Piperazines
Organic heterocyclic compounds that consist of a six-membered ring with four carbon atoms and two nitrogen atoms at opposite positions in the ring.
Quantity
- (1)
- (186)
- (4)
- (1)
- (1)
- (13)
- (9)
- (29)
- (4)
- (19)
- (1)
- (1)
- (3)
- (6)
- (89)
- (7)
- (2)
- (5)
- (2)
- (65)
- (1)
- (1)
- (145)
- (2)
- (4)
- (1)
- (6)
- (1)
- (11)
- (15)
- (3)
- (1)
- (1)
- (1)
Molecular Weight (g/mol)
- (2)
- (1)
- (1)
- (1)
- (1)
- (4)
- (8)
- (2)
- (5)
- (1)
- (1)
- (2)
- (1)
- (3)
- (4)
- (2)
- (2)
- (2)
- (7)
- (3)
- (3)
- (6)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (7)
- (1)
- (1)
- (2)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (4)
- (4)
- (7)
- (8)
- (1)
- (5)
- (5)
- (1)
- (2)
- (1)
- (3)
- (3)
- (6)
- (1)
- (1)
- (1)
- (3)
- (1)
- (2)
- (3)
- (3)
- (2)
- (1)
- (2)
- (2)
- (1)
- (4)
- (7)
- (1)
- (1)
- (1)
- (4)
- (4)
- (1)
- (5)
- (2)
- (4)
- (1)
- (2)
- (2)
- (5)
- (4)
- (3)
- (2)
- (3)
- (1)
- (2)
- (1)
- (2)
- (1)
- (4)
- (2)
- (2)
- (8)
- (2)
- (2)
- (2)
- (1)
- (3)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (1)
- (1)
- (4)
- (4)
- (3)
- (2)
- (1)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (4)
- (5)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (3)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (4)
- (1)
- (2)
- (1)
- (1)
- (2)
- (3)
- (1)
- (1)
- (3)
- (4)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (9)
- (9)
- (1)
- (9)
- (2)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (1)
- (2)
- (3)
- (4)
- (8)
- (1)
- (1)
- (1)
- (3)
- (2)
- (2)
- (1)
- (2)
- (3)
- (1)
- (1)
- (5)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (3)
- (2)
- (2)
- (3)
- (2)
- (1)
- (1)
- (1)
- (2)
- (5)
- (4)
- (2)
- (2)
- (1)
- (1)
- (3)
- (2)
- (2)
- (3)
- (2)
- (6)
- (2)
- (1)
- (1)
- (2)
- (1)
- (2)
- (2)
- (3)
- (3)
- (1)
- (6)
- (1)
- (1)
- (4)
- (5)
- (1)
- (2)
- (8)
- (1)
- (2)
- (1)
- (1)
- (3)
- (2)
- (3)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (4)
- (4)
- (4)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (1)
- (1)
- (7)
- (3)
- (6)
- (2)
- (4)
- (5)
- (1)
- (1)
Percent Purity
- (1)
- (2)
- (4)
- (1)
- (2)
- (2)
- (23)
- (20)
- (51)
- (7)
- (11)
- (10)
- (2)
- (15)
- (3)
- (3)
- (2)
- (3)
- (8)
- (4)
- (6)
- (1)
- (26)
- (8)
- (201)
- (2)
- (7)
- (63)
- (5)
- (1)
- (2)
- (43)
Physical Form
- (2)
- (7)
- (99)
- (2)
- (2)
- (3)
- (3)
- (7)
- (4)
- (63)
- (2)
- (2)
- (2)
- (5)
- (39)
- (1)
- (72)
Boiling Point
- (2)
- (1)
- (1)
- (2)
- (1)
- (3)
- (1)
- (3)
- (3)
- (2)
- (1)
- (7)
- (3)
- (2)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (3)
- (1)
- (1)
- (2)
- (2)
- (5)
- (3)
- (2)
- (2)
- (2)
- (2)
- (3)
- (2)
- (3)
- (4)
- (2)
- (2)
- (2)
- (2)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (3)
- (4)
- (3)
- (1)
- (1)
- (3)
- (2)
- (2)
- (1)
- (3)
- (2)
- (2)
- (3)
- (2)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (3)
- (2)
- (2)
- (2)
- (1)
- (2)
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Aobchem AOBCHEM
5000913312 3-FLUORO-2 4-DIMETHYLPHENYL
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437
Ambeed AMBEED
5000896247 2-PHENYLACETIMIDAMIDE HY 250MG
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438
Aobchem AOBCHEM
5000913242 2-FLUORO-3 5-DIMETHYLPHENYL M
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439
Aobchem AOBCHEM
5000913742 5- 2 6-DIMETHYLPHENYL -N-METHY
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440
Aobchem AOBCHEM
5000913748 5- 2 5-DIMETHYLPHENYL -N-METHY
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441
Aobchem AOBCHEM
5000916353 3- 3 5-DIMETHYLPHENYL -3-HYDRO
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442
Chemscene CHEMSCENE
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5000578643 1-3-METHOXYPHENYL PIPERAZI 10G
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443
Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000758096 METHYL N-BOC-4-PIPER 500MG
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444
Aobchem AOBCHEM
5000910660 1- 4-CHLORO-3 5-DIMETHYLPHENYL
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445
Aobchem AOBCHEM
5000911644 2 5-DIMETHYLPHENYL TRIMETHYLS
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446
Aobchem AOBCHEM
5000914775 4-METHOXY-2 5-DIMETHYLPHENYL
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447
Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000772793 TERT-BUTYL 4-PIPERA 1G
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448
Chemscene CHEMSCENE
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5000577100 2-2 5-DIMETHYLPHENYL ACET 500G
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449
Chemscene CHEMSCENE
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5000577557 S-1-BOC-3-METHYLPIPERAZINE 15G
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450
Medchemexpress LLC Carm1 degrader-1 hydrochloride | 3032785-00-2 | 99.4% | 1316.14 | C71H99ClN12O8S | 10 MG
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CARM1 degrader-1 hydrochloride is a proteolysis-targeting chimera (PROTAC) that induces VHL- and proteasome-dependent degradation of co-activator associated arginine methyltransferase 1 (CARM1). It has a reported DC50 of 8.1 nM and inhibits methylation of CARM1 substrates, which has been shown to reduce breast cancer cell migration. The compound is provided as a hydrochloride salt and is characterized by a high reported purity for research use.
- Potent PROTAC degrader of CARM1 with a low nanomolar DC50.
- Acts through VHL- and proteasome-dependent degradation pathways.
- Reduces methylation of CARM1 substrates such as PABP1 and BAF155.
- Demonstrated effect on breast cancer cell migration in preclinical assays.
- Provided as a hydrochloride salt with high reported purity.
- Available in small research quantities suitable for in vitro studies.
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