Oxazinanes
![eMolecules Pharmablock tert-butyl N-[(1S2S)-2-aminocyclobutyl]carbamate 1g 551123640 PBLL1453 1374222-18-0 [null] 186.255 C9H18N2O2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502695848.jpg-250.jpg)
eMolecules Pharmablock tert-butyl N-[(1S2S)-2-aminocyclobutyl]carbamate 1g 551123640 PBLL1453 1374222-18-0 [null] 186.255 C9H18N2O2
Pharmablock tert-butyl N-[(1S2S)-2-aminocyclobutyl]carbamate 1g 551123640 PBLL1453 1374222-18-0 [null] 186.255 C9H18N2O2
Medchemexpress LLC Bomedemstat dihydrochloride | 99.6% | 592.54 | 10 MG
Bomedemstat (IMG-7289) dihydrochloride is an orally active and irreversible lysine-specific demethylase 1 (LSD1) inhibitor. It increases H3K4 and H3K9 methylation, which then alters gene expression. This compound exhibits anti-cancer activities by inhibiting cancer cell proliferation and inducing apoptosis.
- Orally active and irreversible lysine-specific demethylase 1 (LSD1) inhibitor.
- Increases H3K4 and H3K9 methylation.
- Alters gene expression.
- Shows anti-cancer activities.
- Inhibits cancer cell proliferation.
- Induces apoptosis.
Cayman Chemical 3 4DIhydroxymndelIc AcId 250mg
An active metabolite of norepinephrine; scavenges superoxide radicals (IC50 = 130 nM) and reduces lipid peroxidation in cell-free assays; a chemoattractant for enterohemorrhagic E. coli; induces the expression of enterohemorrhagic E. coli virulence genes at 50 µM; increases the attachment of enterohemorrhagic E. coli to HeLa cells in vitro
Medchemexpress LLC N1,N1-dimethylpropane-1,2-diamine | 108-15-6 | MFCD00014812 | 99.3% | 102.18 | 500 MG
N1,N1-dimethylpropane-1,2-diamine is a laboratory chemical used in the manufacture of substances. It is intended for research use only and should be handled by experienced personnel. The product has not been fully validated for medical applications and is stable under recommended storage conditions.
- Laboratory chemicals
- Manufacture of substances
- Research use only
- Stable under recommended storage conditions
- Appearance: liquid, colorless to light yellow
Selleck Chemical LLC Epertinib hydrochloride
Epertinib hydrochloride (S-222611 hydrochloride) is a potent orally active reversible and selective tyrosine kinase inhibitor of EGFR HER2 and HER4 with IC50 of 1 48 nM 7 15 nM and 2 49 nM respectively Epertinib hydrochloride (S-222611 hydrochloride) exhibits antitumor activity
Apexbio Technology LLC PI-103 Hydrochloride 371935-79-4 10mM (in 1mL DMSO)
PI-103 Hydrochloride (CAS 371935-79-4) is a dual inhibitor targeting class I phosphatidylinositide 3-kinases (PI3K) and mammalian target of rapamycin (mTOR) It selectively inhibits PI3K isoforms p110 p110 p110 and mTOR with reported IC50 values of 0 002 M 0 003 M 0 003 M and 0 030 M respectively PI-103 effectively blocks the PI3K/Akt/mTOR pathway which is centrally involved in cell proliferation and survival signaling and is frequently dysregulated in cancer In various cellular models including leukemia hepatocellular carcinoma glioblastoma and neuroblastoma PI-103 suppresses pathway activation and inhibits cell proliferation It is widely used for investigating PI3K/Akt/mTOR signaling in oncology research
Cayman Chemical FR122047 hydrochloride
A selective COX-1 inhibitor (IC50 = 0.028 µM for the human enzyme); selective for COX-1 over COX-2 (IC50 = 65 µM); inhibits arachidonic acid, collagen, and ADP-induced platelet aggregation in human platelet-rich plasma (IC50 = 180-200 nM); unlike aspirin, it does not induce gastric damage at 100 mg/kg, p.o.; has an anti-inflammatory effect in a rat models of collagen-induced arthritis
Accela Chembio Inc 4-(4-bromophenyl)morpholine | 25g | 30483-75-1 | MFCD04112483 | 98% | Shelf Life: 1800 Days | Light Sensitive/n2
4-(4-bromophenyl)morpholine | 25g | 30483-75-1 | MFCD04112483 | 98% | Shelf Life: 1800 Days | Light Sensitive/n2
Cayman Chemical HA1077 hydrochloride
A potent inhibitor of ROCK2, PRK-2, MSK1, and MAPKAP-K1b with IC50 values of 1.9, 4, 5, and 15 µM, respectively; has been shown to reduce blood vessel constriction, decreases pulmonary arterial pressure, inhibit tumor angiogenesis, and improve insulin signaling in a diabetic rat model; drug forms are marketed for the treatment of pulmonary arterial hypertension and stable angina