Pyridazines and derivatives
Luminol 98.0+%, TCI America™
CAS: 521-31-3 Molecular Formula: C8H7N3O2 Molecular Weight (g/mol): 177.163 MDL Number: MFCD00006890 InChI Key: HWYHZTIRURJOHG-UHFFFAOYSA-N Synonym: luminol,3-aminophthalhydrazide,3-aminophthalic hydrazide,5-amino-2,3-dihydro-1,4-phthalazinedione,1,4-phthalazinedione, 5-amino-2,3-dihydro,3-aminophthalic acid hydrazide,5-amino-1,2,3,4-tetrahydrophthalazine-1,4-dione,unii-5exp385q4f,ccris 5962,3-aminophthalylhydrazide PubChem CID: 10638 IUPAC Name: 5-amino-2,3-dihydrophthalazine-1,4-dione SMILES: C1=CC2=C(C(=C1)N)C(=O)NNC2=O
Amezinium Methyl Sulfate 98.0+%, TCI America™
CAS: 30578-37-1 Molecular Formula: C12H15N3O5S Molecular Weight (g/mol): 313.33 MDL Number: MFCD00865972 InChI Key: ZEASXVYVFFXULL-UHFFFAOYSA-N Synonym: 4-Amino-6-methoxy-1-phenylpyridazinium Methyl Sulfate PubChem CID: 71926 IUPAC Name: 4-amino-6-methoxy-1-phenyl-1λ⁵-pyridazin-1-ylium methyl sulfate SMILES: COS([O-])(=O)=O.COC1=CC(N)=CN=[N+]1C1=CC=CC=C1
4-Nitrophthalic Hydrazide 98.0+%, TCI America™
CAS: 3682-19-7 Molecular Formula: C8H5N3O4 Molecular Weight (g/mol): 207.15 MDL Number: MFCD00006891 InChI Key: XQFIOLKLHNOFCA-UHFFFAOYSA-N Synonym: 4-Nitrophthalhydrazide, 2,3-Dihydro-6-nitro-1,4-phthalazinedione PubChem CID: 3543259 IUPAC Name: 6-nitro-1,2,3,4-tetrahydrophthalazine-1,4-dione SMILES: [O-][N+](=O)C1=CC=C2C(=O)NNC(=O)C2=C1
6-Hydroxypyridazine-3-carboxylic Acid Monohydrate 98.0+%, TCI America™
CAS: 306934-80-5 Molecular Formula: C5H6N2O4 Molecular Weight (g/mol): 158.113 MDL Number: MFCD09064936 InChI Key: DZCBVXKRERSHAA-UHFFFAOYSA-N PubChem CID: 2774651 IUPAC Name: 6-oxo-1H-pyridazine-3-carboxylic acid;hydrate SMILES: C1=CC(=O)NN=C1C(=O)O.O
Isoluminol 98.0+%, TCI America™
CAS: 3682-14-2 Molecular Formula: C8H7N3O2 Molecular Weight (g/mol): 177.16 MDL Number: MFCD00010560 InChI Key: HUDPLKWXRLNSPC-UHFFFAOYSA-N Synonym: 4-aminophthalhydrazide,isoluminol,6-aminophthalazine-1,4-diol,chembl14882,1,4-phthalazinedione, 6-amino-2,3-dihydro,6-amino-2,3-dihydro-1,4-phthalazinedione,iso-luminol,1enu,4-aminophthaloylhydrazine,4-amino-phthalsaeure-hydrazid PubChem CID: 95014 IUPAC Name: 6-amino-1,2,3,4-tetrahydrophthalazine-1,4-dione SMILES: NC1=CC=C2C(=O)NNC(=O)C2=C1
1,4,5,6-Tetrahydro-6-oxopyridazine-3-carboxylic Acid 98.0+%, TCI America™
CAS: 27372-38-9 Molecular Formula: C5H6N2O3 Molecular Weight (g/mol): 142.114 MDL Number: MFCD00052030 InChI Key: VUADWGRLHPTYPI-UHFFFAOYSA-N Synonym: 6-oxo-1,4,5,6-tetrahydropyridazine-3-carboxylic acid,1,4,5,6-tetrahydro-6-oxopyridazine-3-carboxylic acid,unii-ot09ztp07e,ot09ztp07e,6-oxo-1,4,5,6-tetrahydro-pyridazine-3-carboxylic acid,3-pyridazinecarboxylic acid, 1,4,5,6-tetrahydro-6-oxo,1,4,5,6-tetrahydro-6-oxo-3-pyridazinecarboxylic acid,6-oxo-1,4,5,6-tetrahydropyridazin-3-carboxylic acid,6-oxo-1,4,5-trihydropyridazine-3-carboxylic acid,pubchem19274 PubChem CID: 99621 IUPAC Name: 6-oxo-4,5-dihydro-1H-pyridazine-3-carboxylic acid SMILES: C1CC(=O)NN=C1C(=O)O
Phthalic Hydrazide 98.0+%, TCI America™
CAS: 1445-69-8 Molecular Formula: C8H6N2O2 Molecular Weight (g/mol): 162.15 MDL Number: MFCD00006888 InChI Key: JNQUJPBFSQETPT-UHFFFAOYNA-N Synonym: 2,3-dihydro-1,4-phthalazinedione,phthalazine-1,4-diol,phtalylhydrazine,1,2,3,4-tetrahydrophthalazine-1,4-dione,1,4-phthalazinedione, 2,3-dihydro,1 2h-phthalazinone, 4-hydroxy,2,3-dihydro-phthalazine-1,4-dione,phthalhydrazine,phthalylhydrazine,phthaloylhydrazine PubChem CID: 219401 IUPAC Name: 1,4,4a,8a-tetrahydrophthalazine-1,4-dione SMILES: O=C1N=NC(=O)C2C=CC=CC12
Sigma Aldrich Fine Chemicals Biosciences Luminol >=97% (HPLC) | 521-31-3 | MFCD00006890 | 25G
Luminol >=97% (HPLC) | Purity: >=97% (HPLC) | Mol Wt: 177.16 | 521-31-3 | MFCD00006890 | 25G
Sigma Aldrich Fine Chemicals Biosciences SR-95531 >=98% (HPLC), powder | 104104-50-9 | MFCD00055135 | 10MG
