Oxazinanes

Organic heterocyclic compounds that consist of a six-membered ring that has four carbon atoms, one nitrogen atom, and one oxygen atom.

Search Within Results

436 – 450 of 2,960 results

436

Apexbio Technology LLC TRIMETAZIDINE-HYDROCHLORIDE

Trimetazidine (hydrochloride) (CAS No 13171-25-0) is a pharmacological agent primarily studied in the cardiovascular research field Originating from anti-ischemic drug development it functions by optimizing cellular metabolism under hypoxic conditions predominantly through the inhibition of long-chain 3-ketoacyl-CoA thiolase in the cardiac mitochondrial beta-oxidation pathway This action shifts fatty acid oxidation to glucose oxidation enhancing myocardial glucose consumption and efficiency during ischemic episodes Common in vitro activity occurs in the nanomolar to low micromolar range Trimetazidine is frequently used in various experimental applications including cell models like cardiomyocytes animal studies investigating myocardial protection and drug screening for cardiovascular therapies Experimental concentrations typically depend on the specific research design enabling a tailored approach to exploring its cardioprotective effects in different contexts

Pricing & Availability

437

Apexbio Technology LLC CLINAFLOXACIN-HYDROCHLORIDE

Clinafloxacin (hydrochloride) (CAS No 105956-99-8) is an investigational antibacterial agent belonging to the fluoroquinolone class known for its broad-spectrum activity Originating from chemical modifications to enhance antibacterial efficacy it targets bacterial DNA gyrase and topoisomerase IV crucial enzymes for DNA replication and transcription Clinafloxacin exhibits potent antibacterial activity in the nanomolar to low micromolar range against various gram-positive and gram-negative bacteria It is frequently used in cell models and animal studies to evaluate antibacterial efficacy and resistance mechanisms Additionally it is utilized in drug screening assays to explore new therapeutic options for bacterial infections Experimental concentrations typically depend on the specific research design allowing flexibility in applications across different models and conditions

Pricing & Availability

438

Medchemexpress LLC 8-Azaadenine | 1123-54-2 | 99.9% | 136.12 | 250 MG

8-Azaadenine is an inhibitor of Xanthine Oxidase with an IC50 of 0.54 μM and a Ki of 0.66 μM. It is produced via the metabolism of 8-Azaadenosine and can be incorporated into polynucleotide chains alongside 8-Azaguanine to impact purine metabolism. This product is used in cancer studies and can also be synthesized into various derivatives through alkylation reactions, which demonstrate antiviral activity.

Inhibits Xanthine Oxidase with an IC50 of 0.54 μM and a Kᵢ of 0.66 μM
Produced via the metabolism of 8-Azaadenosine
Incorporated into polynucleotide chains to affect purine metabolism
Used in the study of cancer
Can be synthesized into derivatives with antiviral activity

Pricing & Availability

439

Chemscene CHEMSCENE

5000575423 1-4-ETHOXYPHENYL ETHANONE 100G

Pricing & Availability

440

Apexbio Technology LLC Trigonelline-Hydrochloride

Trigonelline Hydrochloride (CAS No 6138-41-6) is a compound commonly studied in the field of biomedical research due to its potential therapeutic benefits and origins in plants such as fenugreek It operates through mechanisms involving modulation of glucose metabolism and the inhibition of protein glycation impacting pathways related to diabetes and neurodegenerative diseases In vitro activity assessments frequently indicate efficacy in the nanomolar to low micromolar range showcasing its potential as a bioactive agent Typical applications include its use in various cell models to study cellular metabolism as well as in animal studies for evaluating potential treatments for metabolic disorders It is also employed in drug screening panels to identify compounds that could mitigate oxidative stress Experimental concentrations typically depend on the specific research design reflecting its diverse applicability and the ongoing exploration of its pharmacological properties