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2H-Cho-Arg (trifluoroacetate) is a steroid-based cationic lipid that couples a 2H-cholesterol skeleton to an L-arginine head group. It forms complexes with plasmid DNA and is used to facilitate gene transfection in cultured cells.
Steroid-based cationic lipid with a 2H-cholesterol skeleton and L-arginine head group.
Forms stable complexes with plasmid DNA, reducing DNA migration in electrophoretic assays.
Facilitates transfection of reporter genes in cell lines such as H1299.
Cellular uptake involves lipid raft and caveolae-mediated endocytosis pathways.
Supplied as the trifluoroacetate salt in solution; recommended storage -20 °C.
Reported purity greater than 95%.
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