Pyrimidines And Derivatives
- (4)
- (2)
- (372)
- (11)
- (1)
- (1)
- (32)
- (8)
- (70)
- (1)
- (25)
- (2)
- (2)
- (14)
- (190)
- (4)
- (2)
- (7)
- (20)
- (1)
- (69)
- (1)
- (278)
- (11)
- (4)
- (11)
- (32)
- (2)
- (7)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (21)
- (1)
- (23)
- (7)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (12)
- (3)
- (4)
- (4)
- (4)
- (1)
- (4)
- (7)
- (4)
- (13)
- (1)
- (13)
- (2)
- (1)
- (3)
- (2)
- (1)
- (1)
- (4)
- (7)
- (10)
- (3)
- (17)
- (2)
- (1)
- (2)
- (2)
- (4)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (1)
- (1)
- (3)
- (5)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (4)
- (1)
- (8)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (4)
- (2)
- (1)
- (3)
- (1)
- (4)
- (1)
- (3)
- (1)
- (2)
- (4)
- (2)
- (1)
- (9)
- (1)
- (1)
- (1)
- (2)
- (6)
- (2)
- (1)
- (17)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (7)
- (1)
- (1)
- (2)
- (4)
- (4)
- (3)
- (1)
- (5)
- (3)
- (1)
- (2)
- (1)
- (1)
- (3)
- (3)
- (4)
- (2)
- (1)
- (8)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (4)
- (1)
- (2)
- (1)
- (5)
- (1)
- (6)
- (2)
- (1)
- (3)
- (9)
- (2)
- (2)
- (2)
- (3)
- (2)
- (2)
- (4)
- (2)
- (1)
- (5)
- (11)
- (6)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (7)
- (2)
- (2)
- (1)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (4)
- (1)
- (1)
- (4)
- (9)
- (3)
- (8)
- (1)
- (4)
- (1)
- (1)
- (1)
- (3)
- (1)
- (1)
- (3)
- (1)
- (2)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (4)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (2)
- (3)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (4)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (3)
- (1)
- (3)
- (1)
- (6)
- (1)
- (2)
- (1)
- (1)
- (1)
- (3)
- (3)
- (1)
- (2)
- (1)
- (2)
- (3)
- (1)
- (1)
- (3)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (7)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (3)
- (3)
- (2)
- (2)
- (1)
- (5)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (8)
- (1)
- (1)
- (1)
- (1)
- (1)
- (6)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (3)
- (4)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (4)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (5)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (6)
- (2)
- (4)
- (1)
- (3)
- (1)
- (3)
- (2)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (7)
- (3)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (4)
- (1)
- (1)
- (1)
- (5)
- (2)
- (3)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (3)
- (16)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (5)
- (1)
- (1)
- (4)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (1)
- (1)
- (15)
- (1)
- (1)
- (1)
- (14)
- (14)
- (1)
- (1)
- (3)
- (1)
- (4)
- (1)
- (1)
- (3)
- (2)
- (1)
- (1)
- (1)
- (1)
- (4)
- (4)
- (1)
- (2)
- (1)
- (3)
- (2)
- (2)
- (1)
- (4)
- (7)
- (3)
- (5)
- (1)
- (3)
- (1)
- (1)
- (26)
- (3)
- (66)
- (3)
- (34)
- (18)
- (3)
- (17)
- (71)
- (4)
- (27)
- (5)
- (1)
- (6)
- (1)
- (1)
- (2)
- (10)
- (1)
- (2)
- (1)
- (1)
- (3)
- (1)
- (4)
- (2)
- (6)
- (6)
- (59)
- (29)
- (214)
- (25)
- (161)
- (1)
- (3)
- (66)
- (18)
- (2)
- (11)
- (5)
- (340)
- (1)
- (24)
- (2)
- (3)
- (2)
- (3)
- (3)
- (5)
- (2)
- (1)
- (2)
- (10)
- (75)
- (55)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (3)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (3)
- (2)
- (2)
- (4)
- (1)
- (4)
- (1)
- (2)
- (4)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (3)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
Filtered Search Results
Apexbio Technology LLC Nilotinib monohydrochloride monohydrate 923288-90-8 250mg
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Nilotinib monohydrochloride monohydrate (CAS 923288-90-8) is a selective small molecule inhibitor targeting the BCR-ABL tyrosine kinase By binding to the ATP-binding site of BCR-ABL nilotinib effectively suppresses kinase activity impeding downstream signaling involved in cell proliferation It demonstrates potent inhibitory activity with an IC50 below 30 nM Nilotinib is widely utilized in biomedical research to investigate BCR-ABL-mediated cellular mechanisms and to model therapeutic interventions in chronic myelogenous leukemia and related malignancies
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Aobchem AOBCHEM
5000866313 3 5-DIISOPROPYLBENZOIC ACID 50
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Aobchem AOBCHEM
5000863851 ETHYL 2- 1-HYDROXYCYCLOPENTYL
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Ambeed AMBEED
