Oxazinanes
Medchemexpress LLC 1(2H)-Isoquinolinone | 491-30-5 | 145.16 | 25 G
1-Hydroxyisoquinoline is a biochemical reagent suitable for life science related research. It can be utilized as a biological material or an organic compound. This product is for research use only and not intended for patient use.
- Can inhibit DNA repair Poly (ADP-ribose) polymerase 1
- Inhibits in permeabilized L1210 murine leukemia cells with an IC50 of 15.8 μM
- Suitable for various life science related research applications
TARGETMOL CHEMICALS INC CSRM617 HYDROCHLORIDE 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CSRM617 hydrochloride is a selective small-molecule inhibitor of the transcription factor ONECUT2 ( OC2 a master regulator of androgen receptor) with a K d of 7.43 uM in SPR assays directly binds to OC2-HOX domain. CSRM617 hydrochloride induces apoptosis through the appearance of cleaved Caspase-3 and PARP. CSRM617 hydrochloride is well tolerated in the mouse model of prostate cancer [1]purity: 99%
Medchemexpress LLC Mmpip hydrochloride | 1215566-78-1 | 99.1% | 369.80 g/mol | C19H16ClN3O3 | 1 ML
MMPIP hydrochloride is an allosteric metabotropic glutamate receptor 7 (mGluR7) selective antagonist supplied as a ready-to-use 10 mM solution in dimethyl sulfoxide (DMSO). It is intended for in vitro pharmacology and receptor modulation studies and is provided with high purity and characterized identity.
- Allosteric mGluR7 antagonist for receptor modulation studies.
- Provided as a 10 mM solution in DMSO for immediate use.
- High purity suitable for pharmacological assays.
- Available in multiple solid and solution pack sizes for flexibility.
- Characterized by CAS 1215566-78-1 and confirmed molecular weight of 369.80 g/mol.
TARGETMOL CHEMICALS INC K34C HYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. K34c hydrochloride is an alpha5(beta)1 integrin antagonist for glioblastoma study.
Selleck Chemical LLC Ribociclib hydrochloride S5187-25mg
Ribociclib (LEE011) hydrochloride is a highly specific dual inhibitor of CDK4 and CDK6 with IC50 of 10 nM and 39 nM respectively
Medchemexpress LLC Decloxizine dihydrochloride | 13073-96-6 | 99.69% | C21H30Cl2N2O2 | 25 MG
Decloxizine dihydrochloride is a histamine 1 receptor antagonist.
- H1 receptor antagonist
- Suitable for neurological research
- Applicable in studies of eye or ear disease
- Relevant for metabolic or endocrine disease research
- Used in inflammation or immune system disease studies
- Involved in neurodegenerative disease research
- Related to lipid metabolism
- Applicable to Parkinson's disease research
- Relevant for obesity studies
- Used in endocrinology research
Medchemexpress LLC Bay 61-3606 dihydrochloride | 648903-57-5 | MFCD08276916 | 99.5% | 463.32 g·mol^-1 | C20H20Cl2N6O3 | 10 MG
BAY 61-3606 dihydrochloride is a potent, ATP-competitive, reversible, and highly selective inhibitor of spleen tyrosine kinase (Syk), provided as the dihydrochloride salt for research use. It is intended for biochemical and cell-based studies of kinase signaling and apoptosis, and has reported biochemical potency (Ki = 7.5 nM; IC50 ≈ 10 nM) and high purity for reliable experimental results.
- High biochemical potency (Ki = 7.5 nM; IC50 ≈ 10 nM).
- High reported purity (≈99.5%).
- Provided as dihydrochloride salt suitable for cell-based assays.
- Characterized by COA, HNMR, and LC-MS documentation.
- Useful for studying Syk-dependent signaling and apoptosis.
