Oxazinanes
TARGETMOL CHEMICALS INC AZEPEXOLE HYDROCHLORIDE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Azepexole hydrochloride (4H-Oxazolo[45-d]azepin-2-amine 6-ethyl-5678-tetrahydro- hydrochloride (11)) is a potent (alpha)2-Adrenoceptor agonist with anaesthetic effects. purity: 99%
Medchemexpress LLC 7,8-Dihydro-L-biopterin | 6779-87-9 | 99.79% | 239.23 | 100 MG
7,8-Dihydro-L-biopterin is a NOS uncoupling inducer that can cross the blood-brain barrier. It is a reduced non-conjugated pteridine and the main metabolite of 4-amino-tetrahydro-L-biopterin, which undergoes photooxidation to form biopterin. This compound promotes the conversion of nitric oxide synthase to a superoxide-producing form, leading to increased oxidative stress in the renal outer medulla and inducing apoptosis.
- NOS uncoupling inducer
- Can cross the blood-brain barrier
- Promotes conversion of nitric oxide synthase to a superoxide-producing form
- Increases oxidative stress in the renal outer medulla
- Induces apoptosis
- Sensitive to inhibitory effect of SOD
- Used in research related to salt-sensitive hypertension and neurodegenerative diseases
eMolecules Ambeed (R)-3-Methoxypyrrolidine 5g 589946567 A848949 120099-60-7 MFCD09953439 101.149 C5H11NO
Ambeed (R)-3-Methoxypyrrolidine 5g 589946567 A848949 120099-60-7 MFCD09953439 101.149 C5H11NO
eMolecules ChemScene 25-Dibromopyridin-3-amine 25g 572179909 CS-0052143 90902-84-4 MFCD09266224 251.909 C5H4Br2N2
ChemScene 25-Dibromopyridin-3-amine 25g 572179909 CS-0052143 90902-84-4 MFCD09266224 251.909 C5H4Br2N2
Selleck Chemical LLC Bobcat339 hydrochloride
Bobcat339 is a selective cytosine-based TET enzyme inhibitor with IC50 of 33 M and 73 M for TET1 and TET2 respectively Bobcat339 can reduce DNA 5-hydroxymethylcytosine abundance by inhibiting TET enzyme function in living cells and provide support for its utility as a viable pharmacological probe
Selleck Chemical LLC Nilotinib hydrochloride S5205-10mM/1mL
Nilotinib hydrochloride (AMN-107) is the hydrochloride salt form of nilotinib an orally bioavailable Bcr-Abl tyrosine kinase inhibitor with antineoplastic activity
eMolecules AstaTech BUT-3-YNE-1-SULFONYL CHLORIDE 1g 716226761 E84699 95.000 936644-39-2 MFCD19598006 152.590 C4H5ClO2S
AstaTech BUT-3-YNE-1-SULFONYL CHLORIDE 1g 716226761 E84699 95.000 936644-39-2 MFCD19598006 152.590 C4H5ClO2S
Medchemexpress LLC Mirodenafil dihydrochloride | 862189-96-6 | 99.1% | 604.59 | 100 MG
Mirodenafil dihydrochloride is an orally active, potent, reversible, and selective phosphodiesterase 5 (PDE5) inhibitor. It also acts as a glucocorticoid receptor (GR) modulator and activates the Wnt/β-catenin signaling pathway. This compound is used in research for erectile dysfunction (ED), Alzheimer's disease (AD), and systemic sclerosis (SSc).
- Exerts neuroprotective functions by activating the cGMP/PKG/CREB signaling pathway.
- Enhances neuronal survival by protecting mitochondrial membrane potential and inhibiting apoptosis.
- Inhibits GSK-3β signaling, reducing tau phosphorylation and amyloid beta production.
- Inhibits transcriptional activity and homodimerization of the glucocorticoid receptor (GR).
- Ameliorates dermal fibrosis in an SSc mouse model by inhibiting the TGF-β signaling pathway.
- Improves cognitive-behavioral performance in transgenic AD mice.
Medchemexpress LLC N1,N1-dimethylpropane-1,2-diamine | 108-15-6 | MFCD00014812 | 99.3% | 102.18 | 500 MG
N1,N1-dimethylpropane-1,2-diamine is a laboratory chemical used in the manufacture of substances. It is intended for research use only and should be handled by experienced personnel. The product has not been fully validated for medical applications and is stable under recommended storage conditions.
- Laboratory chemicals
- Manufacture of substances
- Research use only
- Stable under recommended storage conditions
- Appearance: liquid, colorless to light yellow
Medchemexpress LLC Vacquinol-1 dihydrochloride (NSC13316 dihydrochloride) | 2309312-85-2 | 99.7% | 425.78 | 100 MG
Vacquinol-1 (NSC13316) dihydrochloride is a MKK4-specific activator that activates MAPK pathways. It specifically induces human glioblastoma cell (GC) death, attenuates tumor progression, and prolongs survival in a glioblastoma multiforme (GBM) mouse model. Vacquinol-1 dihydrochloride also induces apoptosis in hepatocellular carcinoma (HCC) cells.
- Activates MAPK pathways
- Induces human glioblastoma cell death
- Attenuates tumor progression
- Prolongs survival in a glioblastoma multiforme mouse model
- Induces apoptosis in hepatocellular carcinoma cells
Medchemexpress LLC 7,8-Dihydro-L-biopterin | 6779-87-9 | 99.8% | 239.23 | 1 ML
7,8-Dihydro-L-biopterin | 6779-87-9 | 99.8% | 239.23 | 1 ML
Selleck Chemical LLC Dibenamine Hydrochloride S5432-25mg
Dibenamine (N-(2-Chloroethyl)dibenzylamine Sympatholytin Dibenzylchlorethamine) is an irreversible blocker of 1 adrenoceptors
Medchemexpress LLC N1,N1-Dimethylpropane-1,2-diamine dihydrochloride | 75975-34-7 | 96.0% | 175.10 | 500 MG
N1,N1-Dimethylpropane-1,2-diamine dihydrochloride is a drug intermediate for the synthesis of various active compounds.