5000869677 33-DISULFANEDIYLDIPROPANEN 1GR
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
eMolecules 1158207-20-5 | Ambeed | (4-Methoxy-35-dimethylpyridin-2-yl)methanamine dihydrochloride | 100mg | 624121460 | A589550 | MFCD12026975 | 239.14 | C9H16Cl2N2O
Ambeed | (R)-2-(((2S3S)-4-((E)-3-((R)-1-Carboxy-2-(34-dihydroxyphenyl)ethoxy)-3-oxoprop-1-en-1-yl)-2-(34-dihydroxyphenyl)-7-hydroxy-23-dihydrobenzofuran-3-carbonyl)oxy)-3-(34-dihydroxyphenyl)propanoic acid | 5mg | 491169047 | A179169 | 121521-90-2 | 718.620 | C36H30O16
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Apexbio Technology LLC Rofecoxib 162011-90-7 250mg
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Rofecoxib (CAS 162011-90-7) is a selective inhibitor of cyclooxygenase-2 (COX-2) designed to provide anti-inflammatory effects with improved gastrointestinal tolerance compared to non-selective NSAIDs It demonstrates potent inhibition of COX-2 in cell-based assays with IC50 values ranging from 18 to 46 nM In osteosarcoma cells Rofecoxib suppresses prostaglandin E2 (PGE2) synthesis (IC50 26 nM) and inhibits recombinant human COX-2 in stably transfected CHO cells (IC50 18 nM) In biochemical assays using purified human COX-2 the IC50 is 0 34 M In vivo Rofecoxib reduces carrageenan-induced edema and hyperalgesia in rats (ID50 1 1 5 mg/kg) It is widely used in studies investigating COX-2-mediated inflammatory pathways and analgesia
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Enzo Life Sciences PI-103 (1mg). CAS: 371935-74-9
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Potent, cell permeable and ATP-competitive inhibitor of DNA-PK, phosphoinositide 3-kinase (PI(3)K), the rapamycin-sensitive (mTORC1) and rapamycin-insensitive (mTORC2) complexes of the protein kinase mTOR. Exhibits little activity towards a panel of more than 40 other kinases even at concentrations as high as 10µM. Effectively blocks cell proliferation in glioma cell lines both in vitro and in vivo. Alternative name: 3-(4-(4-Morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl)phenol. Purity: ≥97% (HPLC). Solubility: Soluble in DMSO (5mg/ml; warm). Long Term Storage: -20°C.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC MEDCHEMEXPRESS LLC
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
5000701440 LEUCROSE 250MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC MEDCHEMEXPRESS LLC
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
5000703845 CRAC INTERMEDIATE 2 250MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC MEDCHEMEXPRESS LLC
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
5000703844 5 -4 -CARBOXY1 1 250MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC MEDCHEMEXPRESS LLC
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
5000586413 BUTYLHYDROXYANISOLE 250MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Ambeed AMBEED
5000866644 ETHYL 2-4-METHYLPHENYLSULF 5GR
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Apexbio Technology LLC SB590885 405554-55-4 250mg
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
SB590885 is a small-molecule inhibitor targeting B-Raf kinase It is designed to inhibit B-Raf activity thereby regulating the MAPK signaling pathway SB590885 exerts its biological activity primarily through direct binding to the ATP-binding pocket of B-Raf stabilizing its active conformation In cellular models harboring the B-Raf V600E mutation SB590885 demonstrates preferential inhibition with a Ki value of 0 16 nM for oncogenic B-Raf and shows significantly lower affinity for C-Raf Based on these pharmacological properties SB590885 holds research potential in studying B-Raf-driven tumorigenesis and evaluating therapeutic strategies targeting aberrant MAPK signaling pathways
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Histone H4 Human/Xe 5ug
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Histone H4 proteins are core components of nucleosomes which compact DNA into chromatin and regulate DNA accessibility during cellular processes Histones including H4 play critical roles in transcriptional regulation DNA repair replication and chromosome stability Histone H4 Protein Human/Xenopus laevis is the recombinant Xenopus laevis-derived Histone H4 protein expressed by E coli with tag free
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Ambeed AMBEED
5000868595 ETHYL 4-NITROPHENYLCARBAMA 1GR
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More