TARGETMOL CHEMICALS INC ML-7 HYDROCHLORIDE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. ML-7 hydrochloride (ML-7 HCl) is a cell-permeable reversible effective ATP-competitive and specific inhibitor of myosin light chain kinase (Ki 300 nM); also inhibits smooth-muscle myosin light chain kinase PKA and PKC. purity: 99%
TARGETMOL CHEMICALS INC LP-922761 5MG
Also available in 1 mg and bulk. Please contact Fisher for quotes. LP-922761 is a potent selective and orally active AAK1 inhibitor with inhibitory effects on BMP-2 induced protein kinase (BIKE). purity: 97%
TARGETMOL CHEMICALS INC BLARCAMESINE HYDROCHLORI 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Blarcamesine hydrochloride (AVex-73 hydrochloride) is a Sigma-1 Receptor agonist (IC50 860 nM). purity: 99%
Selleck Chemical LLC Gatifloxacin hydrochloride
Gatifloxacin (AM-1155 CG5501 BMS-206584 PD135432) hydrochloride is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity Gatifloxacin hydrochloride inhibits bacterial type II topoisomerases with IC50 of 13 8 g/ml and 0 109 g/ml for S aureus topoisomerase IV and E coli DNA gyrase respectively
Selleck Chemical LLC ICCB-19 hydrochloride
ICCB-19 hydrochloride is an inhibitor of TNFRSF1A Associated Via Death Domain (TRADD) with IC50 of 1 12 M and 2 01 M for protecting Velcade-induced apoptosis in Jurkat cells and protecting RDA in MEFs respectively ICCB-19 indirectly inhibits Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) ICCB-19 effectively induces autophagy
![Medchemexpress LLC 1-methyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one | 5334-56-5 | MFCD01312343 | 150.14 g/mol | C6H6N4O | 5 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000209958.png-250.jpg)
Medchemexpress LLC 1-methyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one | 5334-56-5 | MFCD01312343 | 150.14 g/mol | C6H6N4O | 5 G
1-methyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS 5334-56-5) is a pyrazolopyrimidinone small-molecule used as a biochemical reagent and reference compound in life-science research.
- Chemical formula C6H6N4O, molecular weight 150.14 g/mol.
- Solid form with a reported melting point >250 °C.
- Commonly used as a biochemical reagent and reference compound in pharmacological and biochemical studies.
- Typical supplier package sizes include small gram quantities for research use.
- Reported purities vary by supplier; verify the exact purity from the product-specific safety data sheet or manufacturer listing.
Medchemexpress LLC RF9 hydrochloride | 00-00-0 | 99.9% | 519.08 | C26H39ClN6O3 | 1 ML
RF9 hydrochloride is a potent and selective antagonist of Neuropeptide FF (NPFF) receptors, with reported Ki values of 58 nM for hNPFF1R and 75 nM for hNPFF2R. It is supplied for research use as high-purity material, available as a 10 mM solution in DMSO or as dry powder in multiple vial sizes.
- Potent NPFF receptor antagonist (Ki = 58 nM for hNPFF1R; Ki = 75 nM for hNPFF2R).
- Molecular formula C26H39ClN6O3.
- Molecular weight 519.08.
- Purity >99.9%.
- Available as 10 mM solution in DMSO and as dry powders in multiple vial sizes.
- Intended for in vitro pharmacology and receptor binding studies.
TARGETMOL CHEMICALS INC Milnacipran hydrochloride
Also available in 10 mg, 25 mg, 50 mg, 200 mg, 500 mg and bulk. Please contact Fisher for quotes. Milnacipran hydrochloride (Savella) is a serotonin and norepinephrine reuptake inhibitor used to treat major depressive disorders. Milnacipran hydrochloride is an enantiomer of milnacipran, which is used to treat fibromyalgia. Milnacipran hydrochloride and milnacipran have been associated with a low rate of transient elevations in serum aminotransferase levels during treatment and with rare instances of clinically apparent acute liver injury with jaundice. Purity 100%