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Filtered Search Results
Medchemexpress LLC 6''-chloro-4'-(3-chloro-2-fluorophenyl) dispiroindole-5'-carboxylic acid (3'R,4'S,5'R) | 1410737-09-5 | 98.0% | C23H21Cl2FN2O3 | 10MG
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MDM2-IN-1 (Compound 30) is a synthetic small-molecule inhibitor of the MDM2-p53 protein-protein interaction supplied for research use in oncology and related cell biology studies. It contains the trans configuration and is intended for in vitro and preclinical investigations, including osteosarcoma research.
- contains the trans configuration
- inhibits MDM2-p53 interaction in biochemical and cellular assays
- available as solid material and as a 10 mM solution in DMSO
- high purity (HPLC): 98.0%
- molecular formula C23H21Cl2FN2O3; molecular weight 463.33
- supplied with certificate of analysis and safety data sheet
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Apexbio Technology LLC SCH 79797 dihydrochloride 5mg
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SCH 79797 dihydrochloride (CAS 1216720-69-2) is a potent and selective non-peptide antagonist of protease-activated receptor 1 (PAR1) It inhibits the binding of thrombin receptor-activating peptide to PAR1 with an IC50 of 70 nM and displays a Ki of 35 nM for receptor modulation SCH 79797 dihydrochloride prevents thrombin-induced platelet aggregation with an IC50 of 3 M and demonstrates antiproliferative and pro-apoptotic effects as well as attenuation of myocardial ischemia/reperfusion injury The compound is utilized in biomedical research to study PAR1-mediated signaling in vascular smooth muscle cells endothelial cells and astrocytes
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Ambeed tertButyl 2aminoethyl carbama
tert-Butyl (2-aminoethyl)carbamate, 57260-73-8, 97%
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Sigma Aldrich Fine Chemicals Biosciences bisBenzimide H 33258 >=98% (HPLC and TLC) | 23491-45-4 | MFCD00012679 | 25MG
bisBenzimide H 33258 >=98% (HPLC and TLC) | Purity: >=98% (HPLC and TLC) | Mol Wt: 533.88 | 23491-45-4 | MFCD00012679 | 25MG
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Chem-Impex International, Inc. Triethylenediamine | MFCD00006689 | 100G
Triethylenediamine, MFCD00006689, 100G
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eMolecules 1010133-97-7 | 1-(Pyridin-3-yl)piperazine hydrochloride | MFCD21396210 | 250mg
Ambeed | 1-Boc-3-((Methylamino)methyl)piperidine | 100mg | 601095833 | A378914 | 1017356-25-0 | MFCD08061952 | 228.336 | C12H24N2O2
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Aobchem AOBCHEM
5001082247 2- 4-BUTOXY-3 5-DIMETHYLPHENYL
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Aobchem AOBCHEM
5001079735 1- 4-CHLORO-3 5-DIMETHYLPHENYL
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Aobchem AOBCHEM
5001082000 3 5-DIMETHYLPHENYL 4-ETHYL-1
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Aobchem AOBCHEM
5001079821 3-CHLORO-2 5-DIMETHYLPHENYL M
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Medchemexpress LLC 2-Aminoethyl diphenylborinate | 524-95-8 | 98.9% | 225.09 | 50 MG
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2-Aminoethyl diphenylborinate (2-APB) is a cell-permeable inhibitor of Inositol triphosphate receptor (IP3R) that also inhibits store-operated Ca2+ (SOC) channels and activates certain TRP channels. This compound has demonstrated inhibitory effects on vasospasm and, at high concentrations, exhibits specific anti-inflammatory and antioxidant effects in neural tissue. It is intended for research use only.
- Cell-permeable inhibitor of Inositol triphosphate receptor (IP3R)
- Inhibits store-operated Ca2+ (SOC) channels
- Activates some TRP channels (V1, V2, and V3)
- Exhibits inhibitory effects on vasospasm
- Provides anti-inflammatory and antioxidant effects in neural tissue
- Offers protective effects against ischemia-reperfusion induced damage
- Reduces oxidative stress and apoptosis from testicular ischemia-reperfusion injury
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Medchemexpress LLC Thalidomide-Piperazine-PEG2-NH2 diTFA | 99.7% | 701.57 | 100 MG
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Thalidomide-Piperazine-PEG2-NH2 diTFA is a synthesized E3 ligase ligand-linker conjugate. It incorporates a Thalidomide-based cereblon ligand and a linker, which are components utilized in PROTAC technology. This product is intended for research use only. PROTACs, or Proteolysis Targeting Chimeras, function by connecting two different ligands with a linker: one ligand binds to an E3 ubiquitin ligase, and the other targets a specific protein. This mechanism allows PROTACs to exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates Thalidomide-based cereblon ligand
- Utilized in PROTAC technology
- For research use only
- Functions by connecting two different ligands with a linker
- Exploits intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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Medchemexpress LLC 2-Aminoethyl diphenylborinate (2-APB) | 524-95-8 | 98.9% | 225.09 | 10 MG
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2-Aminoethyl diphenylborinate (2-APB) is a cell-permeable inhibitor of Inositol triphosphate receptor (IP3R). It also inhibits the store-operated Ca2+ (SOC) channel and activates some TRP channels (V1, V2 and V3). In addition, it has inhibitory effects on vasospasm. At high concentrations, it demonstrates specific anti-inflammatory and antioxidant effects in neural tissue.
- Cell-permeable inhibitor of inositol triphosphate receptor (IP3R)
- Inhibits store-operated Ca2+ (SOC) channel
- Activates some TRP channels (V1, V2 and V3)
- Exhibits inhibitory effects on vasospasm
- Displays specific anti-inflammatory and antioxidant effects in neural tissue at high concentrations
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Accela Chembio Inc 4-(4-boc-piperazino)phenylboronic Acid Pinacol Ester | 1g | 470478-90-1 | MFCD06411544 | 97+% | Shelf Life: 1260 Days | Light Sensitive/n2
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4-(4-boc-piperazino)phenylboronic Acid Pinacol Ester | 1g | 470478-90-1 | MFCD06411544 | 97+% | Shelf Life: 1260 Days | Light Sensitive/n2
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Ambeed 1-METHYLPIPERAZINE
NC3840975 1-METHYLPIPERAZINE
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