Pyridines and derivatives

Aromatic organic compounds consist of an aromatic six-membered ring containing one nitrogen atom and five carbon atoms; includes compounds derived from pyridines.

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4,051 – 4,065 of 158,737 results

4,051

Medchemexpress LLC MYF-03-176 | 2857937-59-6 | 99.7% | 410.37 | 5 MG

MYF-03-176 | 2857937-59-6 | 99.7% | 410.37 | 5 MG

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4,052

Medchemexpress LLC NLRP3-IN-11 | 2769040-91-5 | 344.8 | 100 MG

NLRP3-IN-11 is a NLR family pyrin domain containing 3 (NLRP3) proteins inhibitor with an IC50 value of <0.3 μM for NLRP3. It is used in the research of inflammatory and degenerative diseases including NASH, atherosclerosis, other cardiovascular diseases, Alzheimer's disease, Parkinson's disease, diabetes, and gout. This product should be stored at 4°C, protected from light. In solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light.

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4,053

Medchemexpress LLC (S)-Minzasolmin | 1802518-91-7 | 99.4% | 425.59 g/mol | C23H31N5OS | 5 MG

(S)-Minzasolmin is the S-enantiomer of minzasolmin, a small-molecule inhibitor of α-synuclein oligomerization supplied for research use. It is intended for preclinical biochemical and pharmacological studies investigating synuclein aggregation and related disease models, and is provided as a characterized, high-purity reagent.

High purity suitable for analytical and biological assays.
Chiral S-enantiomer for stereospecific activity studies.
Active in inhibiting α-synuclein oligomerization in vitro and in vivo models.
Provided in small milligram quantities for research workflows.
Characterized by formula C23H31N5OS and molecular weight 425.59 g/mol.

Pricing & Availability

4,054

Medchemexpress LLC 5-Bromo-2-nitropyridine | 39856-50-3 | 99.8% | C5H3BrN2O2 | 50 G

5-Bromo-2-nitropyridine is a biochemical reagent utilized as a biological material or organic compound for life science related research. It is presented as a solid with a white to light yellow color, intended exclusively for research applications.

Functions as a biological material or organic compound
Applicable for life science research
Solid physical form
Features a white to light yellow appearance

Pricing & Availability

4,055

Medchemexpress LLC Valrocemide | 92262-58-3 | MFCD00870963 | 99.4% | 200.28 g/mol | C10H20N2O2 | 25 MG

Valrocemide is a small-molecule anticonvulsant research compound described as a promising antiepileptic candidate with broad-spectrum anticonvulsant activity. It is supplied as a white to off-white solid for laboratory research use only and is characterized by a reported purity of 99.42%.

Broad-spectrum anticonvulsant activity reported in preclinical studies.
High reported purity (99.42%).
White to off-white solid suitable for analytical and in vivo research.
Stable under recommended storage: powder -20°C (3 years) or 4°C (2 years).
Solvent stability for prepared solutions: -80°C (2 years) or -20°C (1 year).
Available in small research quantities, useful for assay development and pilot studies.

Pricing & Availability

4,056

Medchemexpress LLC BAY-728 | C24H28F3N5O2S | 1 ML

BAY-728 serves as a negative control for BAY-805, which is described as a potent and selective inhibitor of USP21. This product is intended for research use only and is not sold to patients. It appears as a white to off-white solid with a molecular weight of 507.57.

Used as a negative control for BAY-805
Potent and selective inhibitor of USP21
Intended for research use only
Appears as a white to off-white solid
Suitable for laboratory chemicals and manufacturing substances

Pricing & Availability

4,057

Medchemexpress LLC SHP099 monohydrochloride | 2200214-93-1 | 99.9% | 388.72 | C16H20Cl3N5 | 500 MG

SHP099 monohydrochloride is the hydrochloride salt of a potent, selective, allosteric SHP2 inhibitor used to probe SHP2-dependent signaling in cellular and preclinical studies. It stabilizes SHP2 in an autoinhibited conformation, suppresses RAS-ERK signaling, and has demonstrated efficacy in models driven by receptor tyrosine kinases.

