Pyrazines
TARGETMOL CHEMICALS INC HDAC-IN-57 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. HDAC-IN-57 is an orally active pan-inhibitor of histone deacetylase (HDAC) inhibiting HDAC1 HDAC2 HDAC6 and HDAC8 with IC50 values of 2.07 nM 4.71 nM 2.4 nM and 107 nM respectively. HDAC-IN-57 inhibits LSD1 with an IC50 value of 1.34 uu. HDAC-IN-57 has anti-tumor activity and can induce apoptosis. purity: 98%
Apexbio Technology LLC 2'-O-Methyl-CTP(Synonyms: 2'-O-Methylcytidine-5'-triphosphate, 2'-OMe-CTP, 2'-O-Methyl CTP, 2'-Methoxy CTP), 10ul (100 mM).
2 -O-Methyl-CTP is a chemically modified analog of cytidine triphosphate (CTP) characterized by methyl substitution at the 2 -hydroxyl position of the ribose sugar This modification confers increased resistance against nuclease-mediated degradation when incorporated into RNA transcripts enhancing RNA stability It is commonly employed in biomedical research for investigating RNA structure-function relationships assessing RNA stability and synthesizing siRNA or miRNA analogs utilized in RNA interference (RNAi) studies
Apexbio Technology LLC SCR7 pyrazine 14892-97-8 10mg
SCR7 pyrazine (CAS 14892-97-8) is a small-molecule inhibitor of DNA ligase IV a critical enzyme in the nonhomologous end-joining (NHEJ) pathway responsible for repairing DNA double-strand breaks (DSBs) By disrupting the DNA binding activity of ligase IV SCR7 impedes the NHEJ-mediated repair process leading to reduced cell viability and increased apoptosis In cellular assays SCR7 demonstrated dose-dependent inhibition of proliferation in various cancer cell lines with reported IC50 values ranging from 8 5 to 120 M Additionally in mouse models SCR7 administration suppressed tumor growth and enhanced sensitivity to DSB-inducing therapies highlighting its utility for studying DNA repair mechanisms and potential as an adjunct in cancer research
eMolecules 24484-98-8 | 2,3-Diamino-4-chloropyridine | Synthonix - Stock | MFCD13181777 | 143.570 | C5H6ClN3 | 95.000 | Nc1nccc(Cl)c1N | 1g | 525914236
2,3-Diamino-4-chloropyridine | Synthonix - Stock | 24484-98-8 | MFCD13181777 | 143.570 | C5H6ClN3 | 95.000 | Nc1nccc(Cl)c1N | 1g | 525914236
eMolecules 24484-98-8 | 2,3-Diamino-4-chloropyridine | Synthonix - Stock | MFCD13181777 | 143.570 | C5H6ClN3 | 95.000 | Nc1nccc(Cl)c1N | 5g | 525914237
2,3-Diamino-4-chloropyridine | Synthonix - Stock | 24484-98-8 | MFCD13181777 | 143.570 | C5H6ClN3 | 95.000 | Nc1nccc(Cl)c1N | 5g | 525914237
TARGETMOL CHEMICALS INC CE-224535 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CE-224535 (PF-04905428) is a selective antagonist of P2X7 receptor. CE-224535 can be used in disease-modifying antirheumatic studies. purity: 98%
eMolecules Matrix Scientific 2-(2-Propynyloxy)benzenecarboxylic acid 500mg 389719847 42654 95.000 55582-31-5 MFCD03001228 176.171 C10H8O3
Matrix Scientific 2-(2-Propynyloxy)benzenecarboxylic acid 500mg 389719847 42654 95.000 55582-31-5 MFCD03001228 176.171 C10H8O3
Apexbio Technology LLC 3'-O-Methyl-CTP 50ul (100 mM)
3p-O-Methyl-CTP is a modified nucleoside triphosphate It features a methyl group at the 3 -hydroxyl position of the ribose enabling enzymatic incorporation into nucleic acids and modulating physicochemical properties such as RNA stability and protein interactions 3p-O-Methyl-CTP exerts its biological activity by serving as a substrate for RNA synthesis introducing sugar modifications that impact RNA-protein recognition mechanisms and gene expression regulation Based on these characteristics 3p-O-Methyl-CTP holds research potential in molecular biology and epigenetics facilitating studies on RNA modifications nucleic acid modulation and the functional analysis of epigenetic processes
eMolecules 6164-79-0 | Methyl 2-Pyrazinecarboxylate | Accela ChemBio (ASD) | MFCD00014611 | 138.126 | C6H6N2O2 | 97.000 | COC(=O)c1cnccn1 | 10g | 591777677
Methyl 2-Pyrazinecarboxylate | Accela ChemBio (ASD) | 6164-79-0 | MFCD00014611 | 138.126 | C6H6N2O2 | 97.000 | COC(=O)c1cnccn1 | 10g | 591777677
eMolecules 98006-90-7 | 2-bromo-5-methylpyrazine | Pharmablock | MFCD08705754 | 173.013 | C5H5BrN2 | 97.000 | Cc1cnc(Br)cn1 | 2.5g | 686929424
2-bromo-5-methylpyrazine | Pharmablock | 98006-90-7 | MFCD08705754 | 173.013 | C5H5BrN2 | 97.000 | Cc1cnc(Br)cn1 | 2.5g | 686929424
eMolecules 5780-66-5 | Pyrazine-2-carbaldehyde | Combi-Blocks | MFCD02179278 | 108.100 | C5H4N2O | 98.000 | O=Cc1cnccn1 | 1g | 117563116
Pyrazine-2-carbaldehyde | Combi-Blocks | 5780-66-5 | MFCD02179278 | 108.100 | C5H4N2O | 98.000 | O=Cc1cnccn1 | 1g | 117563116
eMolecules 5780-66-5 | pyrazine-2-carbaldehyde | Pharmablock | MFCD02179278 | 108.100 | C5H4N2O | 97.000 | O=Cc1cnccn1 | 25mg | 586136505
pyrazine-2-carbaldehyde | Pharmablock | 5780-66-5 | MFCD02179278 | 108.100 | C5H4N2O | 97.000 | O=Cc1cnccn1 | 25mg | 586136505
eMolecules 6164-79-0 | Methyl 2-pyrazinecarboxylate | Synthonix - Stock | MFCD00014611 | 138.126 | C6H6N2O2 | 97.000 | COC(=O)c1cnccn1 | 25g | 525920637
Methyl 2-pyrazinecarboxylate | Synthonix - Stock | 6164-79-0 | MFCD00014611 | 138.126 | C6H6N2O2 | 97.000 | COC(=O)c1cnccn1 | 25g | 525920637