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Filtered Search Results
Medchemexpress LLC HY-10961 10mg Medchemexpress, Momelotinib CAS:1056634-68-4 Purity:>98%
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Medchemexpress, HY-10961 10mg Momelotinib CAS:1056634-68-4 Momelotinib (CYT387) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50a of 11 nM and 18 nM,respectively. CYT387 shows much less activity against JAK3. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-10182 100mg , CHIR-99021 CT99021 CAS:252917-06-9 Purity:98%
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Medchemexpress, HY-10182 100mg CHIR-99021 CT99021 CAS:252917-06-9 Formula:C22H18Cl2N8 IC50: 10 nM/6.7 nM (GSK-3α/β) Purity:98% CHIR-99021 is a GSK-3α/β inhibitor with IC 50 of 10 nM/6.7 nM; > 500-fold selectivity for GSK-3 versus its closest homologs CDC2 and ERK2, as well as other protein kinases. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Apexbio Technology LLC BAY 61-3606 732983-37-8 5mg
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BAY 61-3606 (CAS 732983-37-8) is a selective orally bioavailable inhibitor of spleen tyrosine kinase (SYK) displaying an IC50 of 10 nM and a Ki of 7 5 nM for SYK by competitively binding ATP This compound shows minimal activity against other tyrosine kinases such as Src Fyn Lyn Btk and Itk at concentrations up to 4 7 M BAY 61-3606 suppresses Fc RI-mediated degranulation and mediator release in mast cells and basophils as well as Fc R-driven responses in macrophages and neutrophils In preclinical models BAY 61-3606 attenuates inflammatory cell functions and reduces allergic and asthmatic responses supporting its utility in investigating SYK-mediated signaling and inflammation
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Selleck Chemical LLC WYE-125132 (WYE-132) S2661-5mg
WYE-125132 (WYE-132) is a highly potent ATP-competitive mTOR inhibitor with IC50 of 0 19 nM highly selective for mTOR versus PI3Ks or PI3K-related kinases hSMG1 and ATR
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Medchemexpress LLC HY-111109 5mg Medchemexpress, EZM 2302 CAS:1628830-21-6 Purity:>98%
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Medchemexpress, HY-111109 5mg EZM 2302 CAS:1628830-21-6 EZM 2302 is an inhibitor of coactivator-associated arginine methyltransferase 1 (CARM1) with an IC50 of 6 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules Medchem Express / TH287 / 5mg / 446267994 / HY-16965 / / 1609960-30-6 / MFCD29035111 / 269.130 / C11H10Cl2N4
Medchem Express / TH287 / 5mg / 446267994 / HY-16965 / / 1609960-30-6 / MFCD29035111 / 269.130 / C11H10Cl2N4
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eMolecules Pharmablock / 5-fluoro-2-methyl-pyrimidine / 25mg / 788564172 / PBU2799 / 0.000 / 54376-50-0 / MFCD16611294 / 112.107 / C5H5FN2
Pharmablock / 5-fluoro-2-methyl-pyrimidine / 25mg / 788564172 / PBU2799 / 0.000 / 54376-50-0 / MFCD16611294 / 112.107 / C5H5FN2
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Medchemexpress LLC HY-10115A 100mg , PI-103 (Hydrochloride) CAS:371935-79-4 Purity:98%
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Medchemexpress, HY-10115A 100mg PI-103 (Hydrochloride) CAS:371935-79-4 Formula:C19H17ClN4O3 IC50: 8 nM (p110α), 88 nM (p110β), 48 nM (p110δ), 150 nM (p110γ), 2 nM (DNA-PK), 20 nM (mTORC1), 83 nM (mTORC2), 26 nM (PI3KC2β), 850 nM (ATR), 920 nM (ATM), ~1 μM (PI3KC2α), 2.3 μM (hsVPS34), ~50 μM (PI4KIIIβ) Purity:98% PI-103 Hydrochloride is a potent PI3K and mTOR inhibitor with IC 50 s of 8 nM, 88 nM, 48 nM, 150 nM, 20 nM, and 83 nM for p110α , p110β , p110δ , p110γ , mTORC1 , and mTORC2 . PI-103 also inhibits DNA-PK with an IC50 of 2 nM. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC MG-2119 | 1065500-40-4 | 99.68% | 487.55 | 50 MG
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MG-2119 is a potent monomeric tau and α-syn aggregation inhibitor, investigated as a potential agent for neurological disorders research. For optimal stability, store this product at 4°C, sealed, away from moisture and light. In solvent, store at -80°C for up to 6 months or -20°C for 1 month under similar sealed conditions.