Potent SHP2 inhibition (IC50 ≈ 70 nM).
High purity suitable for biological studies.
Orally bioavailable in preclinical models.
Useful for in vitro and in vivo signaling pathway studies.
Available in multiple pack sizes for flexible experimental needs.

Pricing & Availability

4,058

Medchemexpress LLC CWI1-2 | 2408590-36-1 | C22H17Cl3N6O3 | 5 MG

CWI1-2 is an IGF2BP2 inhibitor that binds IGF2BP2 and inhibits its interaction with m6A-modified target transcripts. It induces apoptosis and differentiation, and demonstrates promising anti-leukemic effects.

Binds to IGF2BP2
Inhibits interaction with m6A-modified target transcripts
Induces apoptosis and differentiation
Shows promising anti-leukemic effects
Exhibits antiproliferative activity with an IC50 of 200 nM against human THP-1 cells
Reduces glutamine uptake and impairs mitochondrial function in AML cells
Significantly inhibits the colony-forming ability of leukemic mouse blasts
Greatly impairs the self-renewal of leukemic stem/initiating cells

Pricing & Availability

4,059

Medchemexpress LLC 5-(tetradecyloxy)-2-furoic acid | 54857-86-2 | MFCD01726059 | 99.9% | 324.45 g·mol⁻¹ | C19H32O4 | 25 MG

TOFA (5-(tetradecyloxy)-2-furoic acid) is an allosteric inhibitor of acetyl-CoA carboxylase used as a research reagent to block fatty acid synthesis in biochemical and cell biology studies. It is cell-permeable and commonly applied in vitro to investigate lipid metabolism and related signaling pathways. For research use only; not for human or veterinary applications.

Allosteric inhibitor of acetyl-CoA carboxylase.
Reduces cellular fatty acid synthesis.
Cell-permeable small molecule suitable for in vitro assays.
Supplied in laboratory-ready quantities for experimental use.
High purity for reproducible biochemical results.

Pricing & Availability

4,060

Medchemexpress LLC N-(4-(6,7-dimethoxyquinolin-4-yl)oxy-3-fluorophenyl)-3-(4-fluorophenyl)pyrimidine-5-carboxamide | 1437321-24-8 | 99.6% | 588.56 | C31H26F2N4O6 | 1 G

CEP-40783 is a potent, selective, orally available small-molecule inhibitor of the receptor tyrosine kinases AXL and c-Met. It exhibits low-nanomolar biochemical potency, enhanced cellular activity, high kinome selectivity, and has shown dose-dependent target inhibition and antitumor efficacy in preclinical in vivo models.

Potent biochemical activity: AXL IC50 of 7 nM and c-Met IC50 of 12 nM.
Enhanced cellular potency in model cell lines (AXL-transfected 293GT IC50 ≈ 0.26 nM; GTL-16 c-Met IC50 ≈ 6 nM).
High kinome selectivity with S90 = 0.04 against 298 kinases.
Demonstrated dose- and time-dependent target inhibition and tumor regressions in xenograft studies.
Supplied for research use with high reported purity.

Pricing & Availability

4,061

Apexbio Technology LLC Ondansetron HCl 99614-01-4 10mg

Ondansetron HCl (CAS 99614-01-4) is a selective antagonist of the serotonin 5-hydroxytryptamine 3 (5-HT3) receptor By inhibiting the activation of these ligand-gated ion channels it modulates serotonergic signaling pathways implicated in emesis and other neuropharmacological processes Ondansetron HCl is widely utilized in biomedical research to investigate serotonergic modulation in gastrointestinal central nervous system and chemotherapy-induced emesis models Its specific inhibition of 5-HT3 receptors makes it a valuable tool for delineating the physiological and pharmacological roles of this receptor subtype across various experimental paradigms

