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(R)-4-Benzyl-2-oxazolidinone is an oxazolidinone-type auxiliary that enables highly stereoselective asymmetric alkylation reactions. It is applied in the total synthesis of natural products and pharmaceutical preparations. Especially in pharmaceutical research and development, it serves as a key precursor for the synthesis of aromatase inhibitors and can also be used in studies related to estrogen-dependent breast cancer.
Serves as the core chiral parent nucleus of aromatase inhibitors.
Inhibitory activity of derivatives is significantly superior to that of (S)-4-Benzyl-2-oxazolidinone.
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