Pyrans
Apexbio Technology LLC Octyl-α-ketoglutarate 876150-14-0 10mg (solution)
Octyl- -ketoglutarate is a membrane-permeable derivative of -ketoglutarate a substrate required for prolyl hydroxylases (PHDs) enzymes regulating the stability of hypoxia-inducible factor-1 (HIF-1 ) through oxygen-dependent hydroxylation Intracellular delivery by octyl conjugation enhances cellular -ketoglutarate availability enabling the restoration of PHD enzymatic function compromised by elevated succinate or fumarate Research indicates its utility in cellular models with impaired TCA-cycle enzymes such as IDH1 mutations facilitating the study of hypoxic signaling pathways and tumor cell pseudohypoxia responses
Medchemexpress LLC γ-Carboxy-DL-glutamic acid | 56271-99-9 | 98.0% | 191.14 g·mol⁻1 | C6H9NO6 | 25 MG
γ-Carboxy-DL-glutamic acid is an optically active glutamic acid derivative supplied as a powder for research use. It has the molecular formula C6H9NO6, molecular weight 191.14 g·mol⁻1, and a reported purity of 98.0%. Documentation including a datasheet, certificate of analysis, and safety data sheet is available from the manufacturer.
eMolecules 2-methyltetrahydropyran-4-amine;hydrochloride | 827046-87-7 | | 1g
Pharmablock - Stock | 2-methyltetrahydropyran-4-amine;hydrochloride | 1g | 521633028 | PB90890-1 | | 827046-87-7 | | 151.630 | C6H14ClNO
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Medchemexpress LLC (2R)-octyl-α-hydroxyglutarate | 1391194-67-4 | MFCD30735809 | 99.9% | 260.33 | C13H24O5 | 50 MG
(2R)-Octyl-α-hydroxyglutarate (CAS 1391194-67-4) is a membrane-permeable ester derivative of the oncometabolite D-2-hydroxyglutarate, provided for laboratory research use. It is used as a cell-permeable precursor to study metabolic and epigenetic effects mediated by 2-hydroxyglutarate in cultured cells.
- Cell-permeable ester derivative of D-2-hydroxyglutarate.
- Useful for investigating IDH mutation-related metabolic pathways.
- Supplied at high purity suitable for biochemical and cellular assays.
- Available in small milligram pack sizes for laboratory experiments.
- For research use only; not for human or clinical use.