Pyrazines
TARGETMOL CHEMICALS INC GOSSYPOLONE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Gossypolone is is a proposed major metabolite of gossypol. Gossypolone reduces Notch/Wnt signaling and induces apoptosis. purity: 96%
eMolecules 1260663-68-0 | 3-Amino-5-chloropyrazine-2-carboxylic acid | ChemScene | MFCD18250527 | 173.560 | C5H4ClN3O2 | 95.000 | Nc1nc(Cl)cnc1C(O)=O | 5g | 582636618
3-Amino-5-chloropyrazine-2-carboxylic acid | ChemScene | 1260663-68-0 | MFCD18250527 | 173.560 | C5H4ClN3O2 | 95.000 | Nc1nc(Cl)cnc1C(O)=O | 5g | 582636618
eMolecules 5415-98-5 | 2-((Dimethylamino)methyl)acrylic acid | Ambeed | MFCD19656217 | 129.159 | C6H11NO2 | 95.000 | CN(C)CC(=C)C(O)=O | 1g | 589946283
2-((Dimethylamino)methyl)acrylic acid | Ambeed | 5415-98-5 | MFCD19656217 | 129.159 | C6H11NO2 | 95.000 | CN(C)CC(=C)C(O)=O | 1g | 589946283
![eMolecules 1380571-72-1 | 6-Oxa-1-azaspiro[3.3]heptane hemioxalate | ChemScene | MFCD22373634 | 288.300 | C12H20N2O6 | 97.000 | OC(=O)C(O)=O.C1CC2(COC2)N1.C1CC2(COC2)N1 | 1g | 572309274](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502695648.jpg-250.jpg)
eMolecules 1380571-72-1 | 6-Oxa-1-azaspiro[3.3]heptane hemioxalate | ChemScene | MFCD22373634 | 288.300 | C12H20N2O6 | 97.000 | OC(=O)C(O)=O.C1CC2(COC2)N1.C1CC2(COC2)N1 | 1g | 572309274
6-Oxa-1-azaspiro[3.3]heptane hemioxalate | ChemScene | 1380571-72-1 | MFCD22373634 | 288.300 | C12H20N2O6 | 97.000 | OC(=O)C(O)=O.C1CC2(COC2)N1.C1CC2(COC2)N1 | 1g | 572309274
Apexbio Technology LLC 2,4-Diamino-6-hydroxypyrimidine 56-06-4 10mM (in 1mL DMSO)
2 4-Diamino-6-hydroxypyrimidine (CAS 56-06-4) is a small molecule inhibitor targeting GTP cyclohydrolase I the rate-limiting enzyme in the de novo biosynthesis of tetrahydrobiopterin (BH4) By suppressing GTP cyclohydrolase I activity this compound reduces intracellular levels of BH4 consequently leading to decreased nitric oxide (NO) synthesis It is commonly utilized in studies investigating the roles of BH4 and NO in physiological and pathological contexts including research on neuronal signaling immune modulation and cardiovascular dysfunction
eMolecules 51673-83-7 | Tetrahydropyran-2-carboxylic acid | ChemScene | MFCD07779239 | 130.143 | C6H10O3 | 95.000 | OC(=O)C1CCCCO1 | 10g | 569147380
Tetrahydropyran-2-carboxylic acid | ChemScene | 51673-83-7 | MFCD07779239 | 130.143 | C6H10O3 | 95.000 | OC(=O)C1CCCCO1 | 10g | 569147380
eMolecules 118-90-1 | o-Toluic Acid | Accela ChemBio (ASD) | MFCD00002477 | 136.150 | C8H8O2 | 98.000 | Cc1ccccc1C(O)=O | 25g | 571781962
o-Toluic Acid | Accela ChemBio (ASD) | 118-90-1 | MFCD00002477 | 136.150 | C8H8O2 | 98.000 | Cc1ccccc1C(O)=O | 25g | 571781962
![eMolecules 4042-36-8 | D-Pyr-OH | Ambeed | MFCD00066212 | 129.115 | C5H7NO3 | 98.000 | OC(=O)[C@H]1CCC(=O)N1 | 100g | 552609318](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502695782.jpg-250.jpg)
eMolecules 4042-36-8 | D-Pyr-OH | Ambeed | MFCD00066212 | 129.115 | C5H7NO3 | 98.000 | OC(=O)[C@H]1CCC(=O)N1 | 100g | 552609318
D-Pyr-OH | Ambeed | 4042-36-8 | MFCD00066212 | 129.115 | C5H7NO3 | 98.000 | OC(=O)[C@H]1CCC(=O)N1 | 100g | 552609318
TARGETMOL CHEMICALS INC CILOMILAST 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Cilomilast (SB-207499) is a potent PDE4 inhibitor with IC50 of about 110 nM has anti-inflammatory activity and low central nervous system activity. Phase 3. purity: 99%
TARGETMOL CHEMICALS INC CCT129202 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. CCT129202 is an ATP-competitive pan-Aurora inhibitor for Aurora A Aurora B and Aurora C with IC50 of 0.042 uM 0.198 uM and 0.227 uM respectively. It is less potent to FGFR3 GSK3(beta) PDGFR(beta) etc. purity: 98%
TARGETMOL CHEMICALS INC SR15006 5MG
Also available in 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM). purity: 99%
TARGETMOL CHEMICALS INC ELOVL1-IN-2 5MG
Also available in 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. ELOVL1-IN-2 a compound known as an inhibitor of the elongation of very long chain fatty acid 1 (ELOVL1) enzyme exhibits a weak inhibitory effect on ELOVL1 (with an IC50 of 21 uM) and demonstrates moderate potency in a primary cellular assay conducted on HEK293 C26 cells (with an IC50 of 6.7 uM) [1]. purity: 99%
TARGETMOL CHEMICALS INC PBRM1-BD2-IN-5 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. PBRM1-BD2-IN-5 is a potent PBRM1 Bromodomain inhibitor with Kd values of 1.5 uM and 3.9 uM for PBRM1-BD2 and PBRM1-BD5 respectively and an IC50 value of 0.26 uM for PBRM1-BD2. PBRM1-BD2-IN-5 reduces the binding of full-length PBRM1 within the PBAF complex in cell lysates to acetylated histone peptide. PBRM1-BD2-IN-5 can be used to research anticancer. purity: 99%
TARGETMOL CHEMICALS INC GLASDEGIB 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Glasdegib (PF-04449913) (PF-04449913) is a potent and orally bioavailable Smoothened (Smo) inhibitor with IC50 of 5 nM. Phase 2. purity: 98%