Piperidines
Medchemexpress LLC HY-12334 5mg Medchemexpress, HTH-01-015 CAS:1613724-42-7 Purity:>98%
Medchemexpress, HY-12334 5mg HTH-01-015 CAS:1613724-42-7 HTH-01-015 is a selective NUAK1/ARK5 inhibitor (IC50 is 100 nM). HTH-01-015 inhibits NUAK1 with >100-fold higher potency than NUAK2 (IC50 of >10 μM). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC HTH-01-015(Synonyms: HTH01015, WZ4003, NUAK1 inhibitor WZ4003, NUAK1-IN-1, NUAK1 inhibitor, WZ-4003), 10mg, CAS: 1613724-42-7.
HTH-01-015 (CAS 1613724-42-7) is a highly selective inhibitor targeting the NUAK1 kinase exhibiting potent inhibitory activity with an IC50 of approximately 100 nM It specifically blocks NUAK1-mediated phosphorylation of MYPT1 at Ser445 with negligible off-target effects among a comprehensive panel of 139 other kinases Cellular studies demonstrate that treatment with HTH-01-015 reduces migration of mouse embryonic fibroblasts (MEFs) suppresses proliferation in U2OS and MEF cell lines at concentrations around 10 M and significantly inhibits invasion of U2OS cells within 3D Matrigel transwell assays This compound serves as a useful research tool for investigating NUAK1-related signaling pathways in cancer biology and cellular dynamics
eMolecules (3S)-piperidine-3-carboxamide hydrochloride | 1026661-43-7 | MFCD22415259 | 1g
Pharmablock (USA) Inc | (3S)-piperidine-3-carboxamide hydrochloride | 1g | 254798928 | PB00915-01 | | 1026661-43-7 | MFCD22415259 | 164.630 | C6H13ClN2O
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