SR-95531 >=98% (HPLC), powder | Purity: >=98% (HPLC) | Mol Wt: 368.23 | 104104-50-9 | MFCD00055135 | 10MG
Sigma Aldrich Fine Chemicals Biosciences Luminol | 521-31-3 | MFCD00006890 | 5g
Luminol | Purity: 97% | Mol Wt: 177.16521-31-3 | MFCD00006890 | 5g
Sigma Aldrich Fine Chemicals Biosciences 4-Aminophthalhydrazide | 3682-14-2 | MFCD00010560 | 1G
4-Aminophthalhydrazide | Purity: >=98% (HPLC) | Mol Wt: 177.16 | 3682-14-2 | MFCD00010560 | 1G
Medchemexpress LLC 3-pyridin-3-ylpropyl (2S)-1-(3,3-dimethyl-2-oxopentanoyl)pyrrolidine-2-carboxylate | 186452-09-5 | MFCD00953146 | 99.8% | 360.45 g/mol | C20H28N2O4 | 10MM 1ML
GPI-1046 is a non-immunosuppressive immunophilin ligand used in preclinical research for neuroprotection and modulation of glutamate transport. It is supplied in solution and solid formats for flexible use in in vitro and in vivo studies, and is intended for research use only.
- Non-immunosuppressive immunophilin ligand with reported neuroprotective activity.
- Modulates glutamate transporter 1 (GLT1) in preclinical models.
- Available as a 10 mM solution in DMSO and as solid mg quantities for experimental flexibility.
- High purity (≈99.8%).
- Molecular weight 360.45 g/mol; formula C20H28N2O4 for reference.
- Recommended storage: protect from light; in solvent store at -80°C for long-term preservation.
Medchemexpress LLC Phthalazine | 253-52-1 | 130.15 | 25 G
Phthalazine (Standard) is the analytical standard for Phthalazine, designed for research and analytical applications. It functions as a substrate for human aldehyde oxidase 1, which can lead to the generation of Reactive Oxygen Species (ROS) and subsequent inactivation of the enzyme. This product is an organic heterocyclic compound containing nitrogen. It has demonstrated antitumor activity in various cancers, including blood cancer, breast cancer, colon cancer, lung cancer, and renal cancer.
- Analytical standard for various assays.
- Utilized in qualitative, quantitative, and methodological research experiments, including techniques such as HPLC, GC, and MS.
- Exhibits antitumor activity against blood cancer, breast cancer, colon cancer, lung cancer, and renal cancer.
Medchemexpress LLC Phthalazine | 253-52-1 | 130.15 | 10 G
Phthalazine is a nitrogen-containing organic heterocyclic compound that serves as a substrate for human aldehyde oxidase 1, which leads to the production of reactive oxygen species (ROS) and subsequent enzyme inactivation. It has demonstrated antitumor activity in various cancers, including blood cancer, breast cancer, colon cancer, lung cancer, and renal cancer.
- Substrate for human aldehyde oxidase 1
- Can lead to ROS production and enzyme inactivation
- Nitrogen-containing organic heterocyclic compound
- Exhibits antitumor activity in multiple cancer types
- Store powder at -20°C for 3 years or 4°C for 2 years
- Store in solvent at -80°C for 6 months or -20°C for 1 month
- Appears as a yellow to brown solid
Medchemexpress LLC Zardaverine | 101975-10-4 | C12H10F2N2O3 | 1 ML
Zardaverine is an orally active and selective PDE3/4 inhibitor with potent bronchodilator activity. It selectively inhibits the proliferation of HCC cells, inducing apoptosis and cell cycle arrest (G0/G1 phase). Zardaverine demonstrates good antitumor potential and is effective in bronchial relaxation and reducing inflammation in asthma.
- Targets phosphodiesterase (PDE) and apoptosis
- Pathway: Metabolic enzyme/protease and apoptosis
- Storage for powder: -20°C for 3 years, 4°C for 2 years
- Storage in solvent: -80°C for 2 years, -20°C for 1 year
- Soluble in DMSO (25 mg/mL)
- Soluble in 10% DMSO, 40% PEG300, 5% Tween-80, 45% saline (≥ 2.08 mg/mL)
- Soluble in 10% DMSO, 90% corn oil (≥ 2.08 mg/mL)
- IC₅₀ target: PDE3, PDE4
- 1
- 2