (Kis = 17, 10.3 and 58.2 µM for iNOS, nNOS, and eNOS, respectively, for initial rate binding kinetics); demonstrates reversible tight binding inhibition that is selective for iNOS over nNOS (Kis = 0.56 and 6 µM, respectively)
eMolecules METHYL 2-AMINO-4-(MORPHOLINE-4-CARBONYL)BENZOATE | 322764-64-7 | MFCD11501885 | 1g
AstaTech | METHYL 2-AMINO-4-(MORPHOLINE-4-CARBONYL)BENZOATE | 1g | 112531767 | AR2624 | 95.000 | 322764-64-7 | MFCD11501885 | 264.281 | C13H16N2O4
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eMolecules Building Block Tool
Medchemexpress LLC 11β-HSD1-IN-8 | 386704-15-0 | MFCD01862654 | 95.0% | 247.17 | C10H8F3NO3 | 250 MG
11β-HSD1-IN-8 is a small-molecule inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) with a reported IC50 of 2.3 μM for the human enzyme. Supplied as a high-purity solid research reagent, it is intended for in vitro studies of metabolic and cognitive disorders such as diabetes and cognitive decline.
- Selective inhibition of 11β-HSD1 (IC50 2.3 μM).
- Intended for in vitro research of metabolic and cognitive disorders.
- High stated purity of 95.0%.
- Solid form; off-white to light yellow appearance.
- Storage: powder stable at -20°C (3 years) or 4°C (2 years).
- Molecular formula C10H8F3NO3; molecular weight 247.17.
eMolecules Pharmablock N-ethylpropan-2-amine 25g 713093358 PBT6054 19961-27-4 MFCD00015105 87.166 C5H13N
Pharmablock N-ethylpropan-2-amine 25g 713093358 PBT6054 19961-27-4 MFCD00015105 87.166 C5H13N
TARGETMOL CHEMICALS INC SKF-96365 HYDROCHLORIDE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SKF-96365 hydrochloride (SKF96365) a SOCE inhibitor exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal Y cells. SKF-96365 hydrochloride can induce cytoprotective autophagy to delay apoptosis by preventing the release of cytochrome c (cyt c) from the mitochondria into the cytoplasm. Mechanistically SKF-96365 hydrochloride treatment inhibited the calcium/calmodulin-dependent protein kinase II(gamma) (CaMKII(gamma))/AKT signaling cascade in vitro and in vivo. Overexpression of CaMKII(gamma) or AKT abolished the effects of SKF-96365 on Y cells suggesting a critical role of the CaMKII(gamma)/AKT signaling pathway in SFK-96365-induced biological effects. SKF-96365 hydrochloride inhibited hERG current in a concentration-dependent manner. purity: 99%
TARGETMOL CHEMICALS INC LURASIDONE HYDROCHLORIDE 100MG
Also available in 5 mg 10 mg 25 mg 50 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Lurasidone hydrochloride (Lurasidone HCl) is a thiazole derivative and atypical antipsychotic agent that functions as a dopamine D2 receptor antagonist; serotonin 5-HT2 receptor antagonist serotonin 5-HT7 receptor antagonist an antagonist of the adrenergic (alpha)2A and (alpha)2C receptors as well as a partial serotonin 5-HT1A receptor agonist. It is used in the treatment of schizophrenia and bipolar disorder. purity: 99%
TARGETMOL CHEMICALS INC DONITRIPTAN HYDROCHLORID 25MG
Also available in 1 mg 2 mg 5 mg 10 mg 50 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Donitriptan hydrochloride (Donitriptan monohydrochloride) is a potent high efficacy agonist of 5-HT1B/1D receptors with pKis of 9.4 and 9.3 respectivelypurity: 99%