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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000734650 4-PYRIMIDIN-5-YLBE 250MG
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Medchemexpress LLC SSD114 hydrochloride | 2319790-02-6 | MFCD31619246 | 99.1% | 387.83 | C18H21ClF3N3O | 25 MG
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SSD114 hydrochloride is a small-molecule positive allosteric modulator of the GABAB receptor intended for in vitro and in vivo research use only.
- Acts as a GABAB receptor positive allosteric modulator for pharmacological studies.
- High purity suitable for research applications.
- Solid, white to off-white appearance for ease of handling.
- Available in multiple small-scale quantities for experimental flexibility.
- Stable under recommended storage conditions to preserve compound integrity.
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Medchemexpress LLC PKI-166 10mg | 187724-61-4 | 330.38 | C20H18N4O | 10 MG
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PKI-166 is a potent, selective, and orally bioavailable epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor with a reported IC50 of 0.7 nM. It is provided for research use only and has molecular formula C20H18N4O and high purity by HPLC.
- Potent EGFR kinase inhibition (IC50 ≈ 0.7 nM).
- High chemical purity (≥98% by HPLC).
- Suitable for in vitro and in vivo research applications.
- Orally bioavailable in preclinical studies.
- Well-characterized molecular properties for experimental reproducibility.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000771515 5-PYRIMIDIN-5-YLIS 100MG
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Apexbio Technology LLC TELOTRISTAT 5MG
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TELOTRISTAT 5MG APEXBIO TECHNOLOGIES
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Medchemexpress LLC N-[4-[6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl]oxy-1,3-benzothiazol-2-yl]acetamide | 659730-32-2 | MFCD14584859 | 99.2% | 430.4 g·mol⁻¹ | C20H13F3N4O2S | 100 MG
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AMG 517 is a small-molecule antagonist of the TRPV1 (vanilloid) ion channel used to probe TRPV1-mediated signaling and pharmacology. It exhibits sub-nanomolar inhibitory potency and is supplied as a research-grade chemical with batch-specific quality documentation.
- Potent TRPV1 antagonist with reported IC50 in the sub-nanomolar range.
- Molecular formula C20H13F3N4O2S and molecular weight 430.4 g·mol⁻¹.
- High purity (≈99.2% by HPLC) suitable for biochemical assays.
- Available in solid and solution formats for assay flexibility.
- Used for in vitro and in vivo pharmacology and target validation.
- Provided with batch-specific certificate of analysis for QC.
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Medchemexpress LLC HY-10182 100mg , CHIR-99021 CT99021 CAS:252917-06-9 Purity:98%
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Medchemexpress, HY-10182 100mg CHIR-99021 CT99021 CAS:252917-06-9 Formula:C22H18Cl2N8 IC50: 10 nM/6.7 nM (GSK-3α/β) Purity:98% CHIR-99021 is a GSK-3α/β inhibitor with IC 50 of 10 nM/6.7 nM; > 500-fold selectivity for GSK-3 versus its closest homologs CDC2 and ERK2, as well as other protein kinases. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Apexbio Technology LLC BAY 61-3606 732983-37-8 5mg
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BAY 61-3606 (CAS 732983-37-8) is a selective orally bioavailable inhibitor of spleen tyrosine kinase (SYK) displaying an IC50 of 10 nM and a Ki of 7 5 nM for SYK by competitively binding ATP This compound shows minimal activity against other tyrosine kinases such as Src Fyn Lyn Btk and Itk at concentrations up to 4 7 M BAY 61-3606 suppresses Fc RI-mediated degranulation and mediator release in mast cells and basophils as well as Fc R-driven responses in macrophages and neutrophils In preclinical models BAY 61-3606 attenuates inflammatory cell functions and reduces allergic and asthmatic responses supporting its utility in investigating SYK-mediated signaling and inflammation
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eMolecules 1346156-91-9 | TERT-BUTYL 3-BROMO-2-FORMYL-1H-INDOLE-1-CARBOXYLATE | MFCD24471460 | 1g
ChemScene | (3-Iodo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-4-yl)methanol | 100mg | 572167053 | CS-0017743 | 1627924-18-8 | MFCD29918655 | 308.119 | C9H13IN2O2
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Apexbio Technology LLC PKI-402 5MG
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PKI-402 5MG APEXBIO TECHNOLOGIES
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Medchemexpress LLC Phenyl 6-(3-methoxy-2-(4-(trifluoromethyl)phenyl)benzoylamino)-3,4-dihydroisoquinoline-2-carboxylate | 913541-47-6 | MFCD28502203 | 99.0% | 546.54 | C31H25F3N2O4 | 50 MG
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SLX-4090 is an orally active, enterocytic-specific microsomal triglyceride transfer protein (MTP) inhibitor (IC50 8.0 nM) used as a research reagent in dyslipidemia and lipid metabolism studies. It is supplied as a purified solid and is available in solution formats suitable for in vitro and in vivo assays.
- High potency MTP inhibition (IC50 ~8.0 nM).
- Enterocytic-specific activity useful for targeted lipid studies.
- High purity (about 98.97%) for reproducible results.
- Available as solid and DMSO solution formats for assay flexibility.
- Suitable for dyslipidemia and lipid metabolism research models.
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eMolecules 50739-76-9 | (2-Amino-3,5-dibromophenyl)methanol | Combi-Blocks | MFCD06202693 | 280.947 | C7H7Br2NO | 95.000 | Nc1c(Br)cc(Br)cc1CO | 1g | 439374801
(2-Amino-3,5-dibromophenyl)methanol | Combi-Blocks | 50739-76-9 | MFCD06202693 | 280.947 | C7H7Br2NO | 95.000 | Nc1c(Br)cc(Br)cc1CO | 1g | 439374801
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Medchemexpress LLC Phenyl 6-[[3-methoxy-2-[4-(CF3)phenyl]benzoyl]amino]-3,4-dihydro-1H-isoquinoline-2-carboxylate | 913541-47-6 | MFCD28502203 | ≥98.0% | 546.5 g·mol⁻¹ | C31H25F3N2O4 | 100 MG
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SLX-4090 is a small-molecule, orally active, enterocytic-specific microsomal triglyceride transfer protein (MTP) inhibitor with a reported IC50 of ~8.0 nM. It is used in preclinical research to investigate intestinal lipid absorption and dyslipidemia and is characterized in peer-reviewed literature.
- Potent MTP inhibition with low-nanomolar IC50.
- Enterocyte-selective activity targeting intestinal lipid handling.
- Suitable for preclinical and mechanistic studies of dyslipidemia.
- High chemical purity for reproducible experimental results.
- Available as solid and solution formulations for flexibility in assays.
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Medchemexpress LLC Pi-103 10Mm/1Ml In Dmso | HY-10115
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Pi-103 10Mm/1Ml In Dmso
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000771222 5-PYRIMIDIN-5-YLIS 250MG
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