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4,062

Apexbio Technology LLC NS3694 426834-38-0 50mg

NS3694 (CAS 426834-38-0) is a diarylurea small molecule that functions as an inhibitor of apoptosome formation and caspase activation In HeLa cell cytosolic extracts NS3694 demonstrates an IC50 of approximately 50 M for the inhibition of cytochrome c-induced caspase activity It blocks the association of caspase 9 and Apaf-1 thereby preventing assembly of the functional 700-kDa apoptosome complex without directly inhibiting recombinant caspase 9 or caspase 3 NS3694 does not affect TNF-induced or FasL-induced caspase activation in other contexts This compound serves as a research tool for investigating intrinsic apoptotic signaling and apoptosome-mediated caspase activation in vitro

Pricing & Availability

4,063

Apexbio Technology LLC SB743921 940929-33-9 10mg

SB743921 (CAS 940929-33-9) is a potent and selective inhibitor of kinesin spindle protein (KSP) exhibiting a Ki of 0 1 nM for human KSP and 0 12 nM for mouse KSP with negligible affinity for other kinesins By targeting KSP SB743921 disrupts mitotic spindle formation leading to cell cycle arrest and apoptosis In cellular assays SB743921 demonstrates strong antiproliferative activity against SKOV3 Colo205 MV522 and MX1 cell lines with IC50 values ranging from 0 02 to 1 7 nM Additionally it shows efficacy in multiple human tumor xenograft models and in a murine P388 lymphocytic leukemia model SB743921 is utilized in oncology research for mechanistic studies and therapeutic evaluation of mitotic inhibition

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4,064

Medchemexpress LLC MEDCHEMEXPRESS LLC

5000702752 DHQZ 36 50MG

Pricing & Availability

4,065

Medchemexpress LLC Toxoflavin | 84-82-2 | MFCD00459812 | 99.9% | 193.16 g/mol | C7H7N5O2 | 100 MG

Toxoflavin is a small-molecule research compound that modulates signaling and epigenetic targets. It acts as an antagonist of the transcription factor 4 (TCF4)/β-catenin complex and inhibits the histone demethylase KDM4A; it has reported antitumor and antibiotic activities and is supplied for research use only.

Antagonist of TCF4/β-catenin signaling.
Inhibitor of histone demethylase KDM4A.
Reported antitumor and antibiotic activity in research studies.
High chemical purity suitable for analytical and biological assays.
Soluble in DMSO and water; warming or sonication may aid dissolution.

Pricing & Availability

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Pyridines and derivatives

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Medchemexpress LLC MYF-03-176 | 2857937-59-6 | 99.7% | 410.37 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC NLRP3-IN-11 | 2769040-91-5 | 344.8 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (S)-Minzasolmin | 1802518-91-7 | 99.4% | 425.59 g/mol | C23H31N5OS | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 5-Bromo-2-nitropyridine | 39856-50-3 | 99.8% | C5H3BrN2O2 | 50 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Valrocemide | 92262-58-3 | MFCD00870963 | 99.4% | 200.28 g/mol | C10H20N2O2 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC BAY-728 | C24H28F3N5O2S | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SHP099 monohydrochloride | 2200214-93-1 | 99.9% | 388.72 | C16H20Cl3N5 | 500 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC CWI1-2 | 2408590-36-1 | C22H17Cl3N6O3 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 5-(tetradecyloxy)-2-furoic acid | 54857-86-2 | MFCD01726059 | 99.9% | 324.45 g·mol⁻¹ | C19H32O4 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC N-(4-(6,7-dimethoxyquinolin-4-yl)oxy-3-fluorophenyl)-3-(4-fluorophenyl)pyrimidine-5-carboxamide | 1437321-24-8 | 99.6% | 588.56 | C31H26F2N4O6 | 1 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC Ondansetron HCl 99614-01-4 10mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC NS3694 426834-38-0 50mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC SB743921 940929-33-9 10mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC MEDCHEMEXPRESS LLC Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Toxoflavin | 84-82-2 | MFCD00459812 | 99.9% | 193.16 g/mol | C7H7N5O2 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More