Oxazinanes
Medchemexpress LLC Quisinostat dihydrochloride (Jnj-26481585 dihydrochloride) | 875320-31-3 | C21H28Cl2N6O2 | 100 MG
Quisinostat dihydrochloride is a potent, orally active pan-HDAC (histone deacetylase) inhibitor. It has shown a broad spectrum of antitumoral activity and can induce autophagy in neuroblastoma cells. The product appears as a solid, with a color ranging from white to yellow.
- Potent pan-HDAC inhibitor
- Broad spectrum antitumoral activity
- Induces autophagy
- High purity (99.05%)
- Intended for research use only
Medchemexpress LLC 7-dimethylaminocoumarin-4-acetic acid | 80883-54-1 | MFCD00857826 | 98.1% | 247.25 g/mol | C13H13NO4 | 250 MG
7-Dimethylaminocoumarin-4-acetic acid is a coumarin-based fluorescent probe used in fluorescence assays, labeling, and assay development. It is supplied as a solid reagent with documented purity, solubility, and storage guidance suitable for in vitro and formulation studies.
- Fluorescent probe with coumarin core.
- Purity 98.05%.
- Molecular weight 247.25 g/mol.
- Molecular formula C13H13NO4.
- CAS number 80883-54-1.
- Recommended solvent: DMSO (100 mg/mL); requires ultrasonic treatment; use newly opened DMSO.
- Storage: 4°C, protect from light; in solution: -80°C (6 months), -20°C (1 month).
- Suitable for small-scale fluorescence and labeling experiments.
TARGETMOL CHEMICALS INC DELAPRIL HYDROCHLORIDE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Delapril hydrochloride (indalapril) is a prodrug; it is converted into two active metabolites 5-hydroxy delapril diacid and delapril diacid. These metabolites bind completely to and inhibit angiotensin-converting enzyme (ACE) hence blocking angiotensin I to angiotensin II conversion. purity: 99%
TARGETMOL CHEMICALS INC HLCL-61 HYDROCHLORIDE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. HLCL-61 hydrochloride (HLCL-61 HCL) is a potent and selective PRMT5 inhibitor for the treatment of acute myeloid leukemia. purity: 99%
Apexbio Technology LLC Amsacrine hydrochloride 54301-15-4 10mM (in 1mL DMSO)
Amsacrine hydrochloride (CAS 54301-15-4) also known as m-AMSA is a small molecule inhibitor of DNA topoisomerase II By interfering with the religation step of the topoisomerase II catalytic cycle it induces DNA strand breaks and disrupts DNA replication and transcription In vitro studies have shown that Amsacrine hydrochloride exhibits cytotoxicity against various cancer cell lines including bladder (HT1376 RT112 RT4) and testicular (833K Susa GH) cancer cells with IC50 values ranging from 5 0 to 190 2 ng/ml Testicular cancer cell lines display greater sensitivity to this agent compared to bladder cancer cell lines Amsacrine hydrochloride is utilized in research exploring DNA damage mechanisms and antineoplastic drug responses
Medchemexpress LLC CN128 hydrochloride | 1335282-05-7 | 98.2% | 10 MM 1 ML
CN128 hydrochloride is an orally active and selective iron chelator. It is used for the research of β-thalassemia.
- Orally active and selective iron chelator
- High selectivity for iron(III) over other metals
- Lacks genetic toxicity and is well-tolerated
- Exhibits good oral bioavailability
- Demonstrates good iron scavenging efficacy in rats
- Iron removal efficacies are dose-dependent
eMolecules 141-86-6 | 2,6-Diaminopyridine | Ambeed | MFCD00006329 | 109.132 | C5H7N3 | 98.000 | Nc1cccc(N)n1 | 5g | 490566444
2,6-Diaminopyridine | Ambeed | 141-86-6 | MFCD00006329 | 109.132 | C5H7N3 | 98.000 | Nc1cccc(N)n1 | 5g | 490566444
Selleck Chemical LLC Celiprolol hydrochloride
Celiprolol is a 1-adrenoceptor antagonist with partial 2 agonist activity
Selleck Chemical LLC Atipamezole hydrochloride S4649-50mg
Atipamezole (Antisedan MPV1248) is a synthetic 2 adrenergic receptor antagonist It has also been researched in humans as a potential anti-Parkinsonian drug Atipamezole hydrochloride is hydrochloride form of atipamezole
Selleck Chemical LLC Irinotecan hydrochloride S5026-25mg
Irinotecan (CPT-11 ( )-Irinotecan) hydrochloride is an inhibitor of Topoisomerase I (Topo I) that exhibits cytotoxicity in LoVo cells and HT-29 cells with IC50 of 15 8 M and 5 17 M respectively
Selleck Chemical LLC Levomilnacipran Hydrochloride
Levomilnacipran Hydrochloride is a selective serotonin and norepinephrine reuptake inhibitor with antidepressant activity
Apexbio Technology LLC THIP hydrochloride 85118-33-8 10mM (in 1mL DMSO)
THIP hydrochloride (CAS 85118-33-8) is a small-molecule agonist of GABA receptors with primary activity in the central nervous system It selectively binds to GABAA receptor subtypes displaying affinity for 1 2 2 5 and 4 3 subunits In pharmacological studies THIP hydrochloride demonstrates subunit-specific efficacy with ED50 values of 143 M for 1 2 2 28 129 M for 5 and 6 M for 4 3 This compound is widely employed as a research tool in neuroscience to investigate GABAergic neurotransmission receptor pharmacology and explore potential therapeutic strategies related to neural modulation
TARGETMOL CHEMICALS INC ALE-0540 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. ALE-0540 is a nonpeptidic heterocyclic molecule that inhibits the binding of NGF to p75 and TrkA as well as signal transduction and biological responses mediated by TrkA receptors. purity: 97%
Medchemexpress LLC Sapropterin dihydrochloride | 69056-38-8 | 99.8% | C9H17Cl2N5O3 | 50 MG
Sapropterin ((6R)-BH4; (6R)-Tetrahydro-L-biopterin) dihydrochloride is an orally active phenylalanine hydroxylase (PAH) cofactor. It is effective in reducing blood phenylalanine concentrations and can be used in the study of phenylketonuria (PKU). Additionally, Sapropterin dihydrochloride can aggravate experimental autoimmune encephalomyelitis (EAE).
- Orally active phenylalanine hydroxylase (PAH) cofactor.
- Effective in reducing blood phenylalanine concentrations.
- Used in the study of phenylketonuria (PKU).
- Can aggravate experimental autoimmune encephalomyelitis (EAE).
Medchemexpress LLC Decloxizine dihydrochloride | 13073-96-6 | 99.7% | C21H30Cl2N2O2 | 500 MG
Decloxizine dihydrochloride acts as a histamine 1 receptor antagonist and is intended for research use only. This compound presents as a white to off-white solid with a high purity of 99.69%.
- Antagonizes histamine 1 receptors
- Solid form
- High purity of 99.69%
- Suitable for various research applications
- Recommended storage at 4°C in sealed conditions, away from moisture
- Solutions can be stored at -80°C for up to 6 months or -20°C for 1 month