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Aromatic organic heterocyclic compounds that consist of a six-membered ring with four carbon atoms and two nitrogen atoms at opposite positions of the ring, making this ring symmetrical.
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Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CU-115 is a selective and potent TLR8 antagonist with IC50 of 1.04 µM and =>50 µM for TLR8 and TLR7 respectively. CU-115 decreases production of TNF-(alpha) and IL-1(beta) activated by R-848 in THP-1 cells. purity: 100%
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