Piperidines
Apexbio Technology LLC BMS-790052 dihydrochloride 1009119-65-6 5mg
BMS-790052 dihydrochloride (CAS 1009119-65-6) is a small-molecule inhibitor targeting hepatitis C virus (HCV) nonstructural protein 5A (NS5A) a zinc-binding protein essential for viral RNA replication It is designed to suppress viral replication by specifically interacting with NS5A BMS-790052 dihydrochloride exerts its biological activity primarily through NS5A inhibition In cell-based replicon assays using genotypes 1a 1b and hybrid genotype 5a BMS-790052 dihydrochloride demonstrates potent inhibitory activity with EC50 values ranging from approximately 9 to 50 pM for genotypes 1a and 1b and from 3 to 7 pM for genotype 5a hybrid replicons Based on these pharmacological properties BMS-790052 dihydrochloride holds research potential in antiviral studies targeting diverse HCV genotypes
