Piperidines
Selleck Chemical LLC Encenicline (EVP-6124) hydrochloride S2957-5mg
Encenicline (EVP-6124) hydrochloride is a selective 7 nicotinic acetylcholine receptor partial agonist improves memory performance by potentiating the acetylcholine response of 7 nicotinic acetylcholine receptors
Apexbio Technology LLC Copanlisib dihydrochloride 1402152-13-9 50mg
Copanlisib dihydrochloride (CAS 1402152-13-9) is a small-molecule inhibitor that selectively targets phosphoinositide 3-kinase (PI3K) isoforms and By inhibiting these PI3K subunits copanlisib disrupts PI3K/AKT signaling pathways that regulate cellular proliferation and survival leading to reduced tumor cell growth and induction of apoptosis This compound is utilized in biomedical research to investigate PI3K-mediated oncogenic processes particularly in studies related to relapsed or refractory follicular lymphoma and other hematologic malignancies dependent on aberrant PI3K activity
eMolecules Ambeed / Benzyl 3-aminopiperidine-1-carboxylate hydrochloride / 250mg / 552666762 / A235752 / / 960541-42-8 / MFCD04038445 / 270.760 / C13H19ClN2O2
Ambeed / Benzyl 3-aminopiperidine-1-carboxylate hydrochloride / 250mg / 552666762 / A235752 / / 960541-42-8 / MFCD04038445 / 270.760 / C13H19ClN2O2
MSC Made in USA SSMS-250-632-N #6-32 UNC, 1/4" Length of Thread, Soft Tip Point Set Screw Nylon
Made in USA SSMS-250-632-N #6-32 UNC, 1/4" Length of Thread, Soft Tip Point Set Screw Nylon
Apexbio Technology LLC Flupenthixol dihydrochloride 2413-38-9 10mg
Flupenthixol dihydrochloride (CAS 2413-38-9) is a thioxanthene-derived small molecule primarily developed as an antipsychotic agent It functions as a dopamine D2 receptor antagonist modulating dopaminergic neurotransmission in the central nervous system In vitro assays demonstrate minimum inhibitory concentrations (MICs) of 10 100 g/mL against most bacterial strains with inhibitory effects observed at lower concentrations for select species including Staphylococcus aureus and Vibrio cholerae In vivo studies show that flupenthixol significantly reduces bacterial load and increases survival in murine infection models Clinically it has been evaluated for the management of schizophrenia and mood disorders supporting its utility in neuropharmacological and antimicrobial research
Chem-Impex International, Inc. 4-Amino-1-methylpiperidine | 41838-46-4 | MFCD01570549 | 5G
4-Amino-1-methylpiperidine, 41838-46-4, MFCD01570549, 5G
Medchemexpress LLC CCT128930 hydrochloride | 2453324-32-6 | 99.0% | C18H21Cl2N5 | 10MG
CCT128930 hydrochloride is the hydrochloride salt of a selective ATP-competitive AKT inhibitor supplied as a powder for research use. It is employed in cellular assays to probe PI3K/Akt/mTOR signaling, induce cell cycle arrest, and study autophagy; handle and store according to the product SDS and COA.
Medchemexpress LLC HY-100546A 5mg Medchemexpress, GSK-LSD1 Dihydrochloride CAS:2102933-95-7 Purity:>98%
Medchemexpress, HY-100546A 5mg GSK-LSD1 Dihydrochloride CAS:2102933-95-7 GSK-LSD1 Dihydrochloride is a potent, selective and irreversible lysine specific demethylase 1 ( LSD1 ) inhibitor with an IC 50 of 16 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC GBR 12935 dihydrochloride 67469-81-2 100mg
GBR 12935 dihydrochloride is a small-molecule inhibitor targeting the dopamine transporter (DAT) It is designed to inhibit DAT-mediated dopamine reuptake thereby modulating dopaminergic signaling and increasing extracellular dopamine levels GBR 12935 dihydrochloride exerts its biological activity primarily through direct blockade of neuronal dopamine uptake at the synaptic cleft Based on these pharmacological properties GBR 12935 dihydrochloride holds research potential in studies of dopaminergic signaling reward pathways addiction behaviors dopamine-related neurodegeneration and dopamine transporter function
![Medchemexpress LLC (3R,4R)-4-amino-1-[[4-(3-methoxyanilino)pyrrolo[2,1-f]triazin-5-yl]methyl]piperidin-3-ol | 859853-30-8 | MFCD18633295 | 99.7% | 368.43 g/mol | C19H24N6O2 | 2 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00132390-HY-10333-2MG.JPG-250.jpg)
Medchemexpress LLC (3R,4R)-4-amino-1-[[4-(3-methoxyanilino)pyrrolo[2,1-f]triazin-5-yl]methyl]piperidin-3-ol | 859853-30-8 | MFCD18633295 | 99.7% | 368.43 g/mol | C19H24N6O2 | 2 MG
BMS-690514 is a small-molecule, orally active tyrosine kinase inhibitor that targets epidermal growth factor receptors (EGFR/HER family) and vascular endothelial growth factor receptors (VEGFR). It has been investigated in preclinical and clinical studies for treatment of solid tumors and is supplied for research use only.