- Potent monomeric tau and α-syn aggregation inhibitor
- Potential agent for neurological disorders research
- Store at 4°C sealed, away from moisture and light
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Medchemexpress LLC Phenyl 6-[[3-methoxy-2-[4-(CF3)phenyl]benzoyl]amino]-3,4-dihydro-1H-isoquinoline-2-carboxylate | 913541-47-6 | MFCD28502203 | ≥98.0% | 546.5 g·mol⁻¹ | C31H25F3N2O4 | 100 MG
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SLX-4090 is a small-molecule, orally active, enterocytic-specific microsomal triglyceride transfer protein (MTP) inhibitor with a reported IC50 of ~8.0 nM. It is used in preclinical research to investigate intestinal lipid absorption and dyslipidemia and is characterized in peer-reviewed literature.
- Potent MTP inhibition with low-nanomolar IC50.
- Enterocyte-selective activity targeting intestinal lipid handling.
- Suitable for preclinical and mechanistic studies of dyslipidemia.
- High chemical purity for reproducible experimental results.
- Available as solid and solution formulations for flexibility in assays.
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eMolecules TERT-BUTYL 3-BROMO-2-FORMYL-1H-INDOLE-1-CARBOXYLATE | 1346156-91-9 | MFCD24471460 | 1g
AstaTech | TERT-BUTYL 3-BROMO-2-FORMYL-1H-INDOLE-1-CARBOXYLATE | 1g | 402181208 | F30755 | 95.000 | 1346156-91-9 | MFCD24471460 | 324.174 | C14H14BrNO3
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Medchemexpress LLC Phenyl 6-(3-methoxy-2-(4-(trifluoromethyl)phenyl)benzoylamino)-3,4-dihydroisoquinoline-2-carboxylate | 913541-47-6 | MFCD28502203 | 99.0% | 546.54 | C31H25F3N2O4 | 50 MG
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SLX-4090 is an orally active, enterocytic-specific microsomal triglyceride transfer protein (MTP) inhibitor (IC50 8.0 nM) used as a research reagent in dyslipidemia and lipid metabolism studies. It is supplied as a purified solid and is available in solution formats suitable for in vitro and in vivo assays.
- High potency MTP inhibition (IC50 ~8.0 nM).
- Enterocytic-specific activity useful for targeted lipid studies.
- High purity (about 98.97%) for reproducible results.
- Available as solid and DMSO solution formats for assay flexibility.
- Suitable for dyslipidemia and lipid metabolism research models.
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eMolecules 2-(2-Methylphenyl)pyrimidine-5-carbaldehyde | 876710-73-5 | 1G
Chem-Impex | 2-(2-Methylphenyl)pyrimidine-5-carbaldehyde | 1G | 876710-73-5 | MFCD08272865 | MW:195.22
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eMolecules 1-(2,5-Dibromophenyl)thiourea | 854890-84-9 | MFCD14673413 | 1g
Combi-Blocks | 1-(2,5-Dibromophenyl)thiourea | 1g | 117531798 | HC-3368 | 98.000 | 854890-84-9 | MFCD14673413 | 310.010 | C7H6Br2N2S
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eMolecules 2-Chloro-4,6-diphenylpyrimidine | 2915-16-4 | 1G | Purity: 95%
Matrix Scientific | 2-Chloro-4,6-diphenylpyrimidine | 1G | 2915-16-4 | MFCD00030776
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