Piperidines
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eMolecules 2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)thiazole-4-carboxylic acid | 668484-45-5 | MFCD13193290 | 250mg
Ambeed | 2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)thiazole-4-carboxylic acid | 250mg | 600847011 | A750294 | | 668484-45-5 | MFCD13193290 | 313.370 | C13H19N3O4S
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Medchemexpress LLC K-Ras-PDE -IN-1 5mg | 1841464-21-8 | 447.50 g/mol | C25H26FN5O2 | 5 MG
K-Ras-PDEδ-IN-1 is a small-molecule competitive inhibitor that binds the farnesyl binding pocket of PDEδ and disrupts PDEδ-K-Ras interaction. It is provided for research use in biochemical and cellular studies and is characterized by nanomolar affinity and high chemical purity. Follow supplier solubility and handling guidance when preparing solutions for in vitro or in vivo use.
- Binds the PDEδ farnesyl pocket with a Kd of ~8 nM.
- High chemical purity (≈99.6% as supplied).
- Soluble in DMSO (12.5 mg/mL); ultrasonic recommended for dissolution.
- Formulation guidance provided for in vivo suspension (10% DMSO, 40% PEG300, 5% Tween-80, 45% saline).
- Available in small research pack sizes suitable for biochemical assays.