Piperidines
Medchemexpress LLC HY-120934 5mg Medchemexpress, C25-140 CAS:1358099-18-9 Purity:>98%
Medchemexpress, HY-120934 5mg C25-140 CAS:1358099-18-9 C25-140, a first-in-class, fairly selective TRAF6-Ubc13 inhibitor, directly binds to TRAF6, and blocks the interaction of TRAF6 with Ubc13. C25-140 lowers TRAF6 activity, reduces NF-κB activation, and combats autoimmunity [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-101493 5mg Medchemexpress, SUN11602 CAS:704869-38-5 Purity:>98%
Medchemexpress, HY-101493 5mg SUN11602 CAS:704869-38-5 SUN11602 is a novel aniline compound with basic fibroblast growth factor-like activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-101488 100mg Medchemexpress, CC-885 CAS:1010100-07-8 Purity:>98%
Medchemexpress, HY-101488 100mg CC-885 CAS:1010100-07-8 CC-885 is a cereblon ( CRBN ) modulator with potent anti-tumour activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-10021 100mg Medchemexpress, Varenicline (Tartrate) CAS:375815-87-5 Purity:>98%
Medchemexpress, HY-10021 100mg Varenicline (Tartrate) CAS:375815-87-5 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-100228A 5mg Medchemexpress, SKF89976A (hydrochloride) CAS:85375-15-1 Purity:>98%
Medchemexpress, HY-100228A 5mg SKF89976A (hydrochloride) CAS:85375-15-1 SKF89976A hydrochloride is a selective GABA transporter ( GAT-1 ) inhibitor with IC 50 s of 0.28 μM, 137.34 μM and 202.8 μM for GAT-1, GAT-2 and GAT-3 in CHO cells, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Rho-kinase-IN-1 | 1035094-83-7 | MFCD18633216 | 99.9% | 352.50 g·mol⁻¹ | C20H24N4S | 25 MG
Rho-Kinase-IN-1 is a selective Rho-associated protein kinase (ROCK) inhibitor used for laboratory research. Reported in patent US20090325960A1 (compound 1.008), it exhibits potent activity against ROCK1 and ROCK2 and is used to study signaling pathways involved in cell proliferation, cytoskeletal remodeling, edema, and inflammation. For research use only.
- Potent inhibition of ROCK1 and ROCK2 (Ki ≈ 30.5 nM and 3.9 nM).
- High purity suitable for biochemical and cellular assays (99.91%).
- Molecular formula C20H24N4S and molecular weight 352.50 g·mol⁻¹.
- Available as solid and as DMSO solution for assay flexibility.
- Supplied with datasheet and SDS for safety and handling information.
Apexbio Technology LLC Avibactam sodium 1192491-61-4 10mg
Avibactam sodium (1192491-61-4) is a small-molecule inhibitor targeting bacterial -lactamase enzymes including CTX-M-15 and TEM-1 It is designed to inhibit -lactamase activity thereby preventing the hydrolysis of -lactam antibiotics Avibactam sodium exerts its biological activity primarily through reversible covalent non- -lactam inhibition of its targets In in vitro studies avibactam sodium demonstrates inhibitory activity with IC50 values of 5 nM for CTX-M-15 and 8 nM for TEM-1 Based on these pharmacological properties avibactam sodium holds research potential in studies of combination therapy for bacterial infections involving -lactamase-producing Gram-negative pathogens
Medchemexpress LLC Rho-kinase-IN-1 | 1035094-83-7 | 99.9% | 352.50 g/mol | C20H24N4S | 100 MG
Rho-Kinase-IN-1 is a small-molecule Rho-associated kinase (ROCK) inhibitor used in biochemical and cellular research. It demonstrates potent activity against ROCK isoforms (Ki = 30.5 nM for ROCK1; Ki = 3.9 nM for ROCK2) and is employed in studies of cell proliferation, tissue remodeling, vascular permeability, and inflammatory processes. Analytical documentation is available from the supplier.
Medchemexpress LLC HY-130683 5mg Medchemexpress, Lenalidomide-propargyl-C2-NH2 (hydrochloride) CAS: Purity:>98%
Medchemexpress, HY-130683 5mg Lenalidomide-propargyl-C2-NH2 (HCl) CAS: Lenalidomide-propargyl-C2-NH2 hydrochloride incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase, and a linker. Lenalidomide-propargyl-C2-NH2 hydrochloride can be used to design the PROTAC MD-224 (HY-114312). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
![Chemscene ChemScene | 2-(1'-(tert-Butoxycarbonyl)-2,3-dihydrospiro[indene-1,4'-piperidin]-3-yl)acetic acid | 250MG | CS-0038787 | 0.97 | 185526-66-3| MFCD08461262 | 345.44](https://assets.fishersci.com/TFS-Assets/CCG/product-images/CS-0038787.JPG-250.jpg)
Chemscene ChemScene | 2-(1'-(tert-Butoxycarbonyl)-2,3-dihydrospiro[indene-1,4'-piperidin]-3-yl)acetic acid | 250MG | CS-0038787 | 0.97 | 185526-66-3| MFCD08461262 | 345.44
ChemScene | 2-(1'-(tert-Butoxycarbonyl)-2,3-dihydrospiro[indene-1,4'-piperidin]-3-yl)acetic acid | 250MG | CS-0038787 | 0.97 | 185526-66-3| MFCD08461262 | 345.44
Medchemexpress LLC Piperidine-4-carboxamide-d9 | 1219803-20-9 | 98.2% | 137.23 | 1 MG
Piperidine-4-carboxamide-d9 is the deuterium labeled Piperidine-4-carboxamide. It is for research use only and not sold to patients. Deuteration has gained attention due to its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Chembridge Corporation TERT-BUTYL 4-AMINOPIPERIDINE-1
tert-butyl 4-amino-1-piperidinecarboxylate hydrochloride; CAS: 189819-75-8
Medchemexpress LLC ERRα ligand-linker conjugates 1 | 00-00-0 | 98.8% | C24H20F9N3O5 | 10MG
ERRα ligand-linker conjugate combines an ERRα-targeting ligand with a PROTAC-compatible linker to serve as a building block for synthesis of ERRα-directed degraders and related conjugates. Supplied as a solid with documented purity, molecular properties, and recommended storage for research applications.
- Designed for use in PROTAC synthesis and conjugation.
- High purity: 98.8%.
- Molecular weight: 601.42 g·mol⁻¹.
- Molecular formula: C24H20F9N3O5.
- Soluble in DMSO up to 200 mg/mL; ultrasonic may be needed.
- Appearance: light yellow to yellow solid.
- Recommended storage: store under nitrogen at -20°C; in solution keep at -80°C for long-term.
eMolecules Medchem Express / Mutant IDH1-IN-1 / 5mg / 446261328 / HY-12475 / / 1355326-21-4 / MFCD28385853 / 498.602 / C30H31FN4O2
Medchem Express / Mutant IDH1-IN-1 / 5mg / 446261328 / HY-12475 / / 1355326-21-4 / MFCD28385853 / 498.602 / C30H31FN4O2