Oxazinanes
![Aobchem [3-(Pyridin-3-yl)phenyl]boronic acid | ≥95% | CAS 351422-72-5 | C11H10BNO2 | 10g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5001090524.png-250.jpg)
Aobchem [3-(Pyridin-3-yl)phenyl]boronic acid | ≥95% | CAS 351422-72-5 | C11H10BNO2 | 10g
[3-(Pyridin-3-yl)phenyl]boronic acid | ≥95% | CAS 351422-72-5 | C11H10BNO2 | 10g
Cayman Chemical PIK-75, Purity: ≥98%, CAS: 372196-67-3, 5 mg
A selective inhibitor of p110α with an IC50 value of 5.8 nM; inhibits p110γ and p110β with IC50 values of 0.076 µM and 1.3 µM, respectively
Aobchem (8-Bromonaphthalen-1-yl)boronic acid | ≥97% | CAS 167105-03-5 | C10H8BBrO2 | 5g
(8-Bromonaphthalen-1-yl)boronic acid | ≥97% | CAS 167105-03-5 | C10H8BBrO2 | 5g
![Aobchem 7-Bromo-3 4-dihydro-2H-benzo[b][1 4]dioxepine | ≥97% | CAS 147644-11-9 | C9H9BrO2 | 5g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5001094057.png-250.jpg)
Aobchem 7-Bromo-3 4-dihydro-2H-benzo[b][1 4]dioxepine | ≥97% | CAS 147644-11-9 | C9H9BrO2 | 5g
7-Bromo-3 4-dihydro-2H-benzo[b][1 4]dioxepine | ≥97% | CAS 147644-11-9 | C9H9BrO2 | 5g
Aobchem (3-Chloro-4-cyanophenyl)boronic acid | ≥95% | CAS 1008415-02-8 | C7H5BClNO2 | 1g
(3-Chloro-4-cyanophenyl)boronic acid | ≥95% | CAS 1008415-02-8 | C7H5BClNO2 | 1g
Aobchem 2 3-Dimethoxypyridine-5-boronic acid | ≥95% | CAS 1346526-61-1 | C7H10BNO4 | 5g
2 3-Dimethoxypyridine-5-boronic acid | ≥95% | CAS 1346526-61-1 | C7H10BNO4 | 5g
Aobchem (8-Bromonaphthalen-1-yl)boronic acid | ≥97% | CAS 167105-03-5 | C10H8BBrO2 | 10g
(8-Bromonaphthalen-1-yl)boronic acid | ≥97% | CAS 167105-03-5 | C10H8BBrO2 | 10g
Cayman Chemical DL-threo-PDMP (hydrochloride), Purity: ≥98%, CAS: 80938-69-8, 10 mg
An inhibitor of sphingolipid biosynthesis; inhibits glucosylceramide synthase by 33 and 48% in MDCK cell homogenates at 5 and 10 µM; reduces the synthesis of glucosylceramide increases cellular ceramide, and induces cell cycle arrest; increases Aβ42 and Aβ39 production independent of ceramide metabolism via modulation of γ-secretase activity
Cayman Chemical FR122047 (hydrochloride), Purity: ≥98%, CAS: 130717-51-0, 5 mg
A selective COX-1 inhibitor (IC50 = 0.028 µM for the human enzyme); selective for COX-1 over COX-2 (IC50 = 65 µM); inhibits arachidonic acid, collagen, and ADP-induced platelet aggregation in human platelet-rich plasma (IC50 = 180-200 nM); unlike aspirin, it does not induce gastric damage at 100 mg/kg, p.o.; has an anti-inflammatory effect in a rat models of collagen-induced arthritis
Cayman Chemical PIK-75, Purity: ≥98%, CAS: 372196-67-3, 1 mg
A selective inhibitor of p110α with an IC50 value of 5.8 nM; inhibits p110γ and p110β with IC50 values of 0.076 µM and 1.3 µM, respectively
Cayman Chemical SB-242084 (hydrochloride), Purity: ≥98%, CAS: 1049747-87-6, 1 mg
An antagonist of the 5-HT2C receptor (pKi = 9.0), with at least 100-fold more selectivity over other 5-HT, dopamine, or adrenergic receptors; brain penetrant with significant anxiolytic activity; used extensively in animal research
AdipoGen 5-DTAF hydrochloride
Chemical. CAS 21811-74-5. Formula C23H12Cl2N4O5 . HCl. MW 495.3 . 36.5. Synthetic. 5-DTAF is highly reactive with proteins. Unlike other reactive fluoresceins, 5-DTAF not only reacts with amino groups, but also reacts with thiol groups and even directly reacts with hydroxy groups such as polysaccharides and other alcohols in aqueous solution at pH above 9. Due to its high reactivity, 5-DTAF is also used to label carbohydrates. Spectral properties Abs/Em = 492/517 nm
Cayman Chemical SRT 1720 (hydrochloride), Purity: ≥98%, CAS: 1001645-58-4, 5 mg
A SIRT1 activator (EC1.5 = 0.16 µM in a cell-free fluorescence polarization assay); reduces acetylated p53 levels in U2OS cells at 0.1 µM; reduces fed blood glucose levels, improves insulin sensitivity, and increases mitochondrial capacity in a DIO mouse model of diabetes at 100 mg/kg; improves liver, adipose tissue, and skeletal muscle insulin sensitivity in Zucker fa/fa rats; decreases synovitis and delays osteoarthritis progression in mice at 25 mg/kg