- Potent inhibition of EGFR, HER2, and HER4 (IC50 ≈5, 20, 60 nM).
- Activity against VEGFR family members and additional kinases.
- Orally active with documented preclinical bioavailability in multiple species.
- High purity suitable for research (99.68%).
- Molecular formula C19H24N6O2; molecular weight 368.43 g/mol.
- Intended for laboratory research and preclinical studies only.
Apexbio Technology LLC SB 747651A dihydrochloride 10mg
SB 747651A dihydrochloride is a small-molecule inhibitor targeting mitogen- and stress-activated protein kinase 1 (MSK1) It is designed to selectively inhibit MSK1 activity thereby interfering with phosphorylation-mediated signal transduction pathways downstream of MSK1 SB 747651A dihydrochloride exerts its biological activity primarily through competitive inhibition of MSK1 kinase disrupting phosphorylation of the transcription factor CREB and histone H3 Based on these pharmacological properties SB 747651A dihydrochloride holds research potential in inflammation pathways stress-responsive gene regulation cellular proliferation and differentiation and neuronal plasticity
![Medchemexpress LLC 3-(1-(4-chlorophenyl)-4-((1H-pyrrolo[2,3-b]pyridin-4-yl)amino)piperidin-1-yl)propan-1-ol hydrochloride | 2453324-32-6 | MFCD13177916 | 99.0% | 378.30 g·mol⁻¹ | C18H21Cl2N5 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000262961.png-250.jpg)
Medchemexpress LLC 3-(1-(4-chlorophenyl)-4-((1H-pyrrolo[2,3-b]pyridin-4-yl)amino)piperidin-1-yl)propan-1-ol hydrochloride | 2453324-32-6 | MFCD13177916 | 99.0% | 378.30 g·mol⁻¹ | C18H21Cl2N5 | 5 MG
CCT128930 hydrochloride is the hydrochloride salt of a potent and selective AKT (protein kinase B) inhibitor for preclinical research. Supplied as a solid, it is intended for biochemical and cellular studies where high potency and defined physicochemical properties are required.
- Potent and selective AKT inhibitor (AKT IC50 ≈ 6 nM).
- Hydrochloride salt; solid, white to yellow.
- High purity (≈99.0%).
- Molecular formula C18H21Cl2N5; molecular weight 378.30 g·mol⁻¹.
- Soluble in DMSO up to 20 mg/mL with warming and sonication.
- Recommended storage sealed, away from moisture; in solution -80°C (≤6 months).
- Supplied in small research quantities suitable for assay development.
Apexbio Technology LLC Octenidine (dihydrochloride) 70775-75-6 1g
Octenidine dihydrochloride (CAS 70775-75-6) is a small-molecule inhibitor designed to disrupt microbial membrane integrity thereby inhibiting bacterial proliferation Octenidine dihydrochloride exerts its biological activity primarily through disruption of microbial membrane integrity In in vitro studies Octenidine dihydrochloride demonstrates inhibitory activity against diverse Gram-positive and Gram-negative bacterial strains with reported IC50 values typically ranging from 1 to 10 g/mL depending on test organisms and experimental conditions Based on these pharmacological properties Octenidine dihydrochloride holds research potential in infection control wound management and microbiological assay applications