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Filtered Search Results
Apexbio Technology LLC Dexrazoxane HCl (ICRF-187, ADR-529) 149003-01-0 10mM (in 1mL DMSO)
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Dexrazoxane HCl (ICRF-187 ADR-529) is a small-molecule inhibitor targeting topoisomerase II It is designed to inhibit topoisomerase II activity and sequester intracellular iron thereby reducing DNA strand cleavage and mitigating iron-dependent oxidative stress Dexrazoxane HCl exerts its biological activity primarily through intracellular iron chelation and inhibition of topoisomerase II which attenuates reactive oxygen species formation and stabilizes DNA structure Based on these pharmacological properties Dexrazoxane HCl holds research potential in investigating cardioprotective strategies particularly against anthracycline-induced cardiotoxicity
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Aobchem AOBCHEM
5000940569 3- 3 4-DIMETHYLPHENYL TETRAHYD
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Aobchem AOBCHEM
5001037703 3- 1-HYDROXY-1-METHYLETHYL BEN
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Aobchem AOBCHEM
5001040755 4-BROMO-2 3-DIMETHYLPHENYL ME
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Aobchem AOBCHEM
5000945446 1- 4-BUTOXY-3 5-DIMETHYLPHENYL
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Medchemexpress LLC Ethyl 4-((1-hydroxy-2-phenyl-1H-indol-3-yl)(pyridin-2-yl)methyl)piperazine-1-carboxylate | 622795-76-0 | 98.0% | 456.54 g/mol | C27H28N4O3 | 10MG
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PIP-199 is a small-molecule inhibitor that selectively disrupts the RMI (RecQ-mediated genome instability protein) core complex/MM2 protein-protein interaction. It is supplied as a research reagent (CAS 622795-76-0) with molecular formula C27H28N4O3 and is used in studies of DNA repair and in research on sensitizing tumor cells to DNA crosslinking agents.
- Selective inhibitor of RMI-MM2 protein-protein interaction.
- Useful for studying DNA repair and tumor sensitization to crosslinking agents.
- Characterized by a molecular weight of 456.54 g/mol and formula C27H28N4O3.
- Purity typically 98.0% for research applications.
- Available in small-scale quantities suitable for laboratory experiments.
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Medchemexpress LLC 2-((2-Aminoethyl)amino)acetic acid | 24123-14-6 | 99.9% | 118.14 | 250 MG
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2-((2-Aminoethyl)amino)acetic acid is a Glycine derivative. This chemical is primarily used as a laboratory chemical and in the manufacture of substances. Amino acids and their derivatives, such as this product, are commonly recognized as beneficial ergogenic dietary substances. They influence the secretion of anabolic hormones, supply fuel during exercise, improve mental performance during stress-related tasks, and help prevent exercise-induced muscle damage.
- Used as a laboratory chemical
- Used in the manufacture of substances
- Influences the secretion of anabolic hormones
- Provides fuel during exercise
- Supports mental performance during stress-related tasks
- Helps prevent exercise-induced muscle damage
- Store at 4°C, protect from light
- For research use only
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Medchemexpress LLC 2-Aminoethyl diphenylborinate | 524-95-8 | 98.9% | 225.09 | 25 MG
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2-Aminoethyl diphenylborinate (2-APB) is a cell-permeable inhibitor of Inositol triphosphate receptor (IP3R). It also inhibits the store-operated Ca2+ (SOC) channel and activates some TRP channels (V1, V2 and V3). Additionally, it has inhibitory effects on vasospasm. At high concentrations, it exhibits specific anti-inflammatory and antioxidant effects in neural tissue. This product is for research use only.
- Inhibits inositol triphosphate receptor (IP3R)
- Inhibits store-operated Ca2+ (SOC) channel
- Activates some TRP channels (V1, V2, and V3)
- Inhibitory effects on vasospasm
- Exhibits specific anti-inflammatory and antioxidant effects in neural tissue (at high concentrations)
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Aobchem AOBCHEM
5001035030 2 5-DIMETHYLPHENYL -2-PYRIDIN
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Medchemexpress LLC Aspartyl-alanyl-diketopiperazine | 110954-19-3 | 98.9% | 186.17 g/mol | C7H10N2O4 | 1 ML
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Aspartyl-alanyl-diketopiperazine (DA-DKP) is a cyclic dipeptide derived from the N-terminus of human albumin with reported immunomodulatory activity. It modulates inflammatory immune responses and is supplied for laboratory research as a solid or as a ready-to-use solution.
- Purity 98.87%.
- Molecular weight 186.17 g/mol.
- Chemical formula C7H10N2O4.
- CAS number 110954-19-3.
- Physical form solid, white to off-white.
- Also available as a 10 mM solution in DMSO, 1 mL.
- Typical solid package sizes 5 mg, 10 mg, 25 mg, 50 mg, 100 mg.
- For research use only; not for human or clinical use.
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Cayman Chemical Dexrazoxane 50mg
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An intracellular iron chelator and an inhibitor of topoisomerase IIα that is highly protective in reducing anthracycline-induced cardiotoxicity and extravasation injury; scavenges hydroxyl (IC50 = 2.1 mM), superoxide (IC50 = 0.4 mM), lipid (IC50 = 4.4 mM), DPPH (IC50 = 3.5 μM), and ABTS+ (IC50 = 3.8 mM) free radicals
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Apexbio Technology LLC N4-Methyl-dCTP(Synonyms: N4-Methyl-2'-deoxycytidine-5'-triphosphate, N4-Me-dCTP, 4-Methyl-dCTP), 50ul (100 mM).
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N4-Methyl-dCTP is a cytosine-derived modified deoxynucleoside triphosphate capable of being enzymatically incorporated into DNA strands thereby introducing cytosine methylation modifications at specific genomic sites DNA methylation at the N4 position of cytosine is observed naturally across both prokaryotic and eukaryotic organisms and influences processes such as epigenetic gene expression regulation DNA replication and DNA damage repair Researchers use N4-Methyl-dCTP to incorporate defined methylation modifications enabling investigation into methylation-specific DNA-binding protein interactions DNA methylation patterning analyses and functional studies of epigenetic modification pathways
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Aobchem AOBCHEM
5000873150 2- 3- CYCLOHEXYLMETHYL PHENYL
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000734927 TERT-BUTYL 4-PIPER 500MG
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Selleck Chemical LLC H-1152 dihydrochloride
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H-1152 dihydrochloride (2HCl) is a membrane-permeable and selective inhibitor of Rho-associated protein kinase (ROCK) H-1152 inhibits ROCK2 PKA PKC PKG AuroraA and CaMK2 with IC50 of 0 0120 M 3 03 M 5 68 M 0 360 M 0 745 M and 0 180 M